108 research outputs found

    Newspapermen can be made

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    Thesis (M.S.)--Boston Universit

    Measuring Stellar Radial Velocities with a Dispersed Fixed-Delay Interferometer

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    We demonstrate the ability to measure precise stellar barycentric radial velocities with the dispersed fixed-delay interferometer technique using the Exoplanet Tracker (ET), an instrument primarily designed for precision differential Doppler velocity measurements using this technique. Our barycentric radial velocities, derived from observations taken at the KPNO 2.1 meter telescope, differ from those of Nidever et al. by 0.047 km/s (rms) when simultaneous iodine calibration is used, and by 0.120 km/s (rms) without simultaneous iodine calibration. Our results effectively show that a Michelson interferometer coupled to a spectrograph allows precise measurements of barycentric radial velocities even at a modest spectral resolution of R ~ 5100. A multi-object version of the ET instrument capable of observing ~500 stars per night is being used at the Sloan 2.5 m telescope at Apache Point Observatory for the Multi-object APO Radial Velocity Exoplanet Large-area Survey (MARVELS), a wide-field radial velocity survey for extrasolar planets around TYCHO-2 stars in the magnitude range 7.6<V<12. In addition to precise differential velocities, this survey will also yield precise barycentric radial velocities for many thousands of stars using the data analysis techniques reported here. Such a large kinematic survey at high velocity precision will be useful in identifying the signature of accretion events in the Milky Way and understanding local stellar kinematics in addition to discovering exoplanets, brown dwarfs and spectroscopic binaries.Comment: 9 pages, 4 figures. Accepted for publication in Ap

    High Energy Colliders as Black Hole Factories: The End of Short Distance Physics

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    If the fundamental Planck scale is of order a TeV, as the case in some extra-dimensions scenarios, future hadron colliders such as the Large Hadron Collider will be black hole factories. The non-perturbative process of black hole formation and decay by Hawking evaporation gives rise to spectacular events with up to many dozens of relatively hard jets and leptons, with a characteristic ratio of hadronic to leptonic activity of roughly 5:1. The total transverse energy of such events is typically a sizeable fraction of the beam energy. Perturbative hard scattering processes at energies well above the Planck scale are cloaked behind a horizon, thus limiting the ability to probe short distances. The high energy black hole cross section grows with energy at a rate determined by the dimensionality and geometry of the extra dimensions. This dependence therefore probes the extra dimensions at distances larger than the Planck scale.Comment: Latex, 28 pages. v4: minor changes, largely to agree with published version; appendix added comparing convention

    The importance of quantum decoherence in brain processes

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    Based on a calculation of neural decoherence rates, we argue that that the degrees of freedom of the human brain that relate to cognitive processes should be thought of as a classical rather than quantum system, i.e., that there is nothing fundamentally wrong with the current classical approach to neural network simulations. We find that the decoherence timescales ~10^{-13}-10^{-20} seconds are typically much shorter than the relevant dynamical timescales (~0.001-0.1 seconds), both for regular neuron firing and for kink-like polarization excitations in microtubules. This conclusion disagrees with suggestions by Penrose and others that the brain acts as a quantum computer, and that quantum coherence is related to consciousness in a fundamental way.Comment: Minor changes to match accepted PRE version. 15 pages with 5 figs included. Color figures and links at http://www.physics.upenn.edu/~max/brain.html or from [email protected]. Physical Review E, in pres

    Family medicine graduates' perceptions of intimidation, harassment, and discrimination during residency training

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    <p>Abstract</p> <p>Background</p> <p>Despite there being considerable literature documenting learner distress and perceptions of mistreatment in medical education settings, these concerns have not been explored in-depth in Canadian family medicine residency programs. The purpose of the study was to examine intimidation, harassment and/or discrimination (IHD) as reported by Alberta family medicine graduates during their two-year residency program.</p> <p>Methods</p> <p>A retrospective questionnaire survey was conducted of all (n = 377) family medicine graduates from the University of Alberta and University of Calgary who completed residency training during 2001-2005. The frequency, type, source, and perceived basis of IHD were examined by gender, age, and Canadian vs international medical graduate. Descriptive data analysis (frequency, crosstabs), Chi-square, Fisher's Exact test, analysis of variance, and logistic regression were used as appropriate.</p> <p>Results</p> <p>Of 377 graduates, 242 (64.2%) responded to the survey, with 44.7% reporting they had experienced IHD while a resident. The most frequent type of IHD experienced was in the form of inappropriate verbal comments (94.3%), followed by work as punishment (27.6%). The main sources of IHD were specialist physicians (77.1%), hospital nurses (54.3%), specialty residents (45.7%), and patients (35.2%). The primary basis for IHD was perceived to be gender (26.7%), followed by ethnicity (16.2%), and culture (9.5%). A significantly greater proportion of males (38.6%) than females (20.0%) experienced IHD in the form of work as punishment. While a similar proportion of Canadian (46.1%) and international medical graduates (IMGs) (41.0%) experienced IHD, a significantly greater proportion of IMGs perceived ethnicity, culture, or language to be the basis of IHD.</p> <p>Conclusions</p> <p>Perceptions of IHD are prevalent among family medicine graduates. Residency programs should explicitly recognize and robustly address all IHD concerns.</p

    Does the Committee Peer Review Select the Best Applicants for Funding? An Investigation of the Selection Process for Two European Molecular Biology Organization Programmes

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    Does peer review fulfill its declared objective of identifying the best science and the best scientists? In order to answer this question we analyzed the Long-Term Fellowship and the Young Investigator programmes of the European Molecular Biology Organization. Both programmes aim to identify and support the best post doctoral fellows and young group leaders in the life sciences. We checked the association between the selection decisions and the scientific performance of the applicants. Our study involved publication and citation data for 668 applicants to the Long-Term Fellowship programme from the year 1998 (130 approved, 538 rejected) and 297 applicants to the Young Investigator programme (39 approved and 258 rejected applicants) from the years 2001 and 2002. If quantity and impact of research publications are used as a criterion for scientific achievement, the results of (zero-truncated) negative binomial models show that the peer review process indeed selects scientists who perform on a higher level than the rejected ones subsequent to application. We determined the extent of errors due to over-estimation (type I errors) and under-estimation (type 2 errors) of future scientific performance. Our statistical analyses point out that between 26% and 48% of the decisions made to award or reject an application show one of both error types. Even though for a part of the applicants, the selection committee did not correctly estimate the applicant's future performance, the results show a statistically significant association between selection decisions and the applicants' scientific achievements, if quantity and impact of research publications are used as a criterion for scientific achievement

    Distributed Drug Discovery, Part 2: Global Rehearsal of Alkylating Agents for the Synthesis of Resin-Bound Unnatural Amino Acids and Virtual D3 Catalog Construction

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    Distributed Drug Discovery, Part 1: Linking Academia and Combinatorial Chemistry to Find Drug Leads for Developing World Diseases

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