Anwendung von Open Educational Resources bei Hochschullehrenden. Gestaltungsoptionen und Unterstützungsmöglichkeiten

Das Hauptanliegen von Open Educational Resources (OER) ist es, digitale Lehr- und Lernmaterialien frei zugänglich und ohne Einschränkungen nutzbar zu machen, woraus sich Potenziale für die digitale Bildungslandschaft ergeben. Voraussetzung hierfür sind neben der Auffindbarkeit und Verfügbarkeit von geeigneten Materialien, Möglichkeiten Inhalte kollaborativ zu erstehen und auszutauschen. Dieser Beitrag beschäftigt sich ausgehend von dem Nutzungsverhalten von Hochschuhehrenden mit der Frage, welche Erwartungen und Anforderungen diese Zielgruppe an technische OERInfrastrukturen hat und welche Bedarfe zur Unterstützung bei der Anwendung von OER bestehen. Hierfür wurde eine Interviewstudie mit Hochschullehrenden über ihre praktischen Erfahrungen bei der Arbeit mit OER durchgeführt, insbesondere bei der Erstellung, Nutzung und Bearbeitung von Lehr- und Lernmaterialien. Aus diesen Ergebnissen konnten Gestaltungsoptionen und Unterstützungsmöglichkeiten abgeleitet werden. (DIPF/Orig.

Practices of Higher Education Teachers in Dealing with Open Educational Resources: Presentation and Promotion of Application Types

Open Educational Resources (OER) ermöglichen, digitale Lehr- und Lernmaterialien frei verfügbar und ohne Einschränkungen nutzbar zu machen. Daher haben OER grosses Potenzial, Lehre kollaborativ zu gestalten und zu entwickeln. Um die Nutzung von OER zu fördern und Hochschulehrende im Umgang mit OER unterstützen, ist es wichtig, auf deren Bedürfnisse und Anforderungen einzugehen. Dafür sind detaillierte Einblicke in Praktiken und Verhalten der Lehrenden bei der Verwendung und Überarbeitung von Materialien notwendig. In diesem Beitrag werden Ergebnisse eines Forschungsprojekts vorgestellt, welches Nutzungsverhalten von OER durch Hochschullehrende identifiziert. Methodisch wurde eine Interviewstudie mit Hochschullehrenden über ihre praktischen Erfahrungen bei der Arbeit mit OER durchgeführt. Auf dieser Basis wurden Anwendungstypen abgeleitet, die sich auf die OER-Aktivitäten bei der Erstellung, Nutzung, Bearbeitung und Veröffentlichung von Materialien beziehen. Hieraus konnten Optionen bei der Gestaltung von OER-Infrastrukturen und Unterstützungsmöglichkeiten für deren Nutzung ermittelt werden.Open Educational Resources (OER) enable digital teaching and learning materials to be made freely available and usable without restrictions. Therefore, OER have great potential that teaching can be designed and developed collaboratively. In order to increase the use of OER and support higher education teachers in their use of OER, it is important to address their needs and requirements. For this, detailed insights into practices and behaviours of teachers in the use and revision of materials are necessary. This paper presents the results of a research project that identifies the usage behaviour of OER by university teachers. For this purpose, an interview study with higher education teachers about their practical experiences in working with OER was conducted. On this basis, application types were derived that relate to OER activities in the creation, use, editing and publication of materials. From this, options in the design of OER infrastructures and support options for their use could be identified

Malformations of the sacculus and the semicircular canals in spider morph pythons

Spider morph ball pythons are a frequently-bred designer morph with striking alterations of the skin color pattern. We created high-resolution μCT-image series through the otic region of the skulls, used 3D-reconstruction software for rendering anatomical models, and compared the anatomy of the semicircular ducts, sacculus and ampullae of wildtype Python regius (ball python) with spider morph snakes. All spider morph snakes showed the wobble condition (i.e., twisting movements of the head, impaired locomotion, difficulty striking or constricting prey items). We describe the inner ear structures in wildtype and spider morph snakes and report a deviant morphology of semicircular canals, ampullae and sacculus in the latter. We also report about associated differences in the desmal skull bones of spider morph snakes, which were characterized by wider semicircular canals, ampullae widened and difficult to discern in μCT, a deformed crus communis, and a small sacculus with a highly deviant X-ray morphology as compared to wildtype individuals. We observed considerable intra- and interindividual variability of these features. This deviant morphology in spider morph snakes could easily be associated with an impairment of sense of equilibrium and the observed neurological wobble condition. Limitations in sample size prevent statistical analyses, but the anatomical evidence is strong enough to support an association between the wobble condition and a malformation of the inner ear structures. A link between artificially selected alterations in pattern and specific color design with neural-crest associated developmental malformations of the statoacoustic organ as known from other vertebrates is discussed

DELIKAT – Fachdialoge Deliberative Demokratie: Analyse Partizipativer Verfahren für den Transformationsprozess

Das Projekt erfasst und bewertet die Potenziale existierender Partizipationsformate für die Transformation des politischen Systems zu einer kooperativen und deliberativen Demokratie. Angestrebt wird kein Alternativentwurf zu einer repräsentativen Demokratie, sondern Empfehlungen für eine Ergänzung dieser Regierungsform durch kooperative und deliberative Elemente, die der gesellschaftlichen Forderung nach einem „Mehr an Beteiligung“ Rechnung tragen. Den Hintergrund für die theoretische Reflexion bildet die normative Annahme, dass die Öffentlichkeit nicht nur an Wahlprozessen beteiligt sein soll, sondern auch an der Entscheidungsvorbereitung und der Abwägung von kollektiv verbindlichen Handlungsoptionen, von deren Konsequenzen sie in ihrem Lebensumfeld betroffen sein werden. Anhand der Ergebnisse des Projektes ergeben sich Anknüpfungspunkte für zukünftige Vorhaben auf zwei Ebenen. Die Partizipationsmatrix bietet auf der Verfahrensebene gute Möglichkeiten zur Kombination und Rekombination einzelner Verfahren wie auch Verfahrensbestandteile. Die Politikempfehlungen zeigen weitergehend konkrete Wege für die Umsetzung einer neuen Partizipationskultur durch Politik und Verwaltung im Sinne eines neuen Mainstreamings von Partizipation. Diese sprechen sich im Kern dafür aus, mehr Beteiligung zu wagen, ja, eine „Kultur der Beteiligung“ zu etablieren. Diese ist jedoch an Voraussetzungen gebunden, die ebenso aufgeführt werden. Der institutionelle Unterbau einer solchen Beteiligungskultur wird letztlich in einem Mainstreaming von Partizipation auf allen Ebenen von Politik und Verwaltung lokalisiert.The project detects and evaluates the potential of existing participation formats to transform the political system into a cooperative and deliberative democracy. The aim is to develop recommendations for the integration of cooperative and deliberative elements into representative democracy, rather than to develop an alternative model. These new elements take societal demands for increased involvement into account. The normative assumption that the public should not only be involved in elections but also in the preparation of collectively binding decisions and in the assignment of trade-offs between various political options serves as the basis for the theoretical reflection. The results of this project have significant implications for future projects on two levels. On the procedural level, the participation matrix offers opportunities for combining and recombining individual procedures and procedural elements. On the substantive level, the political recommendations offer structural advise on how to realise a new participation culture through politics and administration. This can also be described as a “mainstreaming” of participation. The recommendations promote attempts at increased participation and the establishment of a “culture of participation”. This, however, is bound to certain conditions, which are also listed and explained. Ultimately, the institutional foundation of such a participation culture is localised in a serious attempt to implement mainstreaming of participation on all levels of politics and administration

Digital support of narrative writing skills for students with special educational needs. A systematic review

Die Fähigkeit, Gedanken schriftlich festzuhalten, ist für gesellschaftliche Teilhabe unabdingbar. Viele Schülerinnen und Schüler erwerben diese Kompetenz jedoch nicht in ausreichendem Maße und benötigen deswegen eine zusätzliche spezifische Förderung. Vor dem Hintergrund einer zunehmenden Bedeutung der Digitalisierung im Bildungsbereich stellt sich die Frage, welche wissenschaftlichen Erkenntnisse bezüglich digitaler Schreibinterventionen bei Schülerinnen und Schülern mit unterschiedlichen diagnostizierten Unterstützungsbedarfen existieren. Das vorliegende systematische Literatur-Review gibt einen Überblick über den gegenwärtigen internationalen Forschungsstand. Insgesamt wurden 40 Zeitschriftenartikel und 11 Dissertationen in die Beurteilung einbezogen. Es zeigt sich, dass digitale Förderung unabhängig vom Förderbedarf, vom Alter und von der Schulform dazu beitragen kann, die narrative Schreibkompetenz zu verbessern. Eine Zuordnung der genutzten digitalen Elemente anhand des SAMR-Modells (Puentedura, 2006) gibt einen Hinweis darauf, dass diese hauptsächlich die analogen Elemente ersetzen und erweitern und weniger der Umgestaltung der Aufgaben zuzuordnen sind. Trotz der Vielzahl an einschlägigen empirischen Arbeiten ist die Datenbasis im Hinblick auf hochwertige Studien allerdings noch zu gering, um verlässliche und allgemeingültige Aussagen über die Wirkungen treffen zu können. (DIPF/Orig.)The ability to capture thoughts in a written form is essential for social participation. However, many students develop this skill insufficiently and therefore require additional specific support. Digitalization in education is gaining in importance. The question therefore arises which scientific findings exist regarding digital writing interventions for students with different diagnosed educational needs. This systematic literature review provides an overview of the current state of international research. A total of 40 journal articles and 11 dissertations were included in the review. It is found that digital support is able to improve narrative writing skills regardless of diagnosed educational need, age, and school type. A categorization of the digital elements used based on the SAMR model (Puentedura, 2006) indicates that they mainly substitute and augment the analog elements and are less associated with modification and redefinition. However, despite the large amount of relevant empirical works, the data base in terms of high-quality studies is still too small to draw reliable and generalizable conclusions about the effects. (DIPF/Orig.

Microbial fuel cells: From fundamentals to applications. A review

© 2017 The Author(s) In the past 10–15 years, the microbial fuel cell (MFC) technology has captured the attention of the scientific community for the possibility of transforming organic waste directly into electricity through microbially catalyzed anodic, and microbial/enzymatic/abiotic cathodic electrochemical reactions. In this review, several aspects of the technology are considered. Firstly, a brief history of abiotic to biological fuel cells and subsequently, microbial fuel cells is presented. Secondly, the development of the concept of microbial fuel cell into a wider range of derivative technologies, called bioelectrochemical systems, is described introducing briefly microbial electrolysis cells, microbial desalination cells and microbial electrosynthesis cells. The focus is then shifted to electroactive biofilms and electron transfer mechanisms involved with solid electrodes. Carbonaceous and metallic anode materials are then introduced, followed by an explanation of the electro catalysis of the oxygen reduction reaction and its behavior in neutral media, from recent studies. Cathode catalysts based on carbonaceous, platinum-group metal and platinum-group-metal-free materials are presented, along with membrane materials with a view to future directions. Finally, microbial fuel cell practical implementation, through the utilization of energy output for practical applications, is described

Human Practice. Digital Ecologies. Our Future. : 14. Internationale Tagung Wirtschaftsinformatik (WI 2019) : Tagungsband

Erschienen bei: universi - Universitätsverlag Siegen. - ISBN: 978-3-96182-063-4Aus dem Inhalt: Track 1: Produktion & Cyber-Physische Systeme Requirements and a Meta Model for Exchanging Additive Manufacturing Capacities Service Systems, Smart Service Systems and Cyber- Physical Systems—What’s the difference? Towards a Unified Terminology Developing an Industrial IoT Platform – Trade-off between Horizontal and Vertical Approaches Machine Learning und Complex Event Processing: Effiziente Echtzeitauswertung am Beispiel Smart Factory Sensor retrofit for a coffee machine as condition monitoring and predictive maintenance use case Stakeholder-Analyse zum Einsatz IIoT-basierter Frischeinformationen in der Lebensmittelindustrie Towards a Framework for Predictive Maintenance Strategies in Mechanical Engineering - A Method-Oriented Literature Analysis Development of a matching platform for the requirement-oriented selection of cyber physical systems for SMEs Track 2: Logistic Analytics An Empirical Study of Customers’ Behavioral Intention to Use Ridepooling Services – An Extension of the Technology Acceptance Model Modeling Delay Propagation and Transmission in Railway Networks What is the impact of company specific adjustments on the acceptance and diffusion of logistic standards? Robust Route Planning in Intermodal Urban Traffic Track 3: Unternehmensmodellierung & Informationssystemgestaltung (Enterprise Modelling & Information Systems Design) Work System Modeling Method with Different Levels of Specificity and Rigor for Different Stakeholder Purposes Resolving Inconsistencies in Declarative Process Models based on Culpability Measurement Strategic Analysis in the Realm of Enterprise Modeling – On the Example of Blockchain-Based Initiatives for the Electricity Sector Zwischenbetriebliche Integration in der Möbelbranche: Konfigurationen und Einflussfaktoren Novices’ Quality Perceptions and the Acceptance of Process Modeling Grammars Entwicklung einer Definition für Social Business Objects (SBO) zur Modellierung von Unternehmensinformationen Designing a Reference Model for Digital Product Configurators Terminology for Evolving Design Artifacts Business Role-Object Specification: A Language for Behavior-aware Structural Modeling of Business Objects Generating Smart Glasses-based Information Systems with BPMN4SGA: A BPMN Extension for Smart Glasses Applications Using Blockchain in Peer-to-Peer Carsharing to Build Trust in the Sharing Economy Testing in Big Data: An Architecture Pattern for a Development Environment for Innovative, Integrated and Robust Applications Track 4: Lern- und Wissensmanagement (e-Learning and Knowledge Management) eGovernment Competences revisited – A Literature Review on necessary Competences in a Digitalized Public Sector Say Hello to Your New Automated Tutor – A Structured Literature Review on Pedagogical Conversational Agents Teaching the Digital Transformation of Business Processes: Design of a Simulation Game for Information Systems Education Conceptualizing Immersion for Individual Learning in Virtual Reality Designing a Flipped Classroom Course – a Process Model The Influence of Risk-Taking on Knowledge Exchange and Combination Gamified Feedback durch Avatare im Mobile Learning Alexa, Can You Help Me Solve That Problem? - Understanding the Value of Smart Personal Assistants as Tutors for Complex Problem Tasks Track 5: Data Science & Business Analytics Matching with Bundle Preferences: Tradeoff between Fairness and Truthfulness Applied image recognition: guidelines for using deep learning models in practice Yield Prognosis for the Agrarian Management of Vineyards using Deep Learning for Object Counting Reading Between the Lines of Qualitative Data – How to Detect Hidden Structure Based on Codes Online Auctions with Dual-Threshold Algorithms: An Experimental Study and Practical Evaluation Design Features of Non-Financial Reward Programs for Online Reviews: Evaluation based on Google Maps Data Topic Embeddings – A New Approach to Classify Very Short Documents Based on Predefined Topics Leveraging Unstructured Image Data for Product Quality Improvement Decision Support for Real Estate Investors: Improving Real Estate Valuation with 3D City Models and Points of Interest Knowledge Discovery from CVs: A Topic Modeling Procedure Online Product Descriptions – Boost for your Sales? Entscheidungsunterstützung durch historienbasierte Dienstreihenfolgeplanung mit Pattern A Semi-Automated Approach for Generating Online Review Templates Machine Learning goes Measure Management: Leveraging Anomaly Detection and Parts Search to Improve Product-Cost Optimization Bedeutung von Predictive Analytics für den theoretischen Erkenntnisgewinn in der IS-Forschung Track 6: Digitale Transformation und Dienstleistungen Heuristic Theorizing in Software Development: Deriving Design Principles for Smart Glasses-based Systems Mirroring E-service for Brick and Mortar Retail: An Assessment and Survey Taxonomy of Digital Platforms: A Platform Architecture Perspective Value of Star Players in the Digital Age Local Shopping Platforms – Harnessing Locational Advantages for the Digital Transformation of Local Retail Outlets: A Content Analysis A Socio-Technical Approach to Manage Analytics-as-a-Service – Results of an Action Design Research Project Characterizing Approaches to Digital Transformation: Development of a Taxonomy of Digital Units Expectations vs. Reality – Benefits of Smart Services in the Field of Tension between Industry and Science Innovation Networks and Digital Innovation: How Organizations Use Innovation Networks in a Digitized Environment Characterising Social Reading Platforms— A Taxonomy-Based Approach to Structure the Field Less Complex than Expected – What Really Drives IT Consulting Value Modularity Canvas – A Framework for Visualizing Potentials of Service Modularity Towards a Conceptualization of Capabilities for Innovating Business Models in the Industrial Internet of Things A Taxonomy of Barriers to Digital Transformation Ambidexterity in Service Innovation Research: A Systematic Literature Review Design and success factors of an online solution for cross-pillar pension information Track 7: IT-Management und -Strategie A Frugal Support Structure for New Software Implementations in SMEs How to Structure a Company-wide Adoption of Big Data Analytics The Changing Roles of Innovation Actors and Organizational Antecedents in the Digital Age Bewertung des Kundennutzens von Chatbots für den Einsatz im Servicedesk Understanding the Benefits of Agile Software Development in Regulated Environments Are Employees Following the Rules? On the Effectiveness of IT Consumerization Policies Agile and Attached: The Impact of Agile Practices on Agile Team Members’ Affective Organisational Commitment The Complexity Trap – Limits of IT Flexibility for Supporting Organizational Agility in Decentralized Organizations Platform Openness: A Systematic Literature Review and Avenues for Future Research Competence, Fashion and the Case of Blockchain The Digital Platform Otto.de: A Case Study of Growth, Complexity, and Generativity Track 8: eHealth & alternde Gesellschaft Security and Privacy of Personal Health Records in Cloud Computing Environments – An Experimental Exploration of the Impact of Storage Solutions and Data Breaches Patientenintegration durch Pfadsysteme Digitalisierung in der Stressprävention – eine qualitative Interviewstudie zu Nutzenpotenzialen User Dynamics in Mental Health Forums – A Sentiment Analysis Perspective Intent and the Use of Wearables in the Workplace – A Model Development Understanding Patient Pathways in the Context of Integrated Health Care Services - Implications from a Scoping Review Understanding the Habitual Use of Wearable Activity Trackers On the Fit in Fitness Apps: Studying the Interaction of Motivational Affordances and Users’ Goal Orientations in Affecting the Benefits Gained Gamification in Health Behavior Change Support Systems - A Synthesis of Unintended Side Effects Investigating the Influence of Information Incongruity on Trust-Relations within Trilateral Healthcare Settings Track 9: Krisen- und Kontinuitätsmanagement Potentiale von IKT beim Ausfall kritischer Infrastrukturen: Erwartungen, Informationsgewinnung und Mediennutzung der Zivilbevölkerung in Deutschland Fake News Perception in Germany: A Representative Study of People’s Attitudes and Approaches to Counteract Disinformation Analyzing the Potential of Graphical Building Information for Fire Emergency Responses: Findings from a Controlled Experiment Track 10: Human-Computer Interaction Towards a Taxonomy of Platforms for Conversational Agent Design Measuring Service Encounter Satisfaction with Customer Service Chatbots using Sentiment Analysis Self-Tracking and Gamification: Analyzing the Interplay of Motivations, Usage and Motivation Fulfillment Erfolgsfaktoren von Augmented-Reality-Applikationen: Analyse von Nutzerrezensionen mit dem Review-Mining-Verfahren Designing Dynamic Decision Support for Electronic Requirements Negotiations Who is Stressed by Using ICTs? A Qualitative Comparison Analysis with the Big Five Personality Traits to Understand Technostress Walking the Middle Path: How Medium Trade-Off Exposure Leads to Higher Consumer Satisfaction in Recommender Agents Theory-Based Affordances of Utilitarian, Hedonic and Dual-Purposed Technologies: A Literature Review Eliciting Customer Preferences for Shopping Companion Apps: A Service Quality Approach The Role of Early User Participation in Discovering Software – A Case Study from the Context of Smart Glasses The Fluidity of the Self-Concept as a Framework to Explain the Motivation to Play Video Games Heart over Heels? An Empirical Analysis of the Relationship between Emotions and Review Helpfulness for Experience and Credence Goods Track 11: Information Security and Information Privacy Unfolding Concerns about Augmented Reality Technologies: A Qualitative Analysis of User Perceptions To (Psychologically) Own Data is to Protect Data: How Psychological Ownership Determines Protective Behavior in a Work and Private Context Understanding Data Protection Regulations from a Data Management Perspective: A Capability-Based Approach to EU-GDPR On the Difficulties of Incentivizing Online Privacy through Transparency: A Qualitative Survey of the German Health Insurance Market What is Your Selfie Worth? A Field Study on Individuals’ Valuation of Personal Data Justification of Mass Surveillance: A Quantitative Study An Exploratory Study of Risk Perception for Data Disclosure to a Network of Firms Track 12: Umweltinformatik und nachhaltiges Wirtschaften Kommunikationsfäden im Nadelöhr – Fachliche Prozessmodellierung der Nachhaltigkeitskommunikation am Kapitalmarkt Potentiale und Herausforderungen der Materialflusskostenrechnung Computing Incentives for User-Based Relocation in Carsharing Sustainability’s Coming Home: Preliminary Design Principles for the Sustainable Smart District Substitution of hazardous chemical substances using Deep Learning and t-SNE A Hierarchy of DSMLs in Support of Product Life-Cycle Assessment A Survey of Smart Energy Services for Private Households Door-to-Door Mobility Integrators as Keystone Organizations of Smart Ecosystems: Resources and Value Co-Creation – A Literature Review Ein Entscheidungsunterstützungssystem zur ökonomischen Bewertung von Mieterstrom auf Basis der Clusteranalyse Discovering Blockchain for Sustainable Product-Service Systems to enhance the Circular Economy Digitale Rückverfolgbarkeit von Lebensmitteln: Eine verbraucherinformatische Studie Umweltbewusstsein durch audiovisuelles Content Marketing? Eine experimentelle Untersuchung zur Konsumentenbewertung nachhaltiger Smartphones Towards Predictive Energy Management in Information Systems: A Research Proposal A Web Browser-Based Application for Processing and Analyzing Material Flow Models using the MFCA Methodology Track 13: Digital Work - Social, mobile, smart On Conversational Agents in Information Systems Research: Analyzing the Past to Guide Future Work The Potential of Augmented Reality for Improving Occupational First Aid Prevent a Vicious Circle! The Role of Organizational IT-Capability in Attracting IT-affine Applicants Good, Bad, or Both? Conceptualization and Measurement of Ambivalent User Attitudes Towards AI A Case Study on Cross-Hierarchical Communication in Digital Work Environments ‘Show Me Your People Skills’ - Employing CEO Branding for Corporate Reputation Management in Social Media A Multiorganisational Study of the Drivers and Barriers of Enterprise Collaboration Systems-Enabled Change The More the Merrier? The Effect of Size of Core Team Subgroups on Success of Open Source Projects The Impact of Anthropomorphic and Functional Chatbot Design Features in Enterprise Collaboration Systems on User Acceptance Digital Feedback for Digital Work? Affordances and Constraints of a Feedback App at InsurCorp The Effect of Marker-less Augmented Reality on Task and Learning Performance Antecedents for Cyberloafing – A Literature Review Internal Crowd Work as a Source of Empowerment - An Empirical Analysis of the Perception of Employees in a Crowdtesting Project Track 14: Geschäftsmodelle und digitales Unternehmertum Dividing the ICO Jungle: Extracting and Evaluating Design Archetypes Capturing Value from Data: Exploring Factors Influencing Revenue Model Design for Data-Driven Services Understanding the Role of Data for Innovating Business Models: A System Dynamics Perspective Business Model Innovation and Stakeholder: Exploring Mechanisms and Outcomes of Value Creation and Destruction Business Models for Internet of Things Platforms: Empirical Development of a Taxonomy and Archetypes Revitalizing established Industrial Companies: State of the Art and Success Principles of Digital Corporate Incubators When 1+1 is Greater than 2: Concurrence of Additional Digital and Established Business Models within Companies Special Track 1: Student Track Investigating Personalized Price Discrimination of Textile-, Electronics- and General Stores in German Online Retail From Facets to a Universal Definition – An Analysis of IoT Usage in Retail Is the Technostress Creators Inventory Still an Up-To-Date Measurement Instrument? Results of a Large-Scale Interview Study Application of Media Synchronicity Theory to Creative Tasks in Virtual Teams Using the Example of Design Thinking TrustyTweet: An Indicator-based Browser-Plugin to Assist Users in Dealing with Fake News on Twitter Application of Process Mining Techniques to Support Maintenance-Related Objectives How Voice Can Change Customer Satisfaction: A Comparative Analysis between E-Commerce and Voice Commerce Business Process Compliance and Blockchain: How Does the Ethereum Blockchain Address Challenges of Business Process Compliance? Improving Business Model Configuration through a Question-based Approach The Influence of Situational Factors and Gamification on Intrinsic Motivation and Learning Evaluation von ITSM-Tools für Integration und Management von Cloud-Diensten am Beispiel von ServiceNow How Software Promotes the Integration of Sustainability in Business Process Management Criteria Catalog for Industrial IoT Platforms from the Perspective of the Machine Tool Industry Special Track 3: Demos & Prototyping Privacy-friendly User Location Tracking with Smart Devices: The BeaT Prototype Application-oriented robotics in nursing homes Augmented Reality for Set-up Processe Mixed Reality for supporting Remote-Meetings Gamification zur Motivationssteigerung von Werkern bei der Betriebsdatenerfassung Automatically Extracting and Analyzing Customer Needs from Twitter: A “Needmining” Prototype GaNEsHA: Opportunities for Sustainable Transportation in Smart Cities TUCANA: A platform for using local processing power of edge devices for building data-driven services Demonstrator zur Beschreibung und Visualisierung einer kritischen Infrastruktur Entwicklung einer alltagsnahen persuasiven App zur Bewegungsmotivation für ältere Nutzerinnen und Nutzer A browser-based modeling tool for studying the learning of conceptual modeling based on a multi-modal data collection approach Exergames & Dementia: An interactive System for People with Dementia and their Care-Network Workshops Workshop Ethics and Morality in Business Informatics (Workshop Ethik und Moral in der Wirtschaftsinformatik – EMoWI’19) Model-Based Compliance in Information Systems - Foundations, Case Description and Data Set of the MobIS-Challenge for Students and Doctoral Candidates Report of the Workshop on Concepts and Methods of Identifying Digital Potentials in Information Management Control of Systemic Risks in Global Networks - A Grand Challenge to Information Systems Research Die Mitarbeiter von morgen - Kompetenzen künftiger Mitarbeiter im Bereich Business Analytics Digitaler Konsum: Herausforderungen und Chancen der Verbraucherinformati

Microbe-host interplay in atopic dermatitis and psoriasis

Despite recent advances in understanding microbial diversity in skin homeostasis, the relevance of microbial dysbiosis in inflammatory disease is poorly understood. Here we perform a comparative analysis of skin microbial communities coupled to global patterns of cutaneous gene expression in patients with atopic dermatitis or psoriasis. The skin microbiota is analysed by 16S amplicon or whole genome sequencing and the skin transcriptome by microarrays, followed by integration of the data layers. We find that atopic dermatitis and psoriasis can be classified by distinct microbes, which differ from healthy volunteers microbiome composition. Atopic dermatitis is dominated by a single microbe (Staphylococcus aureus), and associated with a disease relevant host transcriptomic signature enriched for skin barrier function, tryptophan metabolism and immune activation. In contrast, psoriasis is characterized by co-occurring communities of microbes with weak associations with disease related gene expression. Our work provides a basis for biomarker discovery and targeted therapies in skin dysbiosis.Peer reviewe