34 research outputs found
Immunosuppression minimization in kidney transplant recipients hospitalized for COVID-19
Get PDFBackground. Immunosuppressed patients such as kidney transplant recipients (KTs) have increased mortality risk in the setting of coronavirus disease 2019 (COVID-19). The role and management of chronic immunosuppressive therapies during COVID-19 must be characterized. Methods. Herein, we report the follow-up of a cohort of 47 KTs admitted at two Spanish Kidney Transplant Units, who survived COVID-19. The impact of the management of immunosuppression during COVID-19 on graft function and immunologic events was evaluated. Results. At least one immunosuppressive agent was withdrawn in 83% of patients, with antimetabolites being the most frequent. Steroids were generally not stopped and the dose was even increased in 15% of patients as part of the treatment of COVID-19. Although immunosuppressive drugs were suspended during a median time of 17 days, no rejection episodes or de novo donorspecific antibodies were observed up to 3 months after discharge, and no significant changes occurred in calculated panel reactive antibodies. Acute graft dysfunction was common (55%) and the severity was related to tacrolimus trough levels, which were higher in patients receiving antivirals. At the end of follow-up, all patients recovered baseline kidney function. Conclusions. Our observational study suggests that immunosuppression in KTs hospitalized due to COVID-19 could be safely minimized
Detailed shelter response profile Somalia: local building cultures for sustainable and resilient habitats
No full textInternational audienceThis publication is part of the series of documents “Local Building Cultures for sustainable and resilient habitats” that was launched in 2016. Several documents have been produced after a disaster (Fiji, Ecuador, Haiti) or before a disaster strikes as a preparedness tool (Bangladesh, Tonga, Malawi, Nepal). Most profiles have been elaborated for situations of both protracted crises and disaster contexts (Ethiopia, Democratic Republic of Congo, Burkina Faso, Yemen, Venezuela, Somalia, North-West Syria…). This Profile was produced from September 2022 to January 2023. The process was codirected by CRAterre and Somalia Shelter Cluster and more than 20 people representing almost 20 Somali-based organizations have contributed to the process. Apart from local contributions, a dedicated literature review of more than 40 documents (see Sources consulted to produce this document) was achieved. The profile has been revised by several international and Somali experts and shelter and housing actors in Somalia. This document summarizes and disseminates strengths of local building cultures, including a variety of hazard-resistant practices; considerations about disaster prevention, risk reduction and mitigation measures; environmental impacts; knowledge and experience developed by local communities; etc. These aspects have been identified, analyzed and many of them validated over the years
Malawi, detail shelter response profile: local building cultures for sustainable and resilient habitats
No full textInternational audienceThis document introduces reference data on local building cultures and local sociocultural resilient strategies. These references are to be considered as a basis for the elaboration of project-specific strategies and also as a grid of analysis with a first set of conclusions. Context and details will differ from one place to another and stakeholders will benefit from the collected data in order to make comprehensive and accurate decisions.SRPs have several complementary objectives:-To help recognise the importance of understanding a context before proposing any action or project.- To favour the development of shelter and human settlements responses (preparedness, early-recovery or later phases linking with development stages) more focused on localization, reduction of climate change impact, and promotion of self-recovery strategies.- To help better take into account the existing construction sector, natural and human resources, local knowledge, solutions and good practices, and local cultural and social practices such as existing DRR knowledge, know-how and techniques at various scales (materials, building systems, house, compound, settlement organisation).- To give a non exhaustive overview of a country or territory: demographic, cultural, social and economic data; hazards, environment and climate change impacts; impact of crises in the population; HLP issues; legal and institutional framework; construction sector, etc., and so to help orient practitioners in new contexts.- To eventually become an advocacy tool for the shelter sector/cluster members, agencies, donors, or local authorities for more localized actions, more focused on promoting self-recovery and communities’ resilience
Manuel de Diagnostic de la Construction Locale GTA DRC_201907 CONSTRUCTION LOCALE
No full textLe présent document a pour but d’expliquer le déroulement et les objectifs de l’étude diagnostic sur la construction locale(abri/logement et habitat) de manière compréhensive afin de pouvoir formuler des projets humanitaires dans le secteur Abris / Logement en RDC. Il reprend l’ensemble des étapes du diagnostic et est destiné aux techniciens et techniciennes du secteur Abris / Logement en RDC
Manuel de diagnostic de la construction locale
No full textLe présent document a pour but d’expliquer le déroulement et les objectifs de l’étude diagnostic sur la construction locale(abri/logement et habitat) de manière compréhensive afin de pouvoir formuler des projets humanitaires dans le secteur Abris / Logement en RDC. Il reprend l’ensemble des étapes du diagnostic et est destiné aux techniciens et techniciennes du secteur Abris / Logement en RDC
