16 research outputs found
Fundamental physics activities with pulsed neutron at J-PARC(BL05)
"Neutron Optics and Physics (NOP/ BL05)" at MLF in J-PARC is a beamline for
studies of fundamental physics. The beamline is divided into three branches so
that different experiments can be performed in parallel. These beam branches
are being used to develop a variety of new projects. We are developing an
experimental project to measure the neutron lifetime with total uncertainty of
1 s (0.1%). The neutron lifetime is an important parameter in elementary
particle and astrophysics. Thus far, the neutron lifetime has been measured by
several groups; however, different values are obtained from different
measurement methods. This experiment is using a method with different sources
of systematic uncertainty than measurements conducted to date. We are also
developing a source of pulsed ultra-cold neutrons (UCNs) produced from a
Doppler shifter are available at the unpolarized beam branch. We are developing
a time focusing device for UCNs, a so called "rebuncher", which can increase
UCN density from a pulsed UCN source. At the low divergence beam branch, an
experiment to search an unknown intermediate force with nanometer range is
performed by measuring the angular dependence of neutron scattering by noble
gases. Finally the beamline is also used for the research and development of
optical elements and detectors. For example, a position sensitive neutron
detector that uses emulsion to achieve sub-micrometer resolution is currently
under development. We have succeeded in detecting cold and ultra-cold neutrons
using the emulsion detector.Comment: 9 pages, 5 figures, Proceedings of International Conference on
Neutron Optics (NOP2017
2経路完全分離型多層膜中性子干渉計
京都大学0048新制・課程博士博士(理学)甲第15865号理博第3606号新制||理||1526(附属図書館)28444京都大学大学院理学研究科物理学・宇宙物理学専攻(主査)教授 永江 知文, 教授 中家 剛, 教授 清水 裕彦学位規則第4条第1項該当Doctor of ScienceKyoto UniversityDA
Preparation and Characterization of Highly Fluorescent, Glutathione-coated Near Infrared Quantum Dots for in Vivo Fluorescence Imaging
Fluorescent probes that emit in the near-infrared (NIR, 700-1,300 nm) region are suitable as optical contrast agents for in vivo fluorescence imaging because of low scattering and absorption of the NIR light in tissues. Recently, NIR quantum dots (QDs) have become a new class of fluorescent materials that can be used for in vivo imaging. Compared with traditional organic fluorescent dyes, QDs have several unique advantages such as size- and composition-tunable emission, high brightness, narrow emission bands, large Stokes shifts, and high resistance to photobleaching. In this paper, we report a facile method for the preparation of highly fluorescent, water-soluble glutathione (GSH)-coated NIR QDs for in vivo imaging. GSH-coated NIR QDs (GSH-QDs) were prepared by surface modification of hydrophobic CdSeTe/CdS (core/shell) QDs. The hydrophobic surface of the CdSeTe/CdS QDs was exchanged with GSH in tetrahydrofuran-water. The resulting GSH-QDs were monodisperse particles and stable in PBS (phosphate buffered saline, pH = 7.4). The GSH-QDs (800 nm emission) were highly fluorescent in aqueous solutions (quantum yield = 22% in PBS buffer), and their hydrodynamic diameter was less than 10 nm, which is comparable to the size of proteins. The cellular uptake and viability for the GSH-QDs were examined using HeLa and HEK 293 cells. When the cells were incubated with aqueous solutions of the GSH-QDs (10 nM), the QDs were taken into the cells and distributed in the perinuclear region of both cells. After 12 hrs incubation of 4 nM of GSH-QDs, the viabilities of HeLa and HEK 293 cells were ca. 80 and 50%, respectively. As a biomedical utility of the GSH-QDs, in vivo NIRfluorescence imaging of a lymph node in a mouse is presented
Recent Progress in X-ray and Neutron Phase Imaging with Gratings
Under the JST-ERATO project in progress to develop X-ray and neutron phase-imaging methods together, recent achievements have been selected and reviewed after describing the merit and the principle of the phase imaging method. For X-ray phase imaging, recent developments of four-dimensional phase tomography and phase microscopy at SPring-8, Japan are mainly presented. For neutron phase imaging, an approach in combination with the time-of-flight method developed at J-PARC, Japan is described with the description of new Gd grating fabrication
Efficient phase imaging using wavelength-resolved neutron Talbot-Lau interferometry with TOF method
For efficient differential-phase-contrast imaging, we have demonstrated the wavelength-resolved neutron Talbot-Lau interferometry with the wavelength resolution of 0.11 Å over a wide wavelength range of 2.5–7.5 Å at RADEN in the J-PARC Materials and Life Science Experimental Facility. The time-of-flight measurement has clearly showed that the visibility of moiré fringes and intensity oscillations of the interferometer varied continuously with the wavelength, and the wavelength dependence of the differential phase of metal samples was measured. Based on the analysis utilizing this wavelength dependence, we achieved both high statistical precision and high accuracy in the differential-phase-contrast imaging, and succeeded in the quantitative evaluation of the optical potentials of metals
Relatively high rates of cefotaxime- and ceftriaxone-non-susceptible isolates among group B streptococci with reduced penicillin susceptibility (PRGBS) in Japan
Efficient phase imaging using wavelength-resolved neutron Talbot-Lau interferometry with TOF method
Square and rhombic lattices of magnetic skyrmions in a centrosymmetric binary compound
Magnetic skyrmions are topologically stable swirling spin textures with particle-like character, and have been intensively studied as a candidate of high-density information bit. While magnetic skyrmions were originally discovered in noncentrosymmetric systems with Dzyaloshinskii-Moriya interaction, recently a nanometric skyrmion lattice has also been reported for centrosymmetric rare-earth compounds, such as Gd2PdSi3 and GdRu2Si2. For the latter systems, a distinct skyrmion formation mechanism mediated by itinerant electrons has been proposed, and the search of a simpler model system allowing for a better understanding of their intricate magnetic phase diagram is highly demanded. Here, we report the discovery of square and rhombic lattices of nanometric skyrmions in a centrosymmetric binary compound EuAl4, by performing small-angle neutron and resonant elastic X-ray scattering experiments. Unlike previously reported centrosymmetric skyrmion-hosting materials, EuAl4 shows multiple-step reorientation of the fundamental magnetic modulation vector as a function of magnetic field, probably reflecting a delicate balance of associated itinerant-electron-mediated interactions. The present results demonstrate that a variety of distinctive skyrmion orders can be derived even in a simple centrosymmetric binary compound, which highlights rare-earth intermetallic systems as a promising platform to realize/control the competition of multiple topological magnetic phases in a single material. Typically, skyrmions appear in magnet systems which are non-centrosymmetric. Here, using neutron and X-ray scattering, Takagi et al show the emergence of a skyrmion phase in the centrosymmetric material EuAl4. This expands the range of materials potential hosting skyrmions