586 research outputs found

    Financial Openness and Total Factor Productivity in Turkey

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    AbstractFinancial openness, which can be defined as integration into international financial markets, can cause significant changes in countries’ production structures and in the methods of doing business through the quantity and quality of international capital flows. The aim of this study is to analyze the effects of financial openness on TFP as a long-term structural indicator in Turkey. Empirical results reveal that the effect of financial openness on TFP is significant and positive together with the other determinants of TFP specified as human capital, innovation, foreign direct investment, financial development, macroeconomic stability and governance indicators in our sample period. However, the relationship between financial openness and TFP presents different pictures when sub periods are taken into consideration. The results of the analysis point out that structural policies addressing to TFP determinants are likely to increase the long term potential growth rate, the development level and the welfare of Turkey. Therefore, efforts should be made to enhance the capability and extent of exploiting the advantages of financial openness by means of comprehensive and complementary policies at macro level

    Romatoid artritli hastalarda sosyal rol katılımının yaşam kalitesine etkisi

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    Objective: The aim of this study was to explore the impact of social role participation on quality of life in rheumatoid arthritis (RA) patients. Material and Methods: This study was conducted on 100 RA patients who applied to our outpatient clinic and 95 healthy controls. The outcome measures included Visual Analogue Scale (VAS) (rest and activity pain), Disease Activity Score (DAS-28) Scale, Rheumatoid Arthritis Quality of Life Questionnaire (RAQoL), and Social Role Participation Questionnaire (SRPQ) (role limitations, salience, satisfaction). Results: There were statistically significant differences in SRPQ role salience, SRPQ role limitation, and SRPQ role satisfaction scores between the RA patients and the healthy individuals (p<0.001). The RAQoL scores were positively correlated with SRPQ limitation scores and negatively correlated with SRPQ role satisfaction and SRPQ role salience scores (all, p<0.001). Negative correlations were found between SRPQ scores (salience, satisfaction) and DAS-28 and VAS (rest and activity pain) scores (all, p<0.05). Positive correlations were found between SRPQ role limitations scores and DAS-28 and VAS (rest and activity pain) scores (all, p<0.05). There was no correlation between SRPQ domains scores and age or disease duration in RA patients (all, p>0.05). RAQoL was positively correlated with VAS (rest and activity pain) and DAS-28 scores (all, p<0.001). Conclusion: This study showed that there is an association between social role participation and quality of life in RA patients. So, it may be useful to take into account the evaluation of social role participation in the management of RA patients.Amaç: Çalışmamızda, romatoid artrit (RA) hastalarında sosyal rol katılımının yaşam kalitesi üzerindeki etkisini araştırmayı amaçladık. Gereç ve Yöntemler: Bu çalışma polikliniğimize başvuran 100 RA hastası ve 95 sağlıklı kontrol üzerinde gerçekleştirildi. Sonuç ölçütlerinde Vizüel Analog Skalası (VAS) (istirahat ve aktivite ağrısı), Hastalık Aktivite Skoru [Disease Activity Score-28 (DAS-28)] Ölçeği, Romatoid Artrit Yaşam Kalitesi Ölçeği [Rheumatoid Arthritis Quality of Life Questionnaire (RAQoL)] ve Sosyal Rol Katılım Anketi [Social Role Participation Questionnaire (SRPQ)] (rol sınırlamaları, belirginlik, memnuniyet) kullanıldı. Bulgular: RA hastaları ve sağlıklı bireyler arasında SRPQ rol belirginliği, SRPQ rol sınırlaması ve SRPQ rol memnuniyetinde istatistiksel olarak anlamlı farklılıklar vardı (p<0,001). RAQoL ile SRPQ rol sınırlama arasında pozitif korelasyon ve RAQoL ile SRPQ rol memnuniyeti ve SRPQ rol belirginliği arasında ise negatif korelasyon bulundu (hepsi, p<0,001). SRPQ (belirginlik, memnuniyet) ile DAS-28 ve VAS (istirahat ve aktivite ağrısı) arasında negatif korelasyon tespit edildi (hepsi, p<0,05). SRPQ rol sınırlılıkları ile DAS28 ve VAS (istirahat ve aktivite ağrısı) arasında pozitif korelasyon tespit edildi (hepsi, p<0,05). RAQoL ile VAS (istirahat ve aktivite ağrısı) ve DAS-28 arasında pozitif korelasyon bulundu (hepsi, p<0,001). Sonuç: Bu çalışma, RA hastalarında sosyal rol katılımı ile yaşam kalitesi arasında bir ilişki olduğunu göstermiştir. Bu nedenle RA hastalarının tedavi yönetiminde, sosyal rol katılımının değerlendirilmesini dikkate almak faydalı olabilir

    Comparison of the effectiveness of local corticosteroid injection and extracorporeal shock wave therapy in patients with lateral epicondylitis

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    Serdaroglu Beyazal, Munevver/0000-0001-5903-5708WOS: 000368605500030PubMed: 26834345[Purpose] This study aimed to determine and compare the effectiveness of extracorporeal shock wave therapy and local corticosteroid injection in patients with lateral epicondylitis. [Subjects and Methods] Sixty-four patients with lateral epicondylitis were randomly divided into extracorporeal shock wave therapy and steroid injection groups. Patients were evaluated using hand grip strength, visual analog scale, and short-form McGill pain questionnaire at baseline and at 4 and 12 weeks post-treatment. [Results] Both groups showed statistically significant increase in hand grip strength and decreases on the visual analog scale and short form McGill pain questionnaire overtime. There was no statistically significant difference in the percentage of improvement in hand grip strength and on the short-form McGill pain questionnaire between groups at 4 weeks post-treatment, whereas the extracorporeal shock wave therapy group showed better results on the visual analog scale. the percentages of improvements in all 3 parameters were higher in the extracorporeal shock wave therapy group than in the injection group at 12 weeks post-treatment. [Conclusion] Both the extracorporeal shock wave therapy and steroid injection were safe and effective in the treatment of lateral epicondylitis. However, extracorporeal shock wave therapy demonstrated better outcomes than steroid injection at the long-term follow-up

    Introductory Chapter: The Latest Knowledge

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    Urticaria and Angioedema

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    Urticaria is a common mast cell–mediated dermatosis presenting with pruritic erythematous superficial plaques also known as hives or wheals. Angioedema is an acute condition manifesting as localized edema affecting the skin and mucous membranes. In contrast with urticaria, itching is often absent, the skin appears normal and the edema occurs in deeper dermal and subcutaneous tissues in angioedema. Spontaneous urticaria can either be acute lasting less than 6 weeks or chronic with a duration of more than 6 weeks. In acute urticaria cases, an underlying cause, mostly medications, foods and infections, may be found in approximately 50% of patients. However, spontaneous urticaria is generally idiopathic. First-line treatment option for both acute and chronic urticaria is non-sedating H1 antihistamines. Patients with recalcitrant disease are candidates for therapy with corticosteroids, immunosuppressives or omalizumab treatment. There are two different mechanisms causing angioedema. The first is mast cell mediated and is considered to be part of the spectrum of spontaneous or inducible urticarias. Patients present with angioedema alone or angioedema combined with urticaria. The second is bradykinin-induced angioedema, as observed in the hereditary angioedema and angiotensin-converting enzyme (ACE) inhibitor–induced angioedema

    Strychnos alkaloids: total synthesis, characterization, DFT investigations, and molecular docking with AChE, BuChE, and HSA

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    An efficient five steps, the protection-deprotection synthetic a novel synthetic routes to(+/-) noruleine (f)-uleine, are reported starting from tetrahydrocarbazole fused monoalkyl nitrile at C-2 position that is prepared on mul-tigram scale from 2-(3-ethyl-1-oxo-2,3,4,9-tetrahydro-1H-carbazol-2-yl)acetonitrile (1) as well as the key azocino [4,3-b]indole skeleton is constructed via the tetrafluoro-1,4-benzoquinone (TFB)-mediated cyclization of a tet-rahydrocarbazole derivative possessing direct amide synthesis from nitrile. As a result, Total synthesis of nor-uleine and uleine has been developed, which is accomplished in 4 and 5-steps synthesis of the ABCD tetracyclic of the strychnos alkaloids with an overall yield of 44% and 39%, respectively. The DFT computations were per-formed with B3LYP/6-311g(d,p) level to determine inter and intramolecular interactions and reactivity features of the compound 3-6. Also, TD-DFT computations were performed to characterize the electronic absorption spectra of all compounds. Last, the interactions of compounds 3-6 with selected targets AChE, BuChE, and HSA were evaluated in light of the molecular dockings. The bioactivity and drug-likeness scores revealed that com-pound 6 3-6 can be proper candidate for future drug-design studies more than the other compounds.Scientific and Technological Research Council of Turkey [TUBITAK] [112T503]Nesimi Uludag was supported by Scientific and Technological Research Council of Turkey [TUBITAK Project No.112T503]

    Waterland: (Re)Textualizing Histories and Historicizing the Past

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    Graham Swift's novel Waterland (1983) is about Thomas Crick, a history teacher. In his history lessons, Thomas Crick merges public history with his private history as well as local history of Fenlands where he lives, to face and to solve the mysteries of his past. Thus, by intermingling public, private and local histories, he erases all the boundaries between them and hence gives a different understanding/representation of history and also his history lessons become a journey to his past/history within public and local histories although the only reason for him to do so is to give less boring history lessons. In that sense, the novel meets on the same ground with the New Historicism, ourished in the mid-1980s as a “new” approach which challenges the traditional understanding of history as a grand-narrative and which focuses on how history is represented rather than what it represents. This article aims to analyze the novel Waterland which deconstructs and reconstructs the notion of history by focusing on the concepts of memory and time, and thus to elucidate how the novel challenges the traditional appreciation of history as a grand narrative by merging public, local and private histories with multiple representations of history

    Les transformations des registres d’action de TÜSİAD dans les années 1990 : le rôle de l’enjeu européen

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    Since the second half of the 1990s, Turkish political life has been markedly influenced by the growing importance of TÜSİAD, an entrepreneurs’ association which calls for a transformation of the political regime/political system. The association advocates a new, more democratic political system, referring to the reforms expected by the European institutions in the course of / as part of the EU integration process of Turkey. This situation is at odds with the initial goals of the association. TÜSİAD was founded by leading entrepreneurs with the aim of promoting “free entrepreneurship” in Turkey, in a situation where the founding membres felt “threatened” by the risk of an anti-liberal economy and/or a social environnement within which their businesses were not respected. This article analyses how this association, which originally aimed at promoting free-entrepreneurship and market economy, ended up upholding political and legal reforms aiming at the europeanization of the Turkish political system – and consequently, of Turkey

    İstanbul’da Konak Hayatı ve Konak Mimarisi (Samiha Ayverdi’nin İbrahim Efendi Konağı Kitabı Üzerinden Mimari Okumalar)

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    Osmanlı İmparatorluğu’nun yaklaşık beş yüz yıllık süre zarfında; çeşitli mahallere yerleşmiş, yerleşirken doğayı tahrip etmemiş ve yüzyıllar boyunca Yahya Kemal’in düşüncesiyle büyük bir mahalle gibi bir arada yaşamış Türk evleri, içinde bir dönemi değil bir kültürü barındırmaktadır. Zamanla değişmiş ve farklılaşmış ancak son dönemine kadar geleneklerinden taviz vermemeye çalışmıştır. Bu kültürün bir parçası olan İstanbul konakları da zamanla kendi üslubunu oluşturmuş ve içinde yaşattığı prensipleriyle Osmanlı tarihinde önemli bir yere sahip olmuştur. Sâmiha Ayverdi bu İstanbul konaklarından birinde yaşamış ve imparatorluğun çöküşüyle beraber konakların yok oluşunu eserlerine aktarmıştır. Özellikle İbrahim Efendi Konağı adlı eseri hikâye değil, yazarın Osmanlı’nın son dönemlerindeki İstanbul hatıralarından oluşmaktadır. İbrahim Efendi yazarın annesinin amcasıdır. Bu sebeple mekânlar görülerek kitaba aktarılmış ve bize somut örnekler verilmiştir. Bu somut örnekler 19. yüzyıl dönemindeki konak hayatını ve konak mimarisini kavramak adına geçmişe ışık tutacaktır. Bu çalışmanın ilk bölümünde amaç, kapsam ve yöntem hakkında bilgiler verilmiştir. İkinci bölümde İstanbul konaklarının temeli olan Türk evi ele alınmıştır. Tarihsel süreci, geçirdiği değişimler, kazandığı ya da kaybettiği özellikler belirtilmiştir. Plan tipleri incelenmiş ve mekânsal özelliklerine yer verilmiştir. Üçüncü bölümde konaklar; genel özellikleri, mekânsal birimleri ve yaşantısıyla araştırılıp günümüze kadar ayakta kalabilmiş ya da çeşitli sebeplerle ortadan kaybolmuş yapılara yer verilmiştir. Üçüncü bölümde Sâmiha Ayverdi’nin İbrahim Efendi Konağı eseriyle beraber incelenen diğer eserlerinden mimari okumalar yapılıp konak, köşk ve yalıların mahalle içindeki konumu, mekânsal özellikleri, teşkilat ve teşrifatı ele alınmıştır. Son bölümde ise çalışmanın değerlendirmesi yapılıp bir sonuca varılmıştır.During the Ottoman Empire’s approximate five hundred year time period; various locations were settled without vandalizing the nature and with the thought of Yahya Kemal, the Turkish homes lived together as a big neighborhood for centuries, sheltering a culture and not a period. Though this has changed and differentiated over time, the culture wasn’t compromised until the last period. As a part of this culture, Istanbul’s mansions created their own manner and have been in an important part of the Ottoman history with keeping principles alive. Samiha Ayverdi has lived in one of these mansions in Istanbul and carried in her pieces the way mansions were destroyed with the collapse of the Empire. Especially the ‘Ibrahim Effendi Konak’ non-fiction piece, and is composed of the author’s memories during the last periods of the Ottoman. Ibrahim Effendi is the author’s mother’s uncle. Therefore, depiction was given by viewing the places and concrete examples are provided for us. These concrete examples will light the past in order for us to comprehend the mansion’s architecture and lives during the 19th century. The first section of this thesis gives information about scope and procedure. The second section takes the Turkish home, which is the essential of Istanbul mansion. Its historical period and changes and, lost features are indicated. The plan types have been studied and spatial units have been specified. In the third section, mansions; have been explored and analyzed by its general features, spatial units and residence. It also includes structures that have sustained or destroyed because of various reasons. The third section takes all kinds of mansions’ locations in their neighborhoods, spatial characteristics, and systems based on reading that have been made on ‘Ibrahim Efendi Konagi’ and other pieces of Samiha Ayverdi. In the final section the thesis has been evaluated and came to a conclusion

    Tıg kaynak yöntemiyle boru-flanş kaynağında açısal distorsiyona kaynak akımı etkisinin incelenmesi

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    06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması, Düzenlenmesi ve Erişime Açılmasına İlişkin Yönerge” gereğince tam metin erişime açılmıştır.Gıda, ilaç ve diğer endüstriyel uygulamalarda boru flanş ürünleri yaygın olarak kullanılmaktadır. Borular ile flanşların birleştirilmesi, kaynaklı imalat yöntemiyle gerçekleştirilmektedir. Özellikle paslanmaz çelik malzemelerden boru- flanş kaynağında TIG kaynak yöntemi tercih edilmekte ve açısal distorsiyonlar büyük problem olmaktadır.Bu çalışmada Ø 139,7 mm ve 2 mm kalınlıktaki AISI 304 östenitik paslanmaz çelik boruların, 2 mm kalınlıktaki ve iç çapı 141 mm, dış çapı 240 mm AISI 304 östenitik paslanmaz çelik flanşlara TIG metod kaynak yöntemi ile birleştirilmesi dolgu telli ve dolgu telsiz koşullar için incelenmiştir. İncelemeler kaynak akımının sabit nüfuziyet değerleri ile açısal distorsiyona etkisini ve kaynak hızına etkisini içermektedir. Kaynak akımı 70 A, 80 A, 90 A, 100 A, 110 A değerleri çalışılmıştır. En uygun koşullar, dolgu telsiz 70 A kaynak akım değerinde elde edilmiştir.Pipe-flange has commonly been used in food, medicine and industrial applications. Combination of pipes and flanges were made with welding manufacturing method. In particular pipe flange welding made of stainless steel, TIG welding method has been preferred and angular distortions have been a great problem.In this thesis study, combining the austenitic stainless pipes having 139,7 mm diameter and 2 mm thickness and AISI 304 and austenitic stainless steel flanges having 141 mm interior and 240 mm exterior diameter and 2 mm thickness, and AISI 304 steel with TIG welding in two conditions with additional wire and without additional wire were investigated. The investigations contain the effect of welding current to angular distortion and the speed of welding with the values of welding current which was 70 A, 80 A, 90 A, 100 A, 110 A. It was concluded that the best conditions on the values of a welding current was 80 A without additional wire.In this research, combining the austenitic stainless pipes which are Ø 139,7 mm 2 mm and AISI 304 and austenitic stainless steel flanges which are 2 mm, 141 mm interior diameter, 240 mm exterior diameter and AISI 304 with the method of TIG welding for the conditions with additional wire and without additional wire were investigated. The investigations contain the effect of welding current to angular distortion and the speed of welding with the values of welding current which was 70 A, 80 A, 90 A, 100 A, 110 A. It was concluded that the best conditions on the values of a welding current was 70 A without additional wire
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