74 research outputs found
Analyse und Optimierung des Verfahrens Tropfbewässerung im ökologischen Feldgemüsebau – mit Schwerpunkt auf Arbeitswirtschaft und Wassereffizienz
Die Tropfbewässerung für Freilandgemüsekulturen im ökologischen Landbau ist mit wirtschaftlichen und technischen Herausforderungen verbunden. Das Verfahren bietet ausreichend Optimierungspotential. Es werden technische Entwicklungs- und praktische Managementhilfen für Erzeuger benötigt
Waiting for Precise Measurements of K^+->pi^+ nu nu and K_L->pi^0 nu nu
In view of future plans for accurate measurements of the theoretically clean
branching ratios Br(K+ -> pi+ nu nu) and Br(KL -> pi0 nu nu), that should take
place in the next decade, we collect the relevant formulae for quantities of
interest and analyze their theoretical and parametric uncertainties. We point
out that in addition to the angle beta in the unitarity triangle (UT) also the
angle gamma can in principle be determined from these decays with respectable
precision and emphasize in this context the importance of the recent NNLO QCD
calculation of the charm contribution to K+ -> pi+ nu nu and of the improved
estimate of the long distance contribution by means of chiral perturbation
theory. In addition to known expressions we present several new ones that
should allow transparent tests of the Standard Model (SM) and of its
extensions. While our presentation is centered around the SM, we also discuss
models with minimal flavour violation and scenarios with new complex phases in
decay amplitudes and meson mixing. We give a brief review of existing results
within specific extensions of the SM, in particular the Littlest Higgs Model
with T-parity, Z' models, the MSSM and a model with one universal extra
dimension. We derive a new "golden" relation between B and K systems that
involves (beta,gamma) and Br(KL -> pi0 nu nu) and investigate the virtues of
(R_t,beta), (R_b,gamma), (beta,gamma) and (etabar,gamma) strategies for the UT
in the context of K -> pi nu nu decays with the goal of testing the SM and its
extensions.Comment: 56 pages, 18 figures, Section on Long Distance Contributions, 2
Figures and few References added, Uses Rev Mod Phys Style; Includes new
results of NNLO calculation as well as matrix elements, extended and modified
sections on new physic
Adjuvant therapy for children treated by enucleation at diagnosis of retinoblastoma
Introduction
Advanced localized retinoblastoma can be cured by enucleation, but extraocular spread of retinoblastoma cells is associated with a high mortality. Risk-stratified adjuvant treatment with chemotherapy and radiotherapy has been shown to reduce the risk for extraocular relapse in children with histopathological risk factors.
Methods
Data of 184 patients with retinoblastoma and primary enucleation were collected in a prospective, multicenter, observational study between 2013 and 2020. The clinical characteristics were evaluated as risk factors and progression-free and overall survival rates were compared.
Results
Seventy-one percent of 184 children with retinoblastoma treated with primary enucleation were diagnosed with low risk histopathological factors (pT1/pT2a) and received no adjuvant therapy. Children with intermediate risk (pT2b,pT3; 48 children, 26.0%) and high risk for metastasis (pT4; 5 children, 2.7%) received risk-stratified adjuvant treatment. None of the children with low risk or intermediate risk (pT1-pT3) relapsed, but two of five children with high-risk retinoblastoma (pT4) developed extraocular relapses and one deceased. The 2-year progression-free survival rate and 2-year overall survival rate was 100% for children with pT1-3 retinoblastoma. However, the 2-year progression-free survival rate and 2-year overall survival rate for children with pT4 was statistically notably reduced with 2 of 5 children developing progression and 1 death among the 5 children within 2 years after diagnosis.
Conclusion
Primary enucleation alone and with additional risk-stratified adjuvant chemotherapy treatment provides high cure rates in patients with pT1-3 retinoblastoma, but children with pT4 retinoblastoma remain at high risk to develop extraocular retinoblastoma. International prospective clinical trials are required to evaluate reduction of intensity of adjuvant chemotherapy in some risk groups (pT2, pT3) and intensification for pT4 retinoblastoma
Potential of Core-Collapse Supernova Neutrino Detection at JUNO
JUNO is an underground neutrino observatory under construction in Jiangmen, China. It uses 20kton liquid scintillator as target, which enables it to detect supernova burst neutrinos of a large statistics for the next galactic core-collapse supernova (CCSN) and also pre-supernova neutrinos from the nearby CCSN progenitors. All flavors of supernova burst neutrinos can be detected by JUNO via several interaction channels, including inverse beta decay, elastic scattering on electron and proton, interactions on C12 nuclei, etc. This retains the possibility for JUNO to reconstruct the energy spectra of supernova burst neutrinos of all flavors. The real time monitoring systems based on FPGA and DAQ are under development in JUNO, which allow prompt alert and trigger-less data acquisition of CCSN events. The alert performances of both monitoring systems have been thoroughly studied using simulations. Moreover, once a CCSN is tagged, the system can give fast characterizations, such as directionality and light curve
Detection of the Diffuse Supernova Neutrino Background with JUNO
As an underground multi-purpose neutrino detector with 20 kton liquid scintillator, Jiangmen Underground Neutrino Observatory (JUNO) is competitive with and complementary to the water-Cherenkov detectors on the search for the diffuse supernova neutrino background (DSNB). Typical supernova models predict 2-4 events per year within the optimal observation window in the JUNO detector. The dominant background is from the neutral-current (NC) interaction of atmospheric neutrinos with 12C nuclei, which surpasses the DSNB by more than one order of magnitude. We evaluated the systematic uncertainty of NC background from the spread of a variety of data-driven models and further developed a method to determine NC background within 15\% with {\it{in}} {\it{situ}} measurements after ten years of running. Besides, the NC-like backgrounds can be effectively suppressed by the intrinsic pulse-shape discrimination (PSD) capabilities of liquid scintillators. In this talk, I will present in detail the improvements on NC background uncertainty evaluation, PSD discriminator development, and finally, the potential of DSNB sensitivity in JUNO
Real-time Monitoring for the Next Core-Collapse Supernova in JUNO
Core-collapse supernova (CCSN) is one of the most energetic astrophysical
events in the Universe. The early and prompt detection of neutrinos before
(pre-SN) and during the SN burst is a unique opportunity to realize the
multi-messenger observation of the CCSN events. In this work, we describe the
monitoring concept and present the sensitivity of the system to the pre-SN and
SN neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO), which is
a 20 kton liquid scintillator detector under construction in South China. The
real-time monitoring system is designed with both the prompt monitors on the
electronic board and online monitors at the data acquisition stage, in order to
ensure both the alert speed and alert coverage of progenitor stars. By assuming
a false alert rate of 1 per year, this monitoring system can be sensitive to
the pre-SN neutrinos up to the distance of about 1.6 (0.9) kpc and SN neutrinos
up to about 370 (360) kpc for a progenitor mass of 30 for the case
of normal (inverted) mass ordering. The pointing ability of the CCSN is
evaluated by using the accumulated event anisotropy of the inverse beta decay
interactions from pre-SN or SN neutrinos, which, along with the early alert,
can play important roles for the followup multi-messenger observations of the
next Galactic or nearby extragalactic CCSN.Comment: 24 pages, 9 figure
Estudo do desempenho dos materiais de demarcação viária retrorrefletivos.
Neste trabalho foram avaliados o desempenho, quanto à retrorrefletância e desgaste, de diversos materiais utilizados em demarcação viária, implantados em campo, sob condições de tráfego conhecidas. Foi também desenvolvido o equipamento e uma metodologia para aplicação, com ancoragem controlada, dos materiais de demarcação viária em laboratório. Esta metodologia foi utilizada para se estabelecer taxas ideais de aplicação de microesferas de vidro em relação à retrorrefletividade inicial. Os materiais foram caracterizados de acordo com os padrões nacionais. Foram propostos novos procedimentos para medidas de retrorrefletância e desgaste dos materiais no campo. À partir dos dados de campo, foram propostos valores mínimos aceitáveis de retrorrefletividade inicial, desgaste e retrorrefletividade final dos materiais, abaixo dos quais recomenda-se a manutenção dos sistemas de demarcação viária. Finalmente, foram estabelecidas relações de custos/benefício entre os diversos materiais utilizados na sinalização horizontal em rodovias brasileiras.In this work, it was evaluated the performance, regarding to retroreflectivity and wear of several road marking materials, applied on a test field of known traffic conditions. It was also developed a device and methodology for the application of glass beads on road marking paints under controlled embedment, in laboratory. This methodology was used to established the correlations between rates (g/m2) of glass beads and initial retroreflectivity. The materials were chacterized according to the brazilian standards. It was proposed new standard procedures for measurement of retroreflectivity and wear of applied road marking materials. Based on field and laboratory studies, it was proposed minimal acceptance values for initial retroreflectivity and minimal values for final retroreflectivity and wear of road markings, when the maintenance of the system is recommended. Finally, it was established the relationship between cost and benefit of the various road marking materials, used on horizontal signalization on the brazilian roads
Does Diglossia Impact Brain Structure? Data from Swiss German Early Diglossic Speakers.
(1) Background: Bilingualism has been reported to shape the brain by inducing cortical changes in cortical and subcortical language and executive networks. Similar yet different to bilingualism, diglossia is common in Switzerland, where the German-speaking population switches between an everyday spoken Swiss German (CH-GER) dialect and the standard German (stGER) used for reading and writing. However, no data are available for diglossia, defined as the use of different varieties or dialects of the same language, regarding brain structure. The aim of our study is to investigate if the presence of this type of diglossia has an impact on the brain structure, similar to the effects seen in bilingualism. (2) Methods: T1-weighted anatomical MRI scans of participants were used to compare the grey matter density and grey matter volume of 22 early diglossic CH-GER-speaking and 20 non-diglossic French-speaking right-handed university students, matched for age, linguistics and academic background. The images were processed with Statistical Parametric Mapping SPM12 and analyzed via voxel- and surface-based morphometry. (3) Results: A Bayesian ANCOVA on the whole brain revealed no differences between the groups. Also, for the five regions of interest (i.e., planum temporale, caudate nucleus, ACC, DLPFC and left interior parietal lobule), no differences in the cortical volume or thickness were found using the same statistical approach. (4) Conclusion: The results of this study may suggest that early diglossia does not shape the brain structure in the same manner as bilingualism
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