The effects of the seeds of Galeopsis ladanum on fattening performance in quails and occurrence of rhabdomyolysis in rats

This study was conducted to investigate the effect of Galeopsis ladanum seeds on rhabdomyolysis occurrence in rats as an animal model and fattening performance of quails. Control group was fed with basal diet without G. ladanum seeds. Diets of treatment groups contained 2 or 4% of G. ladanum seeds, respectively. All animals, quails and rats were fed individually. At the end of the study, 2 and 4% of G. ladanum seeds in the diets did not have reverse effect on body weight, weight gain and feed intake in quails. Besides, treatment group one had a better feed conversion ratio at the end of the third week (p<0.05) and up to 28 days of age (p<0.05). At the end of the feeding period, quails were slaughtered and their drumsticks were fed to the rats either raw or grilled. After consumption of the meat, their serum and organs were subjected to biochemical and pathologic investigations. Although, no pathological finding was observed in the tissue samples, serum myoglobin and enzyme levels were found to be higher than that in the control group (p<0.01). Although, no pathological finding was observed in the tissue samples prepared from rats and quails for histopathological examination, the increase in serum myoglobin and enzyme levels may be due to subcellular changes in the target tissues of toxic substance.Keywords: Galeopsis ladanum, performance, rhabdomyolysis, quai

The genetic history of the Southern Arc: a bridge between West Asia and Europe

By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic period and Bronze Age (about 5000 to 1000 BCE), when extensive gene flow entangled it with the Eurasian steppe. Two streams of migration transmitted Caucasus and Anatolian/Levantine ancestry northward, and the Yamnaya pastoralists, formed on the steppe, then spread southward into the Balkans and across the Caucasus into Armenia, where they left numerous patrilineal descendants. Anatolia was transformed by intra–West Asian gene flow, with negligible impact of the later Yamnaya migrations. This contrasts with all other regions where Indo-European languages were spoken, suggesting that the homeland of the Indo-Anatolian language family was in West Asia, with only secondary dispersals of non-Anatolian Indo-Europeans from the steppe

Sarcopenia in diabetic nephropathy: a cross-sectional study

Objective. To investigate the relationship between sarcopenia and diabetic nephropathy

Evaluation of coronary artery anomalies using 128-Slice computed tomography

WOS: 000306530500009Background: In this study, we aimed to investigate the efficacy of a 128-slice computed tomography (CT) device in detecting anatomical variations and anomalies of coronary arteries and to compare the results obtained with literature data. Methods: Totally, 83 patients (58 males, 25 females; mean age 53.7 +/- 10 years; range 31 to 80 years) with suspected or known coronary artery disease who underwent evaluation using the 128-slice CT in our clinic between February 2009 and December 2010 were retrospectively analyzed. All images were evaluated in terms of anatomic variation and anomaly by a radiologist with expertise in cardiovascular radiology. Continuous variables were expressed as arithmetical mean +/- standard deviation (SD), while categorical variables were expressed as percent (%). Statistical analysis was performed using descriptive statistical tests. Results: The rate of right dominance, left dominance and co-dominance was 80.7%, 8.4% and 10.8%, respectively. It was observed that the conus artery originated from the right sinus valsalva at a rate of 16.86% and from the right coronary artery (RCA) at a rate of 83.1%. It was found that sinus node artery (SNA) originated from the RCA at a rate of 77.1%, from the circumflex (Cx) artery at a rate of 18.1%, from the left main coronary artery (LMCA) at a rate of 2.4% and from the right sinus valsalva at a rate of 2.4%. Ramus intermedius was present in 30.12% of the patients. Coronary artery anomaly was observed in 48 patients (57.8%). of them, 1.2% had absence of LMCA, 6% had commissural origin, 1.2% had coronary hypoplasia, 4.8% had anomalous of contralateral sinus origin, and 43.3% had myocardial bridging. Conclusion: The 128-slice CT device is a non-invasive method which provides reliable, detailed and correct information for detecting variations and anomalies of coronary arteries. We believe that the 128-slice CT is of higher value in diagnosis and surgical therapy of coronary artery anomalies

Evaluation of correlations between nutrients, fatty acids, heavy metals, and deoxynivalenol in corn (Zea mays L.)

This study was conducted to develop linear regression equations to estimate nutrients, fatty acids, heavy metals, color characteristics (L,* a,* b*), and deoxynivalenol (DON) level of corn grains (n = 54) collected from different feed mills in Turkey. Procc corr and reg procedures were used to analyze the data. Among the nutrients, asit detergent lignin, Ca, and P had the highest variability. The heavy metal concentrations (Cd, Cr, Cu, Ni, Pb, and Zn) were lower than certain limits posted by regulation agencies for animals. Occurrence of DON was 53%, with the highest level of 0.725 ppm. Total of 32 highly significant (P < 0.01) correlations among nutrients, fatty acids, heavy metals, and color characteristics were determined in the current study. Correlations for estimating the range of parameters measured in corn from color characteristics lacked the practical importance. The correlations between C18:2 C18:1, ADF-NDF, Zn-Ca, Pb-Cu, and Pb-Cd produced the highest R (0.64 to 0.87) and R2 (0.41 to 0.74) values that would be of practical importance. The research showed that there are significant correlations among different components in corn grains that could provide necessary information to both plant breeders and feed manufacturers in the field