A precise determination of alpha_s from LEP thrust data using effective field theory

Starting from a factorization theorem in Soft-Collinear Effective Theory, the thrust distribution in e+e- collisions is calculated including resummation of the next-to-next-to-next-to leading logarithms. This is a significant improvement over previous calculations which were only valid to next-to-leading logarithmic order. The fixed-order expansion of the resummed result approaches the exact fixed-order distribution towards the kinematic endpoint. This close agreement provides a verification of both the effective field theory expression and recently completed next-to-next-to-leading fixed order event shapes. The resummed distribution is then matched to fixed order, resulting in a distribution valid over a large range of thrust. A fit to ALEPH and OPAL data from LEP 1 and LEP 2 produces alpha_s(m_Z)= 0.1172 +/- 0.0010 +/- 0.0008 +/-0.0012 +/- 0.0012, where the uncertainties are respectively statistical, systematic, hadronic, and perturbative. This is one of the world's most precise extractions of alpha_s to date.Comment: 37 pages, 12 figures; v2: hadronization discussion and appendices expande

Precision direct photon and W-boson spectra at high p_T and comparison to LHC data

The differential p_T spectrum for vector boson production is computed at next-to-leading fixed order and including the resummation of threshold logarithms at next-to-next-to-leading logarithmic accuracy. A comparison is made to ATLAS data on direct photon and W production at high transverse momentum p_T, finding excellent agreement. The resummation is achieved by factorizing contributions associated with different scales using Soft-Collinear Effective Theory. Each part is then calculated perturbatively and the individual contributions are combined using renormalization group methods. A key advantage of the effective theory framework is that it indicates a set of natural scale choices, in contrast to the fixed-order calculation. Resummation of logarithms of ratios of these scales leads to better agreement with data and reduced theoretical uncertainties.Comment: 24 pages, 10 figures; v2: journal version; v3: corrections in (20), (37), (38

Generalized Colonel Blotto Game

Competitive resource allocation between adversarial decision makers arises in a wide spectrum of real-world applications such as in communication systems, cyber-physical systems security, as well as financial, political, and electoral competition. As such, developing analytical tools to model and analyze competitive resource allocation is crucial for devising optimal allocation strategies and anticipating the potential outcomes of the competition. To this end, the Colonel Blotto game is one of the most popular game-theoretic frameworks for modeling and analyzing such competitive resource allocation problems. However, in many real-world competitive situations, the Colonel Blotto game does not admit solutions in deterministic strategies and, hence, one must rely on analytically complex mixed-strategies with their associated tractability, applicability, and practicality challenges. In this paper, a generalization of the Colonel Blotto game which enables the derivation of deterministic, practical, and implementable equilibrium strategies is proposed while accounting for the heterogeneity of the battlefields. In addition, the proposed generalized game enables accounting for the consumed resources in each battlefield, a feature that is not considered in the classical Blotto game. For the generalized game, the existence of a Nash equilibrium in pure-strategies is shown. Then, closed-form analytical expressions of the equilibrium strategies, are derived and the outcome of the game is characterized; based on the number of resources of each player as well as the valuation of each battlefield. The generated results provide invaluable insights on the outcome of the competition. For example, the results show that, when both players are fully rational, the more resourceful player can achieve a better total payoff at the Nash equilibrium, a result that is not mimicked in the classical Blotto game.Comment: 8 pages, 5 figure

The Structure Inventory of the Nuclear Pore Complex

The nuclear pore complex (NPC) is the principal gateway for molecular exchange between nucleus and cytoplasm across the nuclear envelope. Due to its sheer size of estimated 50-112 MDa and its complex buildup from about 500-1000 individual proteins, it is a difficult object to study for structural biologists. Here, I review the extensive ensemble of high-resolution structures of the building blocks of the NPC. Concurrent with the increase in size and complexity, these latest, large structures and assemblies can now be used as the basis for hybrid approaches, primarily in combination with cryo-electron microscopic analysis, generating the first structure-based assembly models of the NPC. Going forward, the structures will be critically important for a detailed analysis of the NPC, including function, evolution, and assembly. Keywords: macromolecular complexes; nuclear pore complexNational Institutes of Health (U.S.) (Grant GM077537

Parametric investigation of soft-body penetration into parallel-ridged textured surfaces for tactile applications

The tribological interactions between skin and textured surfaces has profound impact on both the tactile perception of the product being used, as well as the functionality of the product with regards to friction coefficient. Previous work has shown that parallel-ridged textures have vastly different friction coefficients with regards to the direction of skin sliding, and that penetration of the skin into the voids between ridges not only add contact area but also potential for interlocking. The ability to model skin penetration into textural elements would prove to be very useful for predicting friction; however, the mechanics of the problem are incredibly complex such that they rule out a closed-form analytical solution. The authors investigated soft-body penetration using a non-dimensional computational approach based on the elastic properties of skin, as well as the texture ridge geometry parameters, as well as the normal loading. Model results were verified experimentally. The model was applied to a number of different combinations of ridge parameters and it was found that the amount of penetration could be predicted very well using a simple exponential relationship among the nondimensional terms. Texture groove width and applied normal load played a dominant role in penetration. These results yield a quantitative mechanics model which can be integrated into an overarching frictional model to predict skin on texture behavior due to both adhesion and edge interlocking

A Study of the Relationship Between the Ideological Tendencies of United States Supreme Court Cases Affecting the Press, 1946-1974

Analysis of United States Supreme Court decision-making in cases affecting the press is important to communication law because many significant aspects of the court’s political behavior cannot be studied by reading the opinions of the court. The great volume of cases and range of issues simply preclude meaningful analysis except when subjected to the quantitative techniques of data processing and measurement. The hypotheses are: 1. Basic attitudes of Supreme Court justices contribute to their voting behavior. 2. Basic attitudes of Supreme Court justices in civil liberties cases. 3. Basic attitudes of Supreme Court justices toward press issues contribute to their voting behavior in press cases

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms

Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic viruses have been implicated in the induction of malignant lymphomas in their hosts. BLV causes enzootic bovine leukosis in infected cattle or sheep. During the past few years several new Deltaretrovirus isolates have been described in various primate species. Two new HTLV-like viruses in humans have recently been identified and provisionally termed HTLV-III and HTLV-IV. In order to identify a broad spectrum of Deltaretroviruses by a single PCR approach we have established a novel consensus PCR based on nucleotide sequence data obtained from 42 complete virus isolates (HTLV-I/-II, STLV-I/-II/-III, BLV). The primer sequences were based on highly interspecies-conserved virus genome regions. We used this PCR to detect Deltaretroviruses in samples from adult patients with a variety of rare T-cell neoplasms in Germany. Results: The sensitivity of the consensus PCR was at least between 10-2 and 10-3 with 100% specificity as demonstrated by serial dilutions of cell lines infected with either HTLV-I, HTLV-II or BLV. Fifty acute T-cell lymphoblastic leukemia (T-ALL) samples and 33 samples from patients with various rare mature T-cell neoplasms (T-PLL, Sezary syndrome and other T-NHL) were subsequently investigated. There were no cases with HTLV-I, HTLV-II or any other Deltaretroviruses. Conclusions: The results rule out a significant involvement of HTLV-I or HTLV-II in these disease entities and show that other related Deltaretroviruses are not likely to be involved. The newly established Deltaretrovirus PCR may be a useful tool for identifying new Deltaretroviruses

Structural and Functional Studies of the 252 kDa Nucleoporin ELYS Reveal Distinct Roles for Its Three Tethered Domains

In metazoa, the nuclear envelope (NE), together with the embedded nuclear pore complexes (NPCs), breaks down and reassembles during cell division. It is suggested that ELYS, a nucleoporin, binds to chromatin in an initial step of postmitotic NPC assembly and subsequently recruits the essential Y-subcomplex, the major scaffolding unit of the NPC. Here, we show that ELYS contains three domains: an N-terminal β-propeller domain, a central α-helical domain, and a C-terminal disordered region. While the disordered region is responsible for the interactions with chromatin, the two preceding domains synergistically mediate tethering to the NPC. We present the crystal structure of the seven-bladed β-propeller domain at 1.9 Å resolution. Analysis of the β-propeller surface reveals the regions that are required for NPC anchorage. We discuss the possible roles of ELYS in the context of the NPC scaffold architecture.National Institutes of Health (U.S.) (Grant GM077537