288 research outputs found

    Team Production in Business Organizations: An Introduction

    Get PDF
    For the past two decades, legal and economic scholarship has tended to assume that the central economic problem addressed by corporation law is getting managers and directors to act as faithful agents for shareholders. There are other important economic problems faced by business firms, however. This article introduces a Symposium that explores one of those alternate economic problems: the problem of team production . Team production problems can arise whenever three conditions are met: (1) economic production requires the combined inputs of two or more individuals; (2) at least some of these inputs are team-specific, meaning they have a significantly higher value when used in the team than in their next best use; and (3) the gains resulting from team production are non-separable, making it difficult to attribute any particular portion to any single team member?s contribution. In such situations, it can be difficult or impossible for team members to draft explicit contracts that protect their team-specific investments from other team members\u27 opportunism. Thus the nine articles in the Symposium explore the implications of team production analysis for a wide variety of business organizations, including public corporations, private companies, multinational firms, and venture capital firms

    Evoked and Spontaneous Pain Assessment During Tooth Pulp Injury

    Get PDF
    Injury of the tooth pulp is excruciatingly painful and yet the receptors and neural circuit mechanisms that transmit this form of pain remain poorly defined in both the clinic and preclinical rodent models. Easily quantifiable behavioral assessment in the mouse orofacial area remains a major bottleneck in uncovering molecular mechanisms that govern inflammatory pain in the tooth. In this study we sought to address this problem using the Mouse Grimace Scale and a novel approach to the application of mechanical Von Frey hair stimuli. We use a dental pulp injury model that exposes the pulp to the outside environment, a procedure we have previously shown produces inflammation. Using RNAscope technology, we demonstrate an upregulation of genes that contribute to the pain state in the trigeminal ganglia of injured mice. We found that mice with dental pulp injury have greater Mouse Grimace Scores than sham within 24 hours of injury, suggestive of spontaneous pain. We developed a scoring system of mouse refusal to determine thresholds for mechanical stimulation of the face with Von Frey filaments. This method revealed that mice with a unilateral dental injury develop bilateral mechanical allodynia that is delayed relative to the onset of spontaneous pain. This work demonstrates that tooth pain can be quantified in freely behaving mice using approaches common for other types of pain assessment. Harnessing these assays in the orofacial area during gene manipulation should assist in uncovering mechanisms for tooth pulp inflammatory pain and other forms of trigeminal pain. © 2020, The Author(s)

    Sudakov Electroweak effects in transversely polarized beams

    Full text link
    We study Standard Model electroweak radiative corrections for fully inclusive observables with polarized fermionic beams. Our calculations are relevant in view of the possibility for Next Generation Linear colliders of having transversely and/or longitudinally polarized beams. The case of initial transverse polarization is particularly interesting because of the interplay of infrared/collinear logarithms of different origins, related both to the nonabelian SU(2) and abelian U(1) sectors. The Standard model effects turn out to be in the 10% range at the TeV scale, therefore particularly relevant in order to disentangle possible New Physics effects.Comment: 5 pages,4 figure
    corecore