Shallow Triple Stream Three-dimensional CNN (STSTNet) for Micro-expression Recognition

In the recent year, state-of-the-art for facial micro-expression recognition have been significantly advanced by deep neural networks. The robustness of deep learning has yielded promising performance beyond that of traditional handcrafted approaches. Most works in literature emphasized on increasing the depth of networks and employing highly complex objective functions to learn more features. In this paper, we design a Shallow Triple Stream Three-dimensional CNN (STSTNet) that is computationally light whilst capable of extracting discriminative high level features and details of micro-expressions. The network learns from three optical flow features (i.e., optical strain, horizontal and vertical optical flow fields) computed based on the onset and apex frames of each video. Our experimental results demonstrate the effectiveness of the proposed STSTNet, which obtained an unweighted average recall rate of 0.7605 and unweighted F1-score of 0.7353 on the composite database consisting of 442 samples from the SMIC, CASME II and SAMM databases.Comment: 5 pages, 1 figure, Accepted and published in IEEE FG 201

Needle in a Haystack: Spotting and recognising micro-expressions “in the wild”

Computational research on facial micro-expressions has long focused on videos captured under constrained laboratory conditions due to the challenging elicitation process and limited samples that are publicly available. Moreover, processing micro-expressions is extremely challenging under unconstrained scenarios. This paper introduces, for the first time, a completely automatic micro-expression “spot-and-recognize” framework that is performed on in-the-wild videos, such as in poker games and political interviews. The proposed method first spots the apex frame from a video by handling head movements and unconscious actions which are typically larger in motion intensity, with alignment employed to enforce a canonical face pose. Optical flow guided features play a central role in our method: they can robustly identify the location of the apex frame, and are used to learn a shallow neural network model for emotion classification. Experimental results demonstrate the feasibility of the proposed methodology, establishing good baselines for both spotting and recognition tasks – ASR of 0.33 and F1-score of 0.6758 respectively on the MEVIEW micro-expression database. In addition, we present comprehensive qualitative and quantitative analyses to further show the effectiveness of the proposed framework, with new suggestion for an appropriate evaluation protocol. In a nutshell, this paper provides a new benchmark for apex spotting and emotion recognition in an in-the-wild setting

Cells Detection and Segmentation in ER-IHC Stained Breast Histopathology Images

In this paper, we present our recent work on cells detection and segmentation in estrogen receptor immunohistochemistry (ER-IHC)-stained breast carcinoma images. The proposed cell detection and segmentation is very useful in the predictive scoring of hormone receptor status in ER-IHC stained whole-slide images, which helps pathologists to decide whether a patient should be offered hormonal therapy or other treatments. The proposed method is based on deep convolutional neural network, followed by watershed-based post-processing. The cell detection results are compared and evaluated objectively against the ground truth provided by our collaborating pathologists. The cell segmentation results, on the other hand, are evaluated visually by overlaying the computer segmented boundaries on the ER-IHC images for comparison. The automated cell detection algorithm recorded precision and recall rates of 95% and 91% respectively. The very promising performances for both the detection and segmentation paves the way for an automated system for hormone receptor scoring in ER-IHC stained whole-slide breast carcinoma image

Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore

Because of Singapore's unique history of immigration, whole-genome sequence analysis of 4,810 Singaporeans provides a snapshot of the genetic diversity across East, Southeast, and South Asia.</p

Evaluation of prognostic risk models for postoperative pulmonary complications in adult patients undergoing major abdominal surgery: a systematic review and international external validation cohort study

Background Stratifying risk of postoperative pulmonary complications after major abdominal surgery allows clinicians to modify risk through targeted interventions and enhanced monitoring. In this study, we aimed to identify and validate prognostic models against a new consensus definition of postoperative pulmonary complications. Methods We did a systematic review and international external validation cohort study. The systematic review was done in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched MEDLINE and Embase on March 1, 2020, for articles published in English that reported on risk prediction models for postoperative pulmonary complications following abdominal surgery. External validation of existing models was done within a prospective international cohort study of adult patients (≥18 years) undergoing major abdominal surgery. Data were collected between Jan 1, 2019, and April 30, 2019, in the UK, Ireland, and Australia. Discriminative ability and prognostic accuracy summary statistics were compared between models for the 30-day postoperative pulmonary complication rate as defined by the Standardised Endpoints in Perioperative Medicine Core Outcome Measures in Perioperative and Anaesthetic Care (StEP-COMPAC). Model performance was compared using the area under the receiver operating characteristic curve (AUROCC). Findings In total, we identified 2903 records from our literature search; of which, 2514 (86·6%) unique records were screened, 121 (4·8%) of 2514 full texts were assessed for eligibility, and 29 unique prognostic models were identified. Nine (31·0%) of 29 models had score development reported only, 19 (65·5%) had undergone internal validation, and only four (13·8%) had been externally validated. Data to validate six eligible models were collected in the international external validation cohort study. Data from 11 591 patients were available, with an overall postoperative pulmonary complication rate of 7·8% (n=903). None of the six models showed good discrimination (defined as AUROCC ≥0·70) for identifying postoperative pulmonary complications, with the Assess Respiratory Risk in Surgical Patients in Catalonia score showing the best discrimination (AUROCC 0·700 [95% CI 0·683–0·717]). Interpretation In the pre-COVID-19 pandemic data, variability in the risk of pulmonary complications (StEP-COMPAC definition) following major abdominal surgery was poorly described by existing prognostication tools. To improve surgical safety during the COVID-19 pandemic recovery and beyond, novel risk stratification tools are required. Funding British Journal of Surgery Society