5 research outputs found
Black-Skin project of the Multiannual information society support programme 2001-2008 :Black-Skin Dermatology Online - Contribution to teledermatology: Half-yearly activity
I2/2F/206info:eu-repo/semantics/nonPublishe
Medical and surgical management of paraneoplastic pyoderma gangrenosum: a case report and review of the literature
We present a case of a 44-year-old male with pyoderma gangrenosum (PG) presenting simultaneously with diagnosis of acute leukemia. His skin disease was stabilized with corticosteroids and most lesions cleared after chemotherapy-induced remission of the malignancy, but the largest lesion remained necrotic. Surgical treatment of the large necrotic ulcer included debridement followed by split-thickness skin graft while maintaining corticoid therapy. Unfortunately, relapse of the pyoderma gangrenosum with bullous lesions heralded relapse of the ultimately fatal malignancy. This case illustrates: (1) PG presenting simultaneously with a haematologic malignancy (2) Relapse with atypical bullous lesions with return of the malignancy and (3) The use of surgical modalities in managing patients with PG, a disease notorious for surgical complications