59 research outputs found

    Mathematics and German politics: The national socialist experience

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    AbstractDuring the Nazi period in Germany, an attempt was made to discern a kind of mathematics that was German as distinct from other ethnic or “racial” types of mathematics: a “Deutsche Mathematik.” While not denying the universal validity of all mathematical truths, such a “German” mathematics stressed ideology in terms of research and pedagogical styles. Because mathematics was nearly independent of anything material, it was—for the “Deutsche Mathematiker”—especially amenable to the Nazi argument that different racial psychological types exhibit different racial characters and modes of thought. This paper is a brief examination of the nature and intellectual content of “Deutsche Mathematik.

    RNAcontext: A New Method for Learning the Sequence and Structure Binding Preferences of RNA-Binding Proteins

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    Metazoan genomes encode hundreds of RNA-binding proteins (RBPs). These proteins regulate post-transcriptional gene expression and have critical roles in numerous cellular processes including mRNA splicing, export, stability and translation. Despite their ubiquity and importance, the binding preferences for most RBPs are not well characterized. In vitro and in vivo studies, using affinity selection-based approaches, have successfully identified RNA sequence associated with specific RBPs; however, it is difficult to infer RBP sequence and structural preferences without specifically designed motif finding methods. In this study, we introduce a new motif-finding method, RNAcontext, designed to elucidate RBP-specific sequence and structural preferences with greater accuracy than existing approaches. We evaluated RNAcontext on recently published in vitro and in vivo RNA affinity selected data and demonstrate that RNAcontext identifies known binding preferences for several control proteins including HuR, PTB, and Vts1p and predicts new RNA structure preferences for SF2/ASF, RBM4, FUSIP1 and SLM2. The predicted preferences for SF2/ASF are consistent with its recently reported in vivo binding sites. RNAcontext is an accurate and efficient motif finding method ideally suited for using large-scale RNA-binding affinity datasets to determine the relative binding preferences of RBPs for a wide range of RNA sequences and structures

    Gene silencing: concepts, applications, and perspectives in woody plants

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    Mathematicians under the Nazis

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    Review

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    Development of mathematics in the German Democratic Republic

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    Nine introductions in complex analysis, revised edition /

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    The book addresses many topics not usually in "second course in complex analysis" texts. It also contains multiple proofs of several central results, and it has a minor historical perspective. - Proof of Bieberbach conjecture (after DeBranges) - Material on asymptotic values - Material on Natural Boundaries - First four chapters are comprehensive introduction to entire and metomorphic functions - First chapter (Riemann Mapping Theorem) takes up where "first courses" usually leave off.The book addresses many topics not usually in "second course in complex analysis" texts. It also contains multiple proofs of several central results, and it has a minor historical perspective. - Proof of Bieberbach conjecture (after DeBranges) - Material on asymptotic values - Material on Natural Boundaries - First four chapters are comprehensive introduction to entire and metomorphic functions - First chapter (Riemann Mapping Theorem) takes up where "first courses" usually leave off.Revised edition of 1981 ed.Includes bibliographical references and index.Print version record.Elsevie
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