Are bank employees stressed? job perception and positivity in the banking sector: an italian observational study

Background: The epidemiology of stress on bank workers in Europe is only at the introductory stages. This study investigated for the first time the association between occupational stress level in bank-employees using the BEST8, Karasek-Model and socio-demographic and working factors in Italy. Methods: The observational pilot study involved 384 employees. Three questionnaires were adopted to collect data: Karasek-Model, BEST8 (p < 0.001) and Positivity-Scale. Results: 25% of the sample belonged to high stress group. The workers more stressed were older with a commercial role and consumer of antidepressants/sedatives. Women were much more likely to agree with the perception of feeling unsafe in a possible robbery (OR = 2.42; 95% CI: 1.50-3.91) and with that sales requests were in conflict with one's own personal moral code (OR = 2.31; 95% CI: 1.38-3.87). Older employees declared feeling inadequate in the workplace (OR = 1.97; 95% CI: 1.07-3.65) and younger employees referred to be anxious about meeting financial budget goals. Workers who had a low positivity had a lower probability of adaptation (OR = 0.88; 95% CI: 0.83-0.93). Conclusions: The occupational stress level in the banking sector involves many aspects: gender, type of bank, role, personal morals, high job-demands, low level of decision-making. This study recommended that banks should implement strategic interventions for well-being of employees, and consequently for their productivity

Trends in integration of photovoltaic facilities into the built environment

Cities are consumers of large amounts of energy. They require uninterrupted energy supply but with dynamic power profile.Mainly consumption of energy generated from fossil fuels is present todaywith consequence significant pollution of the environment.The sustainable energy transition in cities means increasing the supply of energy from renewable sources.Thepaperpoints to the integration of PV renewable systems in the built environment, opportunities and constraints, design conditions and tools. The consideration of the constraints which creates urban environment is carried out in order to understand the complexity of selecting locations in the cities. In thissense, the paper gives an overview of the possibilitiesof PV systemsintegration in the built environment, and discusses physical limitations in the urban environment and simulation toolsas well as challenges and research and development issues

Projektovanje solarnih sistema za arhitektonske objekte i BIM alati - pregled relevantnih geometrijskih aspekata

The paper systematizes geometric aspects relevant for understanding design of solar systems. The systematization is based on a review of literature dedicated to various kinds of engineers, including architects, involved in a multidisciplinary process of conceptualizing, designing and realization of PV systems. The understanding of the presented geometric aspects, known as solar geometry, is important not only in terms of finding optimal orientation and most effective tilt of solar modules, but also in terms of adequate geometric modelling of façade elements of a complex shape (as specific photovoltaic modules) in order to be optimally exposed to the sun all over the year. After providing detailed explanations of the main elements of solar geometry using the tools of spherical trigonometry, the paper discusses the integration of the presented geometric concepts in the BIM environments, and refers the example of Autodesk Revit software through its sun study tool. Analysed are functionalities of all interactive components of the 3D solar path representation. A need for more explicit determination of an incidence angle of the sun rays on a tilted surface is stressed. In the conclusion highlighted is the essential knowledge on solar geometry that needs to be acquired during architectural education, so that architects participating in the BIM working environments could be prepared for efficient conceptualization of integrated solar systems.U radu su sistematizovani najvažniji geometrijski aspekti koji su relevantni za celovito razumevanje projektovanja fotonaponskih sistema. Ova sistematizacija se bazira na pregledu literature namenjene različitim inženjerima, uključujući arhitekte koji su uključeni u multidisciplinarne procese konceptualizacije, projektovanja i realizacije fotonaponskih sistema. Razumevanje prikazanih geometrijskih aspekata, u literaturi objedinjenih pod nazivom solarna geometrija, značajno je ne samo zbog pronalaženja optimalne orijentacije i najefektnijeg nagiba fotonaponskih modula, nego i zbog adekvatnog oblikovanja geometrijski kompleksnih fasadnih elemenata, koji bi trebalo da budu optimalno osunčani tokom cele godine. Nakon detaljnog objašnjenja osnovnih elemenata solarne geometrije korišćenjem sferne trigonometrije, u radu je prodiskutovana integracija prikazanih geometrijskih koncepata u BIM okruženja, ilustrovana primerom modula za analize osunčanja u okviru softvera Revit, firme Autodesk. Analizirana je funkcionalnost svih interaktivnih komponenata 3D prikaza sunčeve putanje. Naglašena je potreba za eksplicitnijim određivanjem upadnog ugla sunčevih zraka na nagnutu površ fotonaponskog modula. U zaključnom delu izdvojeno je ono znanje o solarnoj geometriji koje bi bilo neophodno usvojiti u procesu arhitektonskog obrazovanja, kako bi projektanti koji rade u BIM okruženju bili pripremljeni za efikasnu konceptualizaciju integrisanih fotonaponskih sistema

Antagonizing S1P3 receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis

Bioactive lipids, derived from the metabolism of plasma membrane, are important mediators of cellular signaling in vertebrates. In recent years there has been a growing interest on sphingosine-1-phosphate (S1P) which is the final metabolite produced during the sequential degradation of plasma membrane glycosphingolipids and sphingomyelin. The S1P acts through five known subtypes of heptameric G-protein coupled receptors (GPCR), namely S1P1-S1P5 (S1PR). Recent evidence indicates that S1P signaling axis contributes to the development and maintenance of the fibrotic process [1]. Fibrosis is a pathological condition that can affect every organ, consequence of a persisting inflammatory and tissue remodeling condition. In different fibrotic models an extensive crosstalk between TGFβ and S1P signaling axis has been demonstrated. S1P3 plays a pivotal role in fibrosis development in different tissues such as skeletal muscle, liver, and kidney [2]. Thus, selective antagonists of the S1P3 receptor could be useful to deeply study its role in fibrosis as well as to develop new therapeutic entities to treat fibrotic diseases. Pepducins specifically target the intracellular loops, acting as allosteric modulators of GPCR activity. Using this approach, we have synthesized a pepducin based S1P3 antagonist namely KRX-725-II (Myristoyl-GRPYDAN-NH2) [3]. Here to improve the S1P1 vs S1P3 selectivity, we have synthesized several derivatives of KRX-725-II pointing our attention on the aromatic residue of the sequence, Tyr4, and with the aim to introduce molecular constraints. The new molecular entities have been evaluated for their selectivity profile by using mouse aortas. This screening allowed us to identify compounds V and VII (embodying respectively L- and D-Tic) as the most selective S1P3 antagonists. The selected compounds also displayed the ability to significantly reduce the profibrotic action of TGFβ1 in C2C12 myoblasts. To explain the higher selectivity observed for compounds V and VII, they were analyzed by Molecular Dynamics (MD) Simulations. The middle conformations of V and VII were compared by superimposing their GRP residues, which adopt a similar backbone orientation (see Figure). This revealed that the DAN residues with β-turn-like motif are located on opposite sides of the plane defined by the L- or D-Tic residue. This difference may explain, in structural terms, the selective S1P3 antagonism of V and VII in comparison to the unselective antagonist KRX-725-II, whose flexibility seems to be high enough for the adaptation to the binding regions of the individual receptor subtypes S1P1 and S1P3. Peptides V and VII possess, indeed, a highly constrained D- or L-Tic residue that hinder the pharmacophore from interacting properly with the binding pocket of the S1P1 receptor, therefore leading to S1P3 selectivity

Designing photovoltaic systems for architectural integration

This document is addressed to manufacturers of photovoltaic systems. It describes the main criteria for a successful integration of PV systems in buildings and proposes a methodology for the design of systems specifically conceived for building integration. For each specific sub-technology, it provides a comprehensive set of practical recommendations that should lead to the production of new systems appealing to architects

Product developments and dissemination activities

This document shows product developments and dissemination activities carried out within the framework of, or in close relation to, the project IEA SHC Task 41; Solar Energy and Architecture. This Task gathered researchers and practicing architects from 14 countries in the three year project whose aim was to identify the obstacles architects are facing when incorporating solar design in their projects, to provide resources for overcoming these barriers and to help improving architects’ communication with other stakeholders in the design of solar buildings. Participating countries were Australia, Austria, Belgium, Canada, Denmark, Germany, Italy, Norway, Portugal, Republic of Korea, Singapore, Spain, Sweden and Switzerland. The report gives not a complete list of activities, but shows the different types of activities to spread the findings in Task 41 and to initiate product developments in participating countries

Bollettino Sismico Italiano: Analisys of Early Aftershocks of the 2016 MW 6.0 Amatrice, MW 5.9 Visso and MW 6.5 Norcia earthquakes in Central Italy

The Amatrice-Visso-Norcia seismic sequence is the most important of the last 30 years in Italy. The seismic sequence started on 24 August, 2016 and still is ongoing in central Apennines. At the end of February 2017 more than 57,000 events were located, 80,000 events up to the end of September 2017 (Fig. 1). The mainshocks of the sequence occurred on 24 August 2016 (Mw 6.0 and Mw 5.4), 26 October 2016 (Mw 5.4 and Mw 5.9), 30 October 2016 (Mw 6.5), 18 January 2017 (four earthquakes Mw≥ 5.0). In this seismic sequence, all the waveforms recorded by temporary stations deployed by the SISMIKO emergency group (stations T12**; Moretti et al., 2016) where available in real- time at the surveillance room of INGV. Because of the high level of seismicity and the dense seismic network installed in the region, more than 150 events per day were located at the end of February 2017; still 60 events per day were located up to the end of August 2017.The Amatrice-Visso-Norcia is the most important seismic sequence since 2015, the time when the analysis procedures of the BSI group (Bollettino Sismico Italiano) were revised (Nardi et al., 2015). BSI is now available every four months on the web: bulletins contain revised earthquakes (location and magnitude) with ML≥ 1.5, quasi-real time revision of ML≥ 3.5 earthquakes and phase arrivals from waveforms recorded on seismic stations available from the European Integrated Data Archive (EIDA), (Mazza et al., 2012). These last procedures allow the integration of signals from temporary seismic stations (Moretti et al., 2014) installed by the emergency group SISMIKO (Moretti and Sismiko working group, 2016), even when they are not in real time transmission, if they are rapidly archived in EIDA, together with real time signals from the seismic stations of the permanent INGV network. The analysis strategy of the BSI group for the Amatrice -Visso - Norcia seismic sequence (AVN.s.s in the following) was to select the earthquakes located in the box with min/max latitude: 42.2/43.2 - and min/max longitude: 12.4/14.1 to prepare a special volume of BSI on the seismic sequence.PublishedTrieste, Italy1SR. TERREMOTI - Servizi e ricerca per la Societ

Bollettino Sismico Italiano gennaio – aprile 2019

Nel periodo che va dal 1 gennaio al 30 aprile 2019, gli analisti del BSI hanno revisionato tutti gli eventi di magnitudo M≥1.5, mentre i parametri dei terremoti di magnitudo inferiore a tale soglia di revisione sono stati calcolati in tempo reale, nella sala di sorveglianza sismica di Roma.Istituto Nazionale di Geofisica e Vulcanologia - Dipartimento di Protezione CivilePublished4IT. Banche dat