Research on plantar pressure dynamic distribution characteristics of samba step movements based on biomechanics

Samba dance is a factional part of sports dance. It forms a sports dance system with modern dance. According to the method of sports biomechanics experiment, the dynamic parameters and changing rules of fork foot pressure dynamic distribution characteristics are summarised, which can provide theoretical reference for further study of the basic law of samba dance. From the point of view of sports biomechanics, this paper analyses the rotation of athletes, and combines the knowledge of biomechanics with the rotation characteristics of samba dance. Studies have shown that in the comparison of general parameters, the different indicators of the foot pressure have a certain regularity in different action stages. There were no significant differences between the test group and the control group in terms of walking speed, relative speed, step size, relative step size, foot contact area time, and duration

SARS-CoV-2 in the Prostate: Immunohistochemical and Ultrastructural Studies

The novel coronavirus SARS-CoV-2 was discovered in 2019 and has proven to be a significant public health challenge. While viruses from the coronavirus family have been established as causes of respiratory tract infections, SARS-CoV-2 has also been found in the heart, kidney, testes, and penis. This paper investigates whether SARS-CoV-2 can linger in the prostate by examining the histopathological, ultrastructural, and immunofluorescent elements of prostatic tissue from a patient who was infected by the SARS-CoV-2 virus prior to having a holmium laser enucleation of the prostate (HoLEP) procedure. The findings of this case report suggest that COVID-19 has both the ability to enter prostatic tissue during an acute infection and persist over a timeframe beyond the initial infection period as RNA-containing viral bodies. This case report lays the foundation for future investigations to examine any histopathological changes to the prostatic tissue that may be associated with SARS-CoV-2 viral infection

The role of leptin and low testosterone in obesity

Obesity is a medical condition associated with metabolic disorders and low-grade systemic inflammation. Another characterizing feature of obesity is high circulating levels of leptin (a hormone predominantly made by adipose cells and enterocytes in the small intestine that helps to regulate energy balance), a phenomenon termed hyperleptinemia. Hyperleptinemia is associated with both low-grade systemic inflammation and metabolic dysfunction in obese human beings. Moreover, obesity is associated with low testosterone in men, which correlates with high body fat. The association between leptin and low testosterone could potentially be explained via the imbalanced leptin levels that results in higher estrogen levels, which further increases the aromatase activity. The increase in aromatase activity in turn reciprocally inhibits the testosterone levels and hypothalamic pituitary gonadal axis. Novel strategies are being used to treat obesity, including leptin and testosterone therapy. However, the efficacy and adverse effects of these strategies need further validation through preclinical and clinical studies. Additionally, further studies are needed to establish the molecular mechanism behind leptin-modulated changes to testosterone in obese men. This review summarizes the available literature on the role of leptin and low testosterone during obesity

Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches

Copper nanoparticles (Cu-NPs) are serious water pollutants but their impact in teleosts performance remains poorly understood. In the present study, we have exposed juvenile carps (Cyprinus carpio), a freshwater teleost edible in India to two different doses (20 and 100 μg/L) of Cu-NPs for seven days. The doses selected were eco-relevant considering the contamination levels of certain water resources. The results indicated that the activity oxidative stress enzymes catalase, superoxide dismutase, and glutathione-S-transferase were significantly increased in the kidney, liver and gills of the treated groups when compared to control. Histological analysis revealed that after exposure, disruption of the secondary lamellae of gills, liver damage with pyknotic nuclei and structural disarray of the kidney occurred. Proteomic analysis of the liver showed down-regulation of several proteins including the ferritin heavy chain, rho guanine nucleotide exchange factor 17-like, cytoglobin-1 and up-regulation of diphosphomevalonate decarboxylase and selenide & water dikinase-1. Taken together, the results of suggest that short-term exposure of juvenile carp to Cu-NPs causes oxidative stress and impart serious deleterious effects in the tissues which may affect fish growth and development