Malva neglecta Wallr. (Ebegümeci)’nın In vitro Biyoaktif ve Fitokimyasal Özellikleri

M. neglecta çok yıllık otsu bir bitkidir ve Malvaceae familyasında yer almaktadır. Bu bitki ülkemizde her türlü toprakta kendiliğinden yetişir ve taze sürgünleri ile yaprakları sebze olarak tüketilir. Bu çalışmada M. neglecta toprak üstü kısımlarının su, etanol ve metanol ekstraktlarının antiradikal, antimikrobiyal, antikanser ve fitokimyasal içerikleri incelenmiştir. Elde edilen sonuçlara göre, M. neglecta toprak üstü kısımlarının yüksek antiradikal, antimikrobiyal, antikanser aktiviteye ve fitokimyasal içeriğe sahip olduğu anlaşılmıştır

In vitro Antiradical, Antimicrobial and Antiproliferative Activities and Phytochemical Compositions of Endemic Alcea calvertii (Boiss) Boiss. Flowers

Alcea calvertii (Boiss) Boiss. is belonged to Malvaceae family, and it is a perennial herbaceous endemic plant. Alcea genus plants are grown as ornamental plants in the gardens. In the present study, the antiproliferative, antimicrobial, antiradical activities and phytochemical compositions of ethanol, water, methanol and acetone extracts of A. calvertii flowers were examined. A. calvertii flowers water, ethanol, methanol and acetone extracts are lower scavenged DPPH, ABTS and OH radicals than standard antioxidant trolox. A. calvertii flowers contain vitamins, sterols, flavonoids and phenolic acids, dominated by vanillic acid, gallic acid, catechin, δ-tocopherol, ergosterol and vitamin D. A. calvertii flowers water extract showed better antiproliferative activities than other extracts against to MCF-7 and HCT-116 cell lines. A. calvertii flowers methanol extract showed higher antiproliferative effect against to LNCaP cell lines

Endemik Alcea calvertii (Boiss) Boiss. Çiçeklerinin In vitro Antiradikal, Antimikrobiyal ve Antiproliferatif Aktiviteleri ve Fitokimyasal Kompozisyonu

Alcea calvertii (Boiss) Boiss. is belonged to Malvaceae family, and it is a perennial herbaceous endemic plant. Alcea genus plants are grown as ornamental plants in the gardens. In the present study, the antiproliferative, antimicrobial, antiradical activities and phytochemical compositions of ethanol, water, methanol and acetone extracts of A. calvertii flowers were examined. A. calvertii flowers water, ethanol, methanol and acetone extracts are lower scavenged DPPH, ABTS and OH radicals than standard antioxidant trolox. A. calvertii flowers contain vitamins, sterols, flavonoids and phenolic acids, dominated by vanillic acid, gallic acid, catechin, δ-tocopherol, ergosterol and vitamin D. A. calvertii flowers water extract showed better antiproliferative activities than other extracts against to MCF-7 and HCT-116 cell lines. A. calvertii flowers methanol extract showed higher antiproliferative effect against to LNCaP cell lines