Discussion of "Impact of Frequentist and Bayesian Methods on Survey Sampling Practice: A Selective Appraisal" by J. N. K. Rao

This comment emphasizes the importance of model checking and model fitting when making inferences about finite population quantities. It also suggests the value of using unit level models when making inferences for small subpopulations, that is, "small area" analyses [arXiv:1108.2356].Comment: Published in at http://dx.doi.org/10.1214/11-STS346B the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics (http://www.imstat.org

Functional data analytic approach of modeling ECG T-wave shape to measure cardiovascular behavior

The T-wave of an electrocardiogram (ECG) represents the ventricular repolarization that is critical in restoration of the heart muscle to a pre-contractile state prior to the next beat. Alterations in the T-wave reflect various cardiac conditions; and links between abnormal (prolonged) ventricular repolarization and malignant arrhythmias have been documented. Cardiac safety testing prior to approval of any new drug currently relies on two points of the ECG waveform: onset of the Q-wave and termination of the T-wave; and only a few beats are measured. Using functional data analysis, a statistical approach extracts a common shape for each subject (reference curve) from a sequence of beats, and then models the deviation of each curve in the sequence from that reference curve as a four-dimensional vector. The representation can be used to distinguish differences between beats or to model shape changes in a subject's T-wave over time. This model provides physically interpretable parameters characterizing T-wave shape, and is robust to the determination of the endpoint of the T-wave. Thus, this dimension reduction methodology offers the strong potential for definition of more robust and more informative biomarkers of cardiac abnormalities than the QT (or QT corrected) interval in current use.Comment: Published in at http://dx.doi.org/10.1214/09-AOAS273 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org

About item response theory models and how they work

This article is about FMCSA data and its analysis. The article responds to the two-part question: How does an Item Response Theory (IRT) model work differently . . . or better than any other model? The response to the first part is a careful, completely non-technical exposition of the fundamentals for IRT models. It differentiates IRT models from other models by providing the rationale underlying IRT modeling and by using graphs to illustrate two key properties for data items. The response to the second part of the question about superiority of an IRT model is, “it depends.” For FMCSA data, serious challenges arise from complexity of the data and from heterogeneity of the carrier industry. Questions are posed that will need to be addressed to determine the success of the actual model developed and of the scoring system

Tree-Based Methods: A Tool for Modeling Nonlinear Complex Relationships and Generating New Insights from Data

Our paper introduces tree-based methods, specifically classification and regression trees (CRT), to study student achievement. CRT allows data analysis to be driven by the data’s internal structure. Thus, CRT can model complex nonlinear relationships and supplement traditional hypothesis-testing approaches to provide a fuller picture of the topic being studied. Using Early Childhood Longitudinal Study-Kindergarten 2011 data as a case study, our research investigated predictors from students’ demographic backgrounds to ascertain their relationships to students’ academic performance and achievement gains in reading and math. In our study, CRT displays complex patterns between predictors and outcomes; more specifically, the patterns illuminated by the regression trees differ across the subject areas (i.e., reading and math) and between the performance levels and achievement gains. Through the use of real-world assessment datasets, this article demonstrates the strengths and limitations of CRT when analyzing student achievement data as well as the challenges. When achievement data such as achievement gains in our case study are not linearly strongly related to any continuous predictors, regression trees may make more accurate predictions than general linear models and produce results that are easier to interpret. Our study illustrates scenarios when CRT on achievement data is most appropriate and beneficial

A Case Study of Nonresponse Bias Analysis

Nonresponse bias is a widely prevalent problem for data collections. We develop a ten-step exemplar to guide nonresponse bias analysis (NRBA) in cross-sectional studies, and apply these steps to the Early Childhood Longitudinal Study, Kindergarten Class of 2010-11. A key step is the construction of indices of nonresponse bias based on proxy pattern-mixture models for survey variables of interest. A novel feature is to characterize the strength of evidence about nonresponse bias contained in these indices, based on the strength of relationship of the characteristics in the nonresponse adjustment with the key survey variables. Our NRBA incorporates missing at random and missing not at random mechanisms, and all analyses can be done straightforwardly with standard statistical software