14 research outputs found

    Gas holdup and longitudinal dispersion in different types of multiphase reactors and their possible application for microbial processes

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    Gas holdup and liq. phase longitudinal dispersion were detd. in concurrent 1- and 6-stage, 2-phase bubble columns, and in countercurrent 1-stage, 2- and 3-phase bubble columns, using the longitudinal dispersion and backflow cell models to describe the intensity of longitudinal mixing. The axial dispersion model in conjuction with Monod growth kinetics were used to examine the influence of fluid mixing on the performance of a microbial process. [on SciFinder (R)

    Entwicklung von Testmethoden und -systemen fuer die Prozessanalytik in der Biotechnologie Abschlussbericht

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    For the testing and comparison of biotechnical equipments and measuring systems three bioprocesses have been developed and applied as model systems: yeast production by saccharomyces creoisiae, production of subbilisin Carlsberg alkaline serine by Bacillus licheniformic, and the cultivation of Cephalosporium acremonium. Measuring methods and devices have been adapted to the biological systems, and software have been developed for dynamic and static device characterization. Cultivation medium composition, e.g. starch, maltose, glucose, urea, ammonia, phosphate concentrations and protease activity were monitored by on-line and off-line multi-channel flow injection analysis. In a case study, a hybrid model of yeast production processes has been developed combining mathematical models, neural networks and fuzzy rules. (WEN)SIGLEAvailable from TIB Hannover: F95B1612 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekArbeitsgemeinschaft Industrieller Forschungsvereinigungen e.V., Koeln (Germany)DEGerman

    Analyse komplexer Produktgasgemische aus der Wirbelschichtverbrennung ballastreicher Braunkohle

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    Vortrag auf dem NOx-Kolloquium des Instituts fuer Technische Chemie der Universitaet Hannover und der Fa. Kontron Analytik GmbH, Muenchen in HannoverTIB: AC 6718+MF / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

    Charakterisierung, Modellierung und adaptive Regelung von Wirbelschichtfeuerungsanlagen im Technikumsmassstab Abschlussbericht

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    With 9 refs., 42 figs.Copy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman

    Entwicklung und Anwendung von Biosensoren in der Biotechnologie Nr. 5 Schlussbericht (Broschuere)

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    State of the art: Biosensores have been developed, but seldom applied in the biotechnology. Aim: Development of reliable biosensors and their application in the biotechnological practice. Method: Following sensors have been developed, tested and applied for process monitoring: pH- and fluoride sensitive field effect transistors (pH-FET, pF-FETs) and oxygen sensitive optodes. Heterogeneous affinity sensors were developed as well as applied for monitoring process variables in animal cell cultivations. Animal cell cultivation processes were optimized by these sensors. Knowledge-based fault detection and diagnosis systems were developed. Results: The optodes, PH-FETs, pF-FETs and affinity sensors were applied for monitoring of cultivations with bacteria, yeasts, fungi and animal cells with success. By means of the process monitoring the productivity of the blood factor AT III was improved. Another pH-(DLC)-, pO_2-, phosphate-, and H_2O_2-sensitive ISFET- and EIS-sensors were developed as well. Conclusions/applications: The biosensors developed in the frame of this project have been used for off-line and on-line process monitoring with success. They are suitable for bioprocess monitoring in laboratories and pilot plants. A company was founded for the commercialisation of the oxygen-optode. (orig.)Available from TIB Hannover: F97B689 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman
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