A spectral and spatial analysis of eta Carinae's diffuse X-ray emission using CHANDRA

The luminous unstable star (star system) eta Carinae is surrounded by an optically bright bipolar nebula, the Homunculus and a fainter but much larger nebula, the so-called outer ejecta. As images from the EINSTEIN and ROSAT satellites have shown, the outer ejecta is also visible in soft X-rays, while the central source is present in the harder X-ray bands. With our CHANDRA observations we show that the morphology and properties of the X-ray nebula are the result of shocks from fast clumps in the outer ejecta moving into a pre-existing denser circumstellar medium. An additional contribution to the soft X-ray flux results from mutual interactions of clumps within the ejecta. Spectra extracted from the CHANDRA data yield gas temperatures kT of 0.6-0.76 keV. The implied pre-shock velocities of 670-760 km/s are within the scatter of the velocities we measure for the majority of the clumps in the corresponding regions. Significant nitrogen enhancements over solar abundances are needed for acceptable fits in all parts of the outer ejecta, consistent with CNO processed material and non-uniform enhancement. The presence of a diffuse spot of hard X-ray emission at the S condensation shows some contribution of the highest velocity clumps and further underlines the multicomponent, non-equilibrium nature of the X-ray nebula. The detection of an X-ray ``bridge'' between the northern and southern part of the X-ray nebula and an X-ray shadow at the position of the NN bow can be attributed to a large expanding disk, which would appear as an extension of the equatorial disk. No soft emission is seen from the Homunculus, or from the NN bow or the ``strings''.Comment: 15 pages, 10 figures, accepted by A&A; paper including images with full resolution available at http://www.astro.ruhr-uni-bochum.de/kweis/publications.htm

Supernova Remnants in the Magellanic Clouds. V. The Complex Interior Structure of the N206 SNR

The N206 supernova remnant (SNR) in the Large Magellanic Cloud (LMC) has long been considered a prototypical "mixed morphology" SNR. Recent observations, however, have added a new twist to this familiar plot: an elongated, radially-oriented radio feature seen in projection against the SNR face. Utilizing the high resolution and sensitivity available with the Hubble Space Telescope, Chandra, and XMM-Newton, we have obtained optical emission-line images and spatially resolved X-ray spectral maps for this intriguing SNR. Our findings present the SNR itself as a remnant in the mid to late stages of its evolution. X-ray emission associated with the radio "linear feature" strongly suggests it to be a pulsar-wind nebula (PWN). A small X-ray knot is discovered at the outer tip of this feature. The feature's elongated morphology and the surrounding wedge-shaped X-ray enhancement strongly suggest a bow-shock PWN structure.Comment: 41 pages including 7 figures, accepted for publication by the Astrophysical Journa

Chandra Observations of the Crab-like Supernova Remnant G21.5-0.9

Chandra observations of the Crab-like supernova remnant G21.5-0.9 reveal a compact central core and spectral variations indicative of synchrotron burn-off of higher energy electrons in the inner nebula. The central core is slightly extended, perhaps indicating the presence of an inner wind-shock nebula surrounding the pulsar. No pulsations are observed from the central region, yielding an upper limit of ~40% for the pulsed fraction. A faint outer shell may be the first evidence of the expanding ejecta and blast wave formed in the initial explosion, indicating a composite nature for G21.5-0.9.Comment: 4 pages, 2 figures, formatted with emulateapj, submitted to ApJ

Verification of the PROS timing analysis package

ROSAT observations of known pulsars are used to verify the functions of timing programs. The Crab Pulsar and PSR 0540-69, with 33 and 50 millisecond periods, are used to examine the fast Fourier transform and the epoch-folding task used to search for periodic signals. These fast pulsars provide a more vigorous test of the system than those with periods of a few seconds

Guiding the Way to Gamma-Ray Sources: X-ray Studies of Supernova Remnants

Supernova remnants have long been suggested as a class of potential counterparts to unidentified gamma-ray sources. The mechanisms by which such gamma-rays can arise may include emission from a pulsar associated with a remnant, or a variety of processes associated with energetic particles accelerated by the SNR shock. Imaging and spectral observations in the X-ray band can be used to identify properties of the remnants that lead to gamma-ray emission, including the presence of pulsar-driven nebulae, nonthermal X-ray emission from the SNR shells, and the interaction of SNRs with dense surrounding material.Comment: 16 pages, 11 figures, To appear in the proceedings of the workshop: "The Nature of the Unidentified Galactic Gamma-Ray Sources" held at INAOE, Mexico, October 2000, (A.Carraminana, O. Reiner and D. Thompson, eds.

Faecal immunochemical test for patients with 'high-risk' bowel symptoms: a large prospective cohort study and updated literature review

Background: We evaluated whether faecal immunochemical testing (FIT) can rule out colorectal cancer (CRC) among patients presenting with ‘high-risk’ symptoms requiring definitive investigation. Methods: Three thousand five hundred and ninety-six symptomatic patients referred to the standard urgent CRC pathway were recruited in a multi-centre observational study. They completed FIT in addition to standard investigations. CRC miss rate (percentage of CRC cases with low quantitative faecal haemoglobin [f-Hb] measurement) and specificity (percentage of patients without cancer with low f-Hb) were calculated. We also provided an updated literature review. Results: Ninety patients had CRC. At f-Hb < 10 µg/g, the miss rate was 16.7% (specificity 80.1%). At f-Hb < 4 µg/g, the miss rate was 12.2% (specificity 73%), which became 3.3% if low FIT plus the absence of anaemia and abdominal pain were considered (specificity 51%). Within meta-analyses of 9 UK studies, the pooled miss rate was 7.2% (specificity 74%) for f-Hb < 4 µg/g. Discussion: FIT alone as a triage tool would miss an estimated 1 in 8 cases in our study (1 in 14 from meta-analysis), while many people without CRC could avoid investigations. FIT can focus secondary care diagnostic capacity on patients most at risk of CRC, but more work on safety netting is required before incorporating FIT triage into the urgent diagnostic pathway

RXTE Observations of an Outburst of Recurrent X-ray Nova GS 1354-644

We present the results of Rossi X-ray Timing Explorer observations of GS 1354-644 during a modest outburst in 1997-1998. The source is one of a handful of black hole X-ray transients that are confirmed to be recurrent in X-rays. A 1987 outburst of the same source observed by Ginga was much brighter, and showed a high/soft spectral state. In contrast the 1997-1998 outburst showed a low/hard spectral state. Both states are typical for black hole binaries. The RXTE All Sky Monitor observed an outburst duration of 150 to 200 days. PCA and HEXTE observations covered ~70 days near the maximum of the light curve and during the flux decline. Throughout the observations, the spectrum can be approximated by Compton upscattering of soft photons by energetic electrons. The hot electron cloud has a temperature kT ~30 keV and optical depth tau~4--5. To fit the data well an additional iron fluorescent line and reflection component are required, which indicates the presence of optically thick cool material, most probably in the outer part of the accretion disk. Dramatic fast variability was observed, and has been analyzed in the context of a shot noise model. The spectrum appeared to be softest at the peaks of the shot-noise variability. The shape of the power spectrum was typical for black hole systems in a low/hard state. We note a qualitative difference in the shape of the dependence of fractional variability on energy, when we compare systems with black holes and with neutron stars. Since it is difficult to discriminate these systems on spectral grounds, at least in their low/hard states, this new difference might be important.Comment: 12 pages, 9 figures, accepted for publication in ApJ (Feb. 2000, v.530), uses emulateapj.st

Quantitative faecal immunochemical test for patients with 'high risk' bowel symptoms: a prospective cohort study

Objectives: To evaluate whether quantitative measurement of faecal haemoglobin (f-Hb) using faecal immunochemical testing (FIT) can be used to rule out colorectal cancer (CRC) for patients who present to primary care with ‘high risk’ symptoms defined by national guidelines for urgent referral for suspected cancer (NICE NG12). / Design: Prospective cohort study carried out between April 2017 and March 2019. / Setting: 59 GP practices in London and 24 hospitals in England. / Participants: Symptomatic patients in England referred to the urgent CRC pathway who provided a faecal sample for FIT in addition to standard investigations for cancer. / Main outcome measures: CRC was confirmed by established clinical and histopathology procedures. f-Hb (μg per gram of stool) was measured in a central laboratory blinded to cancer outcome. We calculated sensitivity (percentage of patients with CRC who have f-Hb exceeding specified cut-offs); false-positive rate [FPR] (percentage of patients without CRC whose f-Hb exceeds the same cut-offs); and positive predictive value [PPV] (percentage of all patients with f-Hb above the cut-offs who have CRC). / Results: 4676 patients were recruited of whom 3596 patients were included (had a valid FIT test and a known definitive diagnosis). Among the 3596, median age was 67 years, 53% were female and 78% had colonoscopy. 90 patients were diagnosed with CRC, 7 with other cancers, and 3499 with no cancer found. f-Hb did not correlate with age, sex or ethnicity. Using f-Hb ≥4μg/g (lowest limit of detection), sensitivity, FPR and PPV were 87.8%, 27.0% and 7.7% respectively. Using f-Hb ≥10μg/g, the corresponding measures were 83.3%, 19.9% and 9.7%. 15 patients with CRC had f-Hb below 10μg/g. If FIT had been used at thresholds of 10μg/g or 4μg/g, 1 in 6 or 1 in 8 patients with cancer respectively would have been missed. If the absence of anaemia or abdominal pain is used alongside f-Hb 10 μg/g, only 1 in 18 cancers would be missed but 56% of people without CRC could potentially avoid further investigations including colonoscopies. / Conclusions: In our study, if FIT alone had been used to determine urgent referral for patients with ‘high risk’ symptoms for definitive cancer investigation, some patients with bowel cancer would not have been diagnosed. If used in conjunction with clinical features, particularly in the absence of anaemia, the efficacy of FIT is significantly improved. With appropriate safety netting, FIT could be used to focus secondary care diagnostic capacity on patients most at risk of CRC

Practical free-space quantum key distribution over 1 km

A working free-space quantum key distribution (QKD) system has been developed and tested over an outdoor optical path of ~1 km at Los Alamos National Laboratory under nighttime conditions. Results show that QKD can provide secure real-time key distribution between parties who have a need to communicate secretly. Finally, we examine the feasibility of surface to satellite QKD.Comment: 5 pages, 2 figures, 2 tables. Submitted to Physics Review Letters, May 199

Daylight quantum key distribution over 1.6 km

Quantum key distribution (QKD) has been demonstrated over a point-to-point $\sim1.6$-km atmospheric optical path in full daylight. This record transmission distance brings QKD a step closer to surface-to-satellite and other long-distance applications.Comment: 4 pages, 2 figures, 1 table. Submitted to PRL on 14 January 2000 for publication consideratio