Tomanek Hall: Letter, to Sandy Rupp, from Doug Sebelius, August 4, 1995

Mr. Sebelius enclosed a picture of his parents, Keith and Bette, and offered to give remarks at the dedication ceremony for Tomanek Hall and the Keith G. Sebelius Lobby in the place of his mother.https://scholars.fhsu.edu/tomanek/1065/thumbnail.jp

100 Questions About Sturgis

Exploring my own identity and voice within diverse subcultures has become essential in my current artistic practice and process. My aim is to visually explore lived experience amongst culturally rich communities, without judgment or expectations. I recently returned from the 71st Annual Sturgis Motorcycle Rally in South Dakota, which had an attendance of 600,000 riders. In an effort to immerse myself in the biker culture, I camped out for seven days at the rally. The constant rumble of motorcycles has faded from my ears but remain in my mind unsettlingly. After this experience I was left with a mind full of imagery but an intellect filled with questions. My most recent work investigates my connection and exploration of this masculine culture and the individuals I lived amongst

Gasbedövning av gris inför slakt

I Sverige är det lagstadgat att djur skall vara bedövade innan de slaktas. Att upprätthålla en god djurvälfärd i slaktsituationen är inte enbart en grundpelare i vår svenska djurskyddslag, utan även en ständigt aktuell fråga som engagerar både livsmedelsproducenter likväl som konsumenter. Bedövning av grisar utförs i stor utsträckning med hjälp av koldioxid. Denna metod är vida omdiskuterad och ofta ifrågasatt ur djurvälfärdsaspekt. Detta då gasen är erkänt aversiv för djurslaget ifråga. Bedövning med koldioxid är dock billigt och tidseffektivt, vilket är en bidragande anledning till att gasen fortfarande används på svenska slakterier. Denna litteraturstudie syftar till att titta närmare på vilka alternativ som finns till dagens användande av koldioxid samt spegla vilka för- och nackdelar som finns med dessa gaser. Gaserna har framförallt bedömts utifrån djurvälfärdsperspektiv men hänsyn har även tagits till hur väl de fungerar ur produktionshänseende. Argon och mixturer av Ar/CO2 har utmärkt sig som ett djurvänligt alternativ till koldioxid samt visat på god förmåga att upprätthålla en jämn koncentration inne i schaktet. Kväve och N2/CO2-mixturer har i studier visat sig vara mindre aversiva än ren CO2 och grisarna upplever inte heller samma känsla av andnöd vid exponering för kvävemixturer. Negativt med dessa är dock att induktionstiden är längre samt att bedövningskvaliteten är sämre. Nya studier på området bekräftar att grisar uppvisar aversivt beteende i form av flyktförsök och flämtningar vid CO2-koncentrationer ner till 15 %, vilket omkullkastar tidigare teorier om att endast koncentrationer högre än 30 % ger upphov till aversion hos djuren. Ett annat alternativ till koldioxid är helium där resultatet från en nyligen publicerad studie indikerar att denna gas är mindre aversiv samt mer djurvänlig i jämförelse med koldioxid. Dessvärre finns det få studier publicerade på området, vilket i dagsläget gör det svårt att dra några konkluderande slutsatser utifrån resultaten. För att underlätta ett framtida användande av lätta gaser samt minimera grisarnas lidande i slaktsituationen skulle en omkonstruktion av slakterierna och ny teknik i bedövningssystemen vara eftersträvansvärt. Exempelvis har försök med administrering av gaser i en tvåstegsprocedur med argon som första steg och koldioxid som andra steg visat sig fungera väl. Användande av ett sådant system skulle troligen gynna grisarna och bidra till en bättre djurvälfärd i slaktsituationen. Sammanfattningsvis konstateras att det både finns aspekter som talar för, men även emot ett eventuellt användande av alternativa gaser i framtiden. I dagsläget finns det dock ingen självklar lösning på problematiken kring hur man på bästa sätt bedövar grisar inför slakt.According to Swedish law, animals must be stunned prior to slaughter. To uphold a sufficient animal welfare during the process of slaughtering is not only a focal point in the law but also of great importance for food producers and consumers. Stunning of pigs is most commonly performed using carbon dioxide. This method is widely debated and often questioned from an animal welfare point of view, since the gas has shown to be aversive. However, stunning pigs with carbon dioxide is both time – and cost effective, which are the main reasons to why it is still used in Swedish abattoirs. The aim of this literature study is to further evaluate alternative gas mixtures as potential substitutes for carbon dioxide in the stunning procedure. Advantages and disadvantages are discussed for each mixture respectively as well as when compared to carbon dioxide. The gases are primarily evaluated from an animal welfare point of view but considerations has also been taken to whether they are suitable to different production systems and if they could fulfill occupational safety requirements. Argon has distinguished itself as an animal -friendly alternative to carbon dioxide. Mixtures of Ar/CO2 have also shown satisfying results. Experimental studies have presented that the advantages of nitrogen and N2/CO2-mixtures are few, and the disadvantages are many. Pigs proved higher rate of gasping and retreat- and escape attempts when exposed to N2/CO2-mixtures compared to argon. On the other hand, time to loss of consciousness has been proven to be lower when pigs are exposed to N2/CO2-mixtures. Making use of gases in a two-step procedure, preferably with argon as a first step and carbon dioxide as a second (to induce deeper unconsciousness) has shown to be a more functional way of administrating gases. The use of such a stunning-system would probably benefit the pigs and improve animal welfare prior to slaughter. Helium and carbon monoxide may also work as potential substitutes to carbon dioxide. A German study from 2013 indicated that helium seemed to be less aversive than carbon dioxide. Unfortunately only a few studies have been reported regarding this gas, which makes the results difficult to evaluate. In conclusion; studies regarding alternative gas mixtures indicate that there are both advantages- and disadvantages to take into consideration, and there is no obvious solution to this complicated problem

En enkelblindad, prospektiv, randomiserad pilotstudie för att utvärdera behandlingseffekten av KalvatinTM vid intertrigo hos hund.

Bakteriell hudinfektion (pyodermi), är ett av de vanligaste dermatologiska besvären hos våra sällskapshundar. Pyodermier delas in i yt, ytliga och djupa beroende på infektionsdjup och allvarlighetsgrad. En sorts yt-pyodermi är veckdermatit (intertrigo), vilken vanligen uppstår i täta hudveck, till exempel hos hundar med brachycefal ansiktsform. Preparatet KalvatinTM Dermal Gel, framtaget av Enzymatica AB, skulle potentiellt kunna utgöra en alternativ behandlingsmetod för yt-pyodermier hos hund. KalvatinTM innehåller köldanpassat trypsin som inom humanvården har visat sig ha inflammationsdämpande och läkningsfrämjande egenskaper. Den trypsininnehållande gelen bildar en tunn beläggning på hudens ytskikt och hämmar mikroorganismer från att adherera. KalvatinTM är helt fritt från antibiotika och selekterar därmed inte för resistensutveckling hos bakterier. Syftet med denna prospektiva, randomiserade och enkelblindade studie är att utvärdera om KalvatinTM Dermal Gel är effektiv för att behandla mikrobiell intertrigo hos hund. I studien inkluderades totalt tjugo stycken privatägda hundar med nosvecksdermatit. Hundarna undersöktes kliniskt och evaluerades cytologiskt dag 0, dag 7 och dag 14 i studien. Behandling utfördes med ett så kallat split-body protokoll, där höger respektive vänster nosveck randomiserat behandlades med KalvatinTM Dermal Gel två gånger dagligen, alternativt fungerade som obehandlad kontroll under studieperioden. Vid inklusion i studien (dag 0) förelåg ingen signifikant skillnad P = 0,78 emellan hudområdena i de olika behandlingsgrupperna, varken i kliniskt eller cytologiskt score. Inklusionsdata bedömdes vara normalfördelad och analyserades med hjälp av ett parat t-test. Vid studieavslut (dag 14) kunde en signifikant skillnad mellan behandlad och obehandlad sida påvisas P = 0.0021. Det var endast ett fåtal hundar som bedömdes vara helt utläkta vid studieavslut. Detta gällde oavsett om hudvecket blivit behandlat med KalvatinTM Dermal Gel eller inte. Inom gruppen som hade behandlats med KalvatinTM bedömdes 10 % vara utläkta vid avslutad behandling och i den obehandlade gruppen bedömdes 5 % som utläkta vid studieavslut. Denna kliniska pilotstudie indikerar att KalvatinTM Dermal Gel potentiellt skulle kunna användas som profylaktisk behandling av lindrig intertrigo hos hund, men vidare studier bör göras och då inkludera ett större urval av hundar samt en längre behandlingsperiod.Bacterial skin infection (pyoderma), is one of the most common dermatological diseases among companion dogs. Pyoderma can be divided into surface, superficial and deep, depending on infection depth and severity. Surface pyoderma is the mildest form of bacterial infection of the skin, which simply means a colonization of the outer layer, stratum corneum. Skinfold dermatitis is a surface pyoderma caused by an inflamation due to frictional trauma of skin rubbing against skin. Pugs, English - and French bulldogs are predisposed to develop skinfold dermatitis, due to their brachycephalic anatomy with deep nasal skinfolds. KalvatinTM Dermal Gel, developed by Enzymatica AB, could potentially provide an alternative treatment method for surface pyoderma in dogs. KalvatinTM contains cold adapted trypsin and have anti-inflammatory and healing promoting properties. KalvatinTM form a thin coating on the skin surface and inhibits microorganisms from adhere. KalvatinTM is free of antibiotics, hence it selects no development of resistance in bacteria. The aim of the study was to evaluate if KalvatinTM Dermal Gel is effective for treatment of surface pyoderma and malasezzia dermatitis in dogs. Twenty pet dogs with facial fold dermatitis was included in the trial, which was performed prospective, randomized and blinded. The dogs were each examined three times during the study, at day 0, 7 and 14. Dogs with a minimum clinical lesion score at 1 and a presence of at least 5-10 bacteria or malassezia/5HPF was included in the study and were randomly assigned to treat the right or the left nasal skin fold, while the other skinfold was left untreated. At day 0 there was no significant difference P = 0.78 between the skin areas in the different treatment groups, either in clinical or cytologically score. Data was analyzed using a paired t- test. At the end of the study, day 14, a significant difference between treated and untreated side could be detected as P = 0.0021. It was only a few dogs that were assessed to be completely healed when the end of the study. In the group treated with KalvatinTM, only 10 % were completely healed at the end of treatment. In the untreated group only 5 % were healed at day 14. In conclusion this pilot study indicates that KalvatinTM Dermal Gel potentially could be used as a prophylactic treatment of mild intertrigo in dogs. However, it is recommended to conduct further studies with a greater variety of dogs included, as well as a longer treatment period

Design and technical construction of a tactile display for sensory feedback in a hand prosthesis system

<p>Abstract</p> <p>Background</p> <p>The users of today's commercial prosthetic hands are not given any conscious sensory feedback. To overcome this deficiency in prosthetic hands we have recently proposed a sensory feedback system utilising a "tactile display" on the remaining amputation residual limb acting as man-machine interface. Our system uses the recorded pressure in a hand prosthesis and feeds back this pressure onto the forearm skin. Here we describe the design and technical solution of the sensory feedback system aimed at hand prostheses for trans-radial/humeral amputees. Critical parameters for the sensory feedback system were investigated.</p> <p>Methods</p> <p>A sensory feedback system consisting of five actuators, control electronics and a test application running on a computer has been designed and built. Firstly, we investigate which force levels were applied to the forearm skin of the user while operating the sensory feedback system. Secondly, we study if the proposed system could be used together with a myoelectric control system. The displacement of the skin caused by the sensory feedback system would generate artefacts in the recorded myoelectric signals. Accordingly, EMG recordings were performed and an analysis of the these are included. The sensory feedback system was also preliminarily evaluated in a laboratory setting on two healthy non-amputated test subjects with a computer generating the stimuli, with regards to spatial resolution and force discrimination.</p> <p>Results</p> <p>We showed that the sensory feedback system generated approximately proportional force to the angle of control. The system can be used together with a myoelectric system as the artefacts, generated by the actuators, were easily removed using a simple filter. Furthermore, the application of the system on two test subjects showed that they were able to discriminate tactile sensation with regards to spatial resolution and level of force.</p> <p>Conclusions</p> <p>The results of these initial experiments in non-amputees indicate that the proposed tactile display, in its simple form, can be used to relocate tactile input from an artificial hand to the forearm and that the system can coexist with a myoelectric control systems. The proposed system may be a valuable addition to users of myoelectric prosthesis providing conscious sensory feedback during manipulation of objects.</p

SmartVista: Smart Autonomous Multi Modal Sensors for Vital Signs Monitoring

Cardiovascular diseases (CVD) remain the leading cause of mortality and a major cause of morbidity in Europe. Every year there are more than 6 million new cases of CVD in the EU and more than 11 million in Europe as a whole. With almost 49 million people living with the disease in the EU, the cost to the EU economies is 210 billion EUR a year. There is a growing demand for a reliable cardiac monitoring system to catch the intermittent abnormalities and detect critical cardiac behaviours which, in extreme cases, can lead to sudden death. The objective of the Smart Autonomous Multi Modal Sensors for Vital Signs Monitoring (SmartVista) project is to develop and demonstrate a next generation, cost-effective, smart multimodal sensing platform to reduce incidences of sudden death caused by CVD, and will contribute to the EU vision of an Internet of Things for healthcare. The key innovation in SmartVista is to integrate 1D/2D nanomaterials based sensors to monitor the heart, thermoelectric energy harvesters to extract energy from the body to power the system and printable battery systems to store this energy. Together these will result in a self-powered device that will autonomously monitor the electrocardiograph, respiratory flow, oxygen flow and temperature of the patient. This information will then be transmitted wirelessly for online health processing. This real-time self-powered monitoring of a patient's health is currently not available. Thus, the technology that will be developed in SmartVista will position us at the forefront of digital health and wearable biosensor technology for wireless monitoring in hospitals and of remote patients, both of which are necessary in this era of an aging population

Combinations of School-Based Primary and Secondary Preventive Dental Programs in the United States and Other Countries

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65940/1/j.1752-7325.1979.tb02953.x.pd