Arguments en faveur d'une modification du génome (introgression) du parasite humain Schistosoma haematobium par des gènes de S. bovis, au Niger

La caractérisation de schistosomes par la morphologie des oeufs intra-utérins des vers femelles et l'analyse des phénotypes des parasites observés pour la phosphatase acide après séparation électrophorétique suggère la présence de gènes de #S. bovis, parasite du bétail domestique, chez les schistosomoses issus de l'homme dans la région est du Niger et présumés appartenir à #S. haematobium. Cette introgression naturelle pourrait également implique #S. curassoni$, un autre schistosome du bétail sympatrique des 2 autres espèces dans cette région. (Résumé d'auteur

Gas migration in pre-compacted bentonite under elevated pore-water pressure conditions

Pre-compacted bentonite has long been proposed as a primary component of an engineered barrier system for the safe geological disposal of radioactive waste. Selection of properties such as the clay composition, compaction-state and clay-to-sand ratio varies in different disposal concepts. However, a sound understanding of the gas transport properties of the barrier material is often considered a necessary part of safety case development for a geological disposal facility. In this study, results are presented from two gas injection experiments conducted in Mx80 bentonite, under elevated pore-water pressure conditions. Test observations indicate that the conditions necessary for gas to enter this material are remarkably consistent, irrespective of the applied water pressure. As expected, an association is noted between the total stress experienced by the clay and the gas pressure at the moment of entry. Gas migration is interpreted as occurring by the formation and propagation of dilatant pathways within the bentonite. Local pore-pressure and stress measurements indicate that significant reworking of the clay can occur, resulting in meta-stable episodes of ‘pressure-cycling’, as gas seeks a stable escape pathway. These findings demonstrate the potential for ‘phases’ of pathway development and propagation within the buffer, resulting in successive migration episodes over the repository lifetime. Experiments also show the potential for gas entry into the buffer to occur as a result of declining pore-water pressure conditions. As such, the influence of significant deviations from hydrostatic conditions (for example, resulting from glacial loading) should not be neglected when considering gas interaction with the buffer over long timescales

Genetic variability in the compatibility between Schistosoma haematobium and its potential vectors in Niger : epidemiological implications

Une étude de la compatibilité de #Schistosoma haematobium envers ses vecteurs potentiels #Bulinus a été menée au Niger dans trois systèmes épidémiologiques : zones irriguées, mares temporaires, mares permanentes type guelta saharienne. Il a été montré que #Bulinus truncatus et #Bulinus senegalensis avec 71,5 % et 85,9 % de taux de réussite à l'infestation sont de bons hôtes intermédiaires alors que #Bulinus globosus et #Bulinus forskalii sont totalement incompatibles. Les combinaisons #S. haematobium - #B. truncatus sympatriques ou allopatriques donnent des résultats semblables. Ceci laisse supposer le manque d'isolement des populations de schistosomes et le grand brassage du génome du parasite par suite de la grande mobilité des populations humaines sahélienne

La schistosomose urinaire dans le massif saharien de l'Aïr (République du Niger)

Dans deux villages de l'Aïr (République du Niger), les auteurs ont trouvé une prévalence globale de #Schistosoma haematobium$de 24,1$ est l'hôte intermédiaire des schistosomes. Le rôle de ce mollusque dans la transmission de la schistosomose urinaire à Timia n'a pas été mis en évidence. Cemio de #Bulinus senegalensis$ présent dans les deux localités reste encore à préciser. (Résumé d'auteur

Neutron/gamma pulse shape discrimination in EJ-299-34 at high flux

The effect of scintillator geometry on the quality of neutron/γ pulse shape discrimination (PSD) in EJ-299 plastic scintillator, using a digital charge integration PSD algorithm has been studied. It is shown that the PSD Figure of Merit (FOM) reduces as the geometry of the scintillator moves from a cube-like shape towards a flat panel shape. The PSD performance in this material at high flux irradiation is investigated with performance deteriorating at rates of ∼107 photons/s. The use of EJ-299 for security applications, with a focus on active interrogation environments is explored in conjunction with a system capable of neutron/γ separation and localisation

Argon-photoion–Auger-electron Coincidence Measurements Following K-shell Excitation by Synchrotron Radiation

Argon photoion spectra have been obtained for the first time in coincidence with K-LL and K-LM Auger electrons, as a function of photon energy. The simplified charge distributions which result exhibit a much more pronounced photon-energy dependence than do the more complicated noncoincident spectra. In the near-K-threshold region, Rydberg shakeoff of np levels, populated by resonant excitation of K electrons, occurs with significant probability, as do double-Auger processes and recapture of the K photoelectron through postcollision interaction

RadICAL stack: A localisation method for dynamic gamma/neutron fields

A variation of the RadICAL (Radiation Imaging Cylinder Activity Locator) system capable of operating in a dynamic environment, such as that created by active interrogation techniques, has been developed. RadICAL is a novel method for locating a radiological source using a rotating detector element. The detector geometry is that of a thin sheet and is rotated to present a constantly changing surface area to the source; it therefore generates a characteristic temporal response which can be used to determine the source direction. The time required to determine the direction of a source make it unsuitable for dynamic environments and so an alternative method is presented that uses a stack of identical scintillator slabs positioned at fixed horizontal angles around a central axis. By comparing count rates from each slab to a standard response curve, using a specially developed algorithm, the direction of a source can be determined without the need to rotate the detector. EJ-299-33 plastic scintillator was used to allow detection of separate neutron and gamma events in a mixed field through pulse shape discrimination. A four element detector was built and shown to achieve a positional accuracy of approximately 4.4 degrees when exposed to a 1.44MBq 137 Cs source at distances of up to 2m. The same detector was used to discriminate separate neutron and gamma events in a mixed field, which allows for the possibility of locating a neutron source within a gamma rich environment