BRASH Syndrome Case Report and Brief Review

BRASH syndrome is an acronym that stands for bradycardia, renal failure, AV node blocker, shock and hyperkalemia. The syndrome is precipitated by synergism from AV nodal blocking agents and hyperkalemia. The combination of the AV nodal blockade and renal failure leads to a cycle of severe bradycardia and hyperkalemia. We will discuss a case of BRASH syndrome with a 68 year old female who presented with generalized weakness and was found to be hypotensive, bradycardia, in acute renal failure with hyperkalemia likely related to metoprolol and amlodipine use

Long-Term Neurocognitive Effects of Treatment for Pediatric Lymphoid Malignancies

Kaspers, G.J.L. [Promotor]Sonneville, L.M.J. de [Copromotor]Bos, C. van den [Copromotor

Diffusion Analysis of the Emerging Market for Low Emission Vehicles

Non peer reviewedPostprin

Effects of revenue use and perceived effectiveness on acceptability of transport pricing policies

Car use causes various collective problems, such congestion and increasing CO2-emmisions. One way to manage these problems is to influence people’s car use. Pricing policies aimed at making car use more expensive, such as implementing congestion or kilometre charges, may be effective strategies to influence people’s car use. However, significant pricing policies are not easily implemented, since they are not acceptable to the public. Acceptability levels may dependent on the type of pricing policy being implemented. In this study we examined two policy characteristics that may affect the acceptability of pricing policies: revenue use and price level. It is hypothesised that pricing policies are more acceptable if price increases are rather low, and if revenues benefit individual car users rather than the general public. Further, we examined the relationship between policy acceptability and effectiveness. On the one hand we assume that policies are not acceptable if they are not effective in changing people’s car use. In that case, people experience the disadvantages of the policies while at the same time problems resulting from car use, such as congestion, are not being solved. On the other hand, policies that are very effective in changing one’s own car use are probably also not acceptable, because this seriously threatens people’s freedom to move. Thus, we hypothesise policies are acceptable if they reduce the problems of car use, without seriously affecting people’s own car use and freedom of choice.

Virtue and happiness: a philosophical inquiry

A Research Report submitted to the Faculty of Humanities, University of the Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Master of Arts, Applied Ethics for Professionals University of the Witwatersrand, Johannesburg, 16th March 2015The position that holds that virtue, as a good, is sufficient for happiness has had illustrious exponents in the past. We will refer to this position as the sufficiency thesis. In recent times however this position has fallen into disfavour. This is largely due to the strong intuition that certain goods other than virtue are necessary for happiness. We will refer to this as the problem of external goods. The point of this paper is to respond to the problem of external goods by articulating an understanding of virtue as involving the ability to occupy a “distanced perspective” within which the virtuous agent becomes detached from external goods insofar as he comes to view them as indifferent. My articulation of this understanding of virtue will be based upon what I take to be the core of the Stoic description of virtue

Stercoral Colitis Leading to Hypotension and IVC Syndrome with Respiratory Failure Following Fecal Disimpaction

Constipation is an extremely common chief complaint in the emergency department, contributing to approximately 700,000 emergency department visits in 2011. Severe constipation can result in stercoral colitis, which in turn can lead to development of ulceration and colonic perforation leading to fatal peritonitis. As a result, prompt recognition and treatment of this condition with bowel cleansing and fecal disimpaction are often recommended. Here, we will discuss a case of a 62-year-old male with a history of schizoaffective disorder who came into the Emergency Department (ED) hypotensive with stercoral colitis secondary to severe constipation. Following bedside fecal disimpaction, the patient developed sudden respiratory failure and required emergent intubation