Typhoid Fever Complicated By Multiple Organ Involvement In A Child

A 12-year old girl was admitted to our clinic because of fever, headache, diarrhea and weakness for 10 days. Dyspne, tachycardia, hypotension, fever and letargy were determined in physical examination. The levels of urea, creatinine, aspartate aminotransferase, alanine aminotransferase were found to be increased. In echocardiography, myocardial dysfunction and low systolic functions were detected. Blood culture was positive for S.typhi. We report multiple organ involvement in a patient with typhoid fever and review the literature

Iatrogenic subclinic D hypervitaminosis: case report

Use of high dose vitamin D without evaluation physical examination and laboratory procedures may lead to important complications in childhood. In this case report the clinical and laboratory findings of 13 months old girl that given five D vitamin ampoule (300.000 U) in four months for growth failure were evaluated. The diagnosis of iatroghenic sub clinic D hypervitaminozis was determined with clinical history, laboratory and radiological findings. Hypercalcemia, low parathormon level, high 25(OH) D vitamin level, hypercalsiuria and meduller nephrocalsinosis were detected in results. The aim of this case report is evaluation of high dose vitamin D complications

Infantile iatrogenic cushing′s syndrome

High potency or/and extended use of topical corticosteroids, particularly in children, may cause suppression of the hypothalamopituitary-adrenal axis. However, iatrogenic Cushing′s syndrome in infantile age group is very rare and only a few patients have been reported to date in the literature. Here, we report a case of iatrogenic Cushing′s syndrome in a 6-month-old male child whose parents have admitted to the hospital for overweight and skin fragility

Sudden Infant Death Syndrome with Harlequin Fetus

The harlequin fetus, a severe variant of ichthyosis, occurs rarely, and these babies die within the first few days of life. Early retinoid therapy may improve the disorder and help increase survival rates. The exact cause of the sudden infant death syndrome of the suckling is not known and the incidence approximately is 0.1-0.3 %. In general, these babies looked well and healthy at the time of the sleeping but were found dead in their bed in the morning. We report a harlequin fetus with sudden infant death syndrome

Incidence and risk factors for retinopathy in premature infants with very low birth weight, in the South-East Region, Turkey

Giriş: Prematüre retinopatisi (PR) çocukluk döneminde görülen en önemli körlük nedenidir. İleri derecede düşük doğum ağırlıklı prematürelerin yaşam oranlarının artmasıyla PR sıklığında da artış görülmektedir. PR’nin en önemli risk faktörleri, düşük doğum ağırlığı ve erken gestasyonel dönemdir. Bu çalışmanın amacı, vücut ağırlığı 1500 gramın altında doğan prematüre bebeklerde, PR risk faktörlerini ve retinopati görülme oranlarını değerlendirmektir. Gereç ve Yöntem: Çalışmaya Ağustos 2010-Aralık 2102 tarihleri arasında yenidoğan yoğun bakım ünitemizde izlenen doğum haftası 32 haftanın ve doğum ağırlığı 1500 gramın altında olan 84 hasta alındı. Retinopati gelişen ve gelişmeyen iki grup arasında risk faktörleri açısından karşılaştırma yapıldı. Bulgular: Grup 1’deki hastaların ortalama gestasyonel yaşları ve doğum ağırlıkları sırasıyla 27,86±2, 0 hafta, 1,146,66±278,58 gram idi. Grup 2’deki hastaların ise ortalama gestasyonel yaşları ve doğum ağırlıkları sırasıyla 29,08±1,96 hafta, 1,289,36±74,77 gram idi. Hastaların %44’ünde retinopati saptandı ve bunların %7,1’inde ise ileri derecede retinopati geliştiği için tedavi uygulandı. Retinopati gelişen hastalarda risk faktörleri; düşük doğum haftası (p=0,007), düşük doğum ağırlığı (p=0,007), transfer edilmiş olmak (p=0,01), intraventriküler kanama (p=0,04), ventilasyon süresinin uzaması (p=0,006), oksijenin uzun süre verilmesi (p=0,001) ve kan transfüzyonu (p=0,01) istatistiksel olarak anlamlı bulundu. Sonuç: PR, dünyada çocukluk yaş grubunda en önemli körlük nedenidir. Fakat erken tanı ve uygun tedaviyle körlük önlenebilir. Bu nedenle PR risk faktörlerinin saptanması önemlidir.Introduction: Retinopathy of prematurity (ROP) is the most common cause of childhood blindness. The risk of ROP is increased in premature infants with very low birth weights, as the most common risk factors for ROP are low birth weight and early periods of gestation. The aim of this study was to evaluate the risk factors and the incidence of ROP among premature infants weighing under 1500 g upon delivery. Materials and Methods: Between August 2010 and December 2012, 84 patients followed up in the neonatal intensive care unit who were under 32 weeks old at birth and under 1500 g at birth were included in this study. Patients were separated into two groups: those with retinopathy and those without. Then the risk factors were compared between groups. Results: Mean gestational age and birth weight of the patients in group 1 and group 2 were 27.86±2.0 weeks, 1,146.66±278.58 g and 29.08±1.96 weeks, 1,289.36±74.77 g, respectively. Retinopathy was detected in 44% of the patients and of them 7.1% were treated for severe retinopathy. We determined that early periods of gestation (p=0.007), low birth weight (p=0.007), being transported (p=0.01), intraventricular hemorrhage (p=0.04), prolonged ventilation (p=0.006), prolonged oxygen administration (p=0.01), and blood transfusion (p=0.01) were statistically significant risk factors in patients with retinopathy. Conclusions: ROP has been recognized as one of the most important causes of childhood blindness in the world. However blindness is preventable if patients are diagnosed early and treated properly. Thus, it is important to determine the risk factors for ROP

Assesment of Etiology of Hyperbilirubinemic Newborn Had Exchange Transfusion

Neonatal hyperbilirubinemia is a common newborn problem and may cause important mortality and morbidity when early recognition and appropriate management was not made. In this study we aimed to asses the etiology of hyperbilirubinemia in 56 neonates who had exchange transfusion. Of patients 64% were male and 36% were female. Mean age of admission was 6.4 2.5 days and mean total bilirubin level was 3811,9 mg/dl. The cause of hyperbilirubinemia was ABO incompatibility in 34%, Rh incompatibility in 21.4%, glucose-6-phospatase deficiency in 9%, intrauterine growth restriction in 5%, sepsis in 4%, hypothyroidism in 3.6%, minor blood group incompatibility in 1.8%, cephal hematoma in 1.8%, diabetic mother’s child in 1.8% of patients. Exchange transfusion was made once in 86% and twice in 14% of patients

INFANTILE IATROGENIC CUSHING'S SYNDROME

High potency or/and extended use of topical corticosteroids, particularly in children, may cause suppression of the hypothalamopituitary-adrenal axis. However, iatrogenic Cushing's syndrome in infantile age group is very rare and only a few patients have been reported to date in the literature. Here, we report a case of iatrogenic Cushing's syndrome in a 6-month-old male child whose parents have admitted to the hospital for overweight and skin fragility

Acute hemorrhagic edema of infancy

Acute hemorrhagic edema of infancy is a rare form of leukocytoclastic vasculitis. Mostly it appears under three years of age and is characterized by purpuric skin lesions, fever and edema. A three years-old boy, who has cough and coryzea was admitted to our clinic for fever and red spots on legs and arms. In physical examination; ecimotic skin lesions on right ear, face, arms, dorsal of the hands, buttocks, legs and dorsal of the feet were found. In the laboratory tests acute phase reactants were elevated and blood coagulation tests were in normal range. Hepatit A,B,C and TORCH markers were negative. Punch biopsy obtained from gluteal area showed leukositoclastic vasculity. Focal fibrinogen accumulation was detected by immun fluorescent microscopy. Regression on lesions was not observed despite supportive therapy, so prednisolone (1 mg/kg/day) therapy was started. On the third day of the steroid therapy, complete recovery was achived