The effect of fluoride on enamel and dentin formation in the uremic rat incisor

Renal impairment in children is associated with tooth defects that include enamel pitting and hypoplasia. However, the specific effects of uremia on tooth formation are not known. In this study, we used rat mandibular incisors, which continuously erupt and contain all stages of tooth formation, to characterize the effects of uremia on tooth formation. We also tested the hypothesis that uremia aggravates the fluoride (F)-induced changes in developing teeth. Rats were subjected to a two-stage 5/6 nephrectomy or sham operation and then exposed to 0 (control) or 50 ppm NaF in drinking water for 14 days. The effects of these treatments on food intake, body growth rate, and biochemical serum parameters for renal function and calcium metabolism were monitored. Nephrectomy reduced food intake and weight gain. Intake of F by nephrectomized rats increased plasma F levels twofold and further decreased food intake and body weight gain. Uremia affected formation of dentin and enamel and was more extensive than the effect of F alone. Uremia also significantly increased predentin width and induced deposition of large amounts of osteodentin-like matrix-containing cells in the pulp chamber. In enamel formation, the cells most sensitive to uremia were the transitional-stage ameloblasts. These data demonstrate that intake of F by rats with reduced renal function impairs F clearance from the plasma and aggravates the already negative effects of uremia on incisor tooth development

La radiografia digitale in Reumatologia.

Il testo è dedicato alla descrizione dei quadri radiologici osservabili in corso delle diverse malattie reumatiche. Vengono esaminate tutte le malattie e riportati i quadri morfologici caratteristici. Una particolare attenzione è dedicata agli aspetti diagnostico differenziali. Le implicazioni, i vantaggi e la versatilità della nuova tecnologia digitale vengono illustrate nel dettaglio

CASE-REPORT 375 - DIAGNOSIS - MULTICENTRIC RETICULOHISTIOCYTOSIS

A case of MR in a 18-years old girl is presented with dramatic demonstration of the progressive lesions of the hands demonstrated by xerography

Il quadro radiologico delle alterazioni muscolo-scheletriche nell’insufficienza renale cronica. Imaging of musculo-skeletal manifestations associated with chronic renal insufficiency.

Le alterazioni muscolo-scheletriche in corso di insufficienza renale cronica sono molteplici. Le alterazioni radiologiche più frequenti (osteodistrofia renale) sono correlate all'iperparatiroidismo secondario, all'osteoporosi, all'osteomalacia. si possono riscontrare lesioni correlate al trapianto ed al trattamento dialitico

L'osteoartrosi erosiva: radiologia convenzionale versus radiologia digitale.

Il lavoro analizza il quadro radiologico dell'artrosi erosiva e valuta vantaggi e limiti della radiologia digitale rispetto alla radiografia convenzional

Reabsorption of the mandible in systemic sclerosis

Case report e rassegna sintetica sul riassorbimento osseo in corso di sclerosi sistemic

Il follow-up radiologico dell’osteoartrosi erosiva.

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Il quadro radiologico della mano e del piede nel lupus Eritematoso Sistemico

A detailed examination of the hands and feet was performed in a group of 34 patients affected by systemic lupus erythematosus (SLE), using low-dose mammographic film and Rank Xerox selenium plate, according to current diagnostic techniques. All patients presented articular symptoms (pain and arthralgia). The high incidence (38,8\%) of patients with no radiographic evidence of bone damage-even though articular symptoms are present-is emphasized. In such cases, it is very difficult to distinguish SLE from rheumatoid arthritis, especially as far as therapeutic management and prognosis are concerned. The lack of any "pathognomonic" radiological sign of the lupus arthritis, in the hands as well as in the feet, is then stressed. Nevertheless, arthropathy in SLE is defined as a deforming non-erosive arthritis, with a typical symmetric distribution, affecting most commonly-according to incidence-the proximal interphalangeal and metacarpophalangeal joints. In the hand, arthropathy is referred to as Jaccoud's type arthritis, because it is characterized by joint deformities which can be corrected. In the foot, the main abnormalities include hallux valgus, subluxation of the metatarsophalangeal joints and widening of the forefoot