737 research outputs found

    Top Notch Support for eBooks

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    Come learn tips and tricks for delivering top notch technical support for eBooks. Library staff are the front line technical support for a growing number of patrons with diverse technical abilities wanting to access eBooks. We’ll share VPL’s unique team approach and innovative techniques for delivering technical support for your eBook collection. In this session, participants will learn: How to apply reference interview skills to technical support. How to create effective tools to use with patrons, including templates and on-the-spot screencasts. How to build an effective ebook-support team in your reference departmen

    Market Integration of Farmed Trout in Germany

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    Price formation and integration of markets supplied by both farmed and captured fish is studied. Markets for trout and potential substitutes imported to Germany are analysed, and market delineation and market leaders identified. It is found that markets for small portion-sized farmed trout with white meat are related to, rather than completely separate from, other fish markets, and that markets for these trout are more closely linked to markets for captured fish than to farmed salmon. The implications are that although the part of the trout business operating with small freshwater ponds remains relatively unaffected by developments in other fish markets, careful attention should be paid to markets for and management of capture fisheries like cod, halibut, redfish, and mackerel, than to markets for farmed salmon.Price formation, market integration, captured-farmed fish, Production Economics, F15, Q21, Q22,

    Ectomycorrhizal Fungal Communities in Urban Parks Are Similar to Those in Natural Forests but Shaped by Vegetation and Park Age

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    Ectomycorrhizal (ECM) fungi are important mutualists for the growth and health of most boreal trees. Forest age and its host species composition can impact the composition of ECM fungal communities. Although plentiful empirical data exist for forested environments, the effects of established vegetation and its successional trajectories on ECM fungi in urban greenspaces remain poorly understood. We analyzed ECM fungi in 5 control forests and 41 urban parks of two plant functional groups (conifer and broadleaf trees) and in three age categories (10, similar to 50, and > 100 years old) in southern Finland. Our results show that although ECM fungal richness was marginally greater in forests than in urban parks, urban parks still hosted rich and diverse ECM fungal communities. ECM fungal community composition differed between the two habitats but was driven by taxon rank order reordering, as key ECM fungal taxa remained largely the same. In parks, the ECM communities differed between conifer and broadleaf trees. The successional trajectories of ECM fungi, as inferred in relation to the time since park construction, differed among the conifers and broadleaf trees: the ECM fungal communities changed over time under the conifers, whereas communities under broadleaf trees provided no evidence for such age-related effects. Our data show that plant-ECM fungus interactions in urban parks, in spite of being constructed environments, are surprisingly similar in richness to those in natural forests. This suggests that the presence of host trees, rather than soil characteristics or even disturbance regime of the system, determine ECM fungal community structure and diversity. IMPORTANCE In urban environments, soil and trees improve environmental quality and provide essential ecosystem services. ECM fungi enhance plant growth and performance, increasing plant nutrient acquisition and protecting plants against toxic compounds. Recent evidence indicates that soil-inhabiting fungal communities, including ECM and saprotrophic fungi, in urban parks are affected by plant functional type and park age. However, ECM fungal diversity and its responses to urban stress, plant functional type, or park age remain unknown. The significance of our study is in identifying, in greater detail, the responses of ECM fungi in the rhizospheres of conifer and broadleaf trees in urban parks. This will greatly enhance our knowledge of ECM fungal communities under urban stresses, and the findings can be utilized by urban planners to improve urban ecosystem services.Peer reviewe

    Investigating Embryonic Expression Patterns and Evolution of AHI1 and CEP290 Genes, Implicated in Joubert Syndrome

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    Joubert syndrome and related diseases (JSRD) are developmental cerebello-oculo-renal syndromes with phenotypes including cerebellar hypoplasia, retinal dystrophy and nephronophthisis (a cystic kidney disease). We have utilised the MRCWellcome Trust Human Developmental Biology Resource (HDBR), to perform in-situ hybridisation studies on embryonic tissues, revealing an early onset neuronal, retinal and renal expression pattern for AHI1. An almost identical pattern of expression is seen with CEP290 in human embryonic and fetal tissue. A novel finding is that both AHI1 and CEP290 demonstrate strong expression within the developing choroid plexus, a ciliated structure important for central nervous system development. To test if AHI1 and CEP290 may have co-evolved, we carried out a genomic survey of a large group of organisms across eukaryotic evolution. We found that, in animals, ahi1 and cep290 are almost always found together; however in other organisms either one may be found independent of the other. Finally, we tested in murine epithelial cells if Ahi1 was required for recruitment of Cep290 to the centrosome. We found no obvious differences in Cep290 localisation in the presence or absence of Ahi1, suggesting that, while Ahi1 and Cep290 may function together in the whole organism, they are not interdependent for localisation within a single cell. Taken together these data support a role for AHI1 and CEP290 in multiple organs throughout development and we suggest that this accounts for the wide phenotypic spectrum of AHI1 and CEP290 mutations in man

    When who and how matter: explaining the success of referendums in Europe

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    This article aims to identify the institutional factors that make a referendum successful. This comparative analysis seeks to explain the success of top-down referendums organized in Europe between 2001 and 2013. It argues and tests for the main effect of three institutional factors (popularity of the initiator, size of parliamentary majority, and political cues during referendum campaigns) and controls for the type of referendum and voter turnout. The analysis uses data collected from referendums and electoral databases, public opinion surveys, and newspaper articles. Results show that referendums proposed by a large parliamentary majority or with clear messages from political parties during campaign are likely to be successful

    Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity

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    There are hints of an altered mitochondrial function in obesity. Nuclear-encoded genes are relevant for mitochondrial function (3 gene sets of known relevant pathways: (1) 16 nuclear regulators of mitochondrial genes, (2) 91 genes for oxidative phosphorylation and (3) 966 nuclear-encoded mitochondrial genes). Gene set enrichment analysis (GSEA) showed no association with type 2 diabetes mellitus in these gene sets. Here we performed a GSEA for the same gene sets for obesity. Genome wide association study (GWAS) data from a case-control approach on 453 extremely obese children and adolescents and 435 lean adult controls were used for GSEA. For independent confirmation, we analyzed 705 obesity GWAS trios (extremely obese child and both biological parents) and a population-based GWAS sample (KORA F4, n = 1,743). A meta-analysis was performed on all three samples. In each sample, the distribution of significance levels between the respective gene set and those of all genes was compared using the leading-edge-fraction-comparison test (cut-offs between the 50(th) and 95(th) percentile of the set of all gene-wise corrected p-values) as implemented in the MAGENTA software. In the case-control sample, significant enrichment of associations with obesity was observed above the 50(th) percentile for the set of the 16 nuclear regulators of mitochondrial genes (p(GSEA,50) = 0.0103). This finding was not confirmed in the trios (p(GSEA,50) = 0.5991), but in KORA (p(GSEA,50) = 0.0398). The meta-analysis again indicated a trend for enrichment (p(MAGENTA,50) = 0.1052, p(MAGENTA,75) = 0.0251). The GSEA revealed that weak association signals for obesity might be enriched in the gene set of 16 nuclear regulators of mitochondrial genes

    Effect of polarimetric nonregularity on the spin of three-dimensional polarization states

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    While the spin of two-dimensional polarization states admits a simple representation, its physical interpretation for three-dimensional (3D) mixed polarization states requires a more involved analysis. In this work, we address the spin structure of the electric field of a general 3D polarization state by taking advantage of the characteristic decomposition and the recently introduced notion of nonregularity associated with 3D states. We show that a nonregular polarization state necessarily has an additional spin component due to the state''s genuinely 3D nature, and both the orientation and magnitude of the spin are regulated by the degree of nonregularity. The results provide new physical insight into partially polarized evanescent and tightly focused light fields in which strong nonregular character has recently been demonstrated

    Intensity and spin anisotropy of three-dimensional polarization states

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    Anisotropy is a natural feature of polarization states, and only fully random three-dimensional (3D) states exhibit complete isotropy. In general, differences between the strengths of the electric field components along the three orthogonal directions give rise to intensity anisotropy. Moreover, polarization states involve an average spin whose inherent vectorial nature constitutes a source of spin anisotropy. In this work, appropriate descriptors are identified to characterize quantitatively the levels of intensity anisotropy and spin anisotropy of a general 3D polarization state, leading to a novel interpretation for the degree of polarimetric purity as a measure describing the overall polarimetric anisotropy of a 3D optical field. The mathematical representation, as well as the physical features of completely intensity-isotropic 3D polarization states with a maximum spin anisotropy, are also examined. The results provide new insights into the polarimetric field structure of random 3D electromagnetic light states. (C) 2019 Optical Society of Americ
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