292 research outputs found

    Robinson-Patman Act and the Accountant

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    Three-Dimensional Thermoluminescence Spectra and Their Application in the Study of Some Sedimentary Quartz

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    The intensity of thermoluminescence emission is a function of both temperature and photon energy (or wavelength) and therefore lends itself to a three-dimensional (3-D) display, either in the form of an isometric plot or a contour diagram. The technique of 3-D thermoluminescence spectrometry is briefly reviewed and the advantages and applications are illustrated by reference to the spectral properties of samples of Australian sedimentary quartz drawn from the context of thermoluminescence dating. In this context, the temperature of emission, the photon energy and the ease with which the emission is bleachable by sunlight are of significance. It is suggested that, in one of the samples, the energy of the photon emitted from one of the luminescence centres depends on the temperature of emission

    Paediatric Intensive Care follow-up provision in the UK and Republic of Ireland

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    ObjectiveTo examine the characteristic, content and role of Paediatric Intensive Care Units (PICUs) in the provision of follow-up for children and their families’ post-intensive care discharge in the United Kingdom and Republic of Ireland.DesignDescriptive self-reported, web-based survey design. ‘In-hospital PICU follow-up’ was defined as follow-up delivered by the PICU team following PICU discharge but before hospital discharge and ‘post-discharge PICU follow-up’ was defined as follow-up delivered by the PICU team following hospital discharge. SettingSurvey administered to all 28 PICUs in the United Kingdom and Republic of Ireland.ParticipantsPediatric Intensive Care medical directors or delegated individual.Measurements and main resultsData were collected between September 2017-January 2018 with a response rate of 79% (n=22/28). Twelve units provided either in-hospital and/or post-discharge PICU follow-up. Ten (45%) PICUs reported providing in-hospital follow-up, with half (n=5) using an eligibility criteria for in-hospital follow-up which related to disease groups. The most frequently reported form of in-hospital PICU follow-up consisted of face-to-face patient consultation (n=8) by a PICU doctor (n=5) and/or nurse (n=4). The time at which initial contact was made was usually not pre-determined (n=4) and the care needs assessed included: tracheostomy care (n=4); respiratory care (n=4); and sedative medication weaning plan (n=5). Four PICUs reported to provide post-discharge follow-up. This involved telephone (n=2), follow-up clinic consultations (n=1) or home visits (n=1), provided predominantly by PICU doctors (n=2), with their activity directed by patient needs (n=3).ConclusionsDespite increasing evidence to suggest PICU survivors and their families experience negative sequalae post-PICU discharge, less than half of PICUs surveyed provide in-hospital follow-up and only a minority provide post-discharge follow-up. There is variation in the delivery, content and format of in-hospital and post-discharge PICU follow-up in the United Kingdom and Republic of Ireland

    The impact of population-based faecal occult blood test screening on colorectal cancer mortality:a matched cohort study

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    BACKGROUND: Randomised trials show reduced colorectal cancer (CRC) mortality with faecal occult blood testing (FOBT). This outcome is now examined in a routine, population-based, screening programme. METHODS: Three biennial rounds of the UK CRC screening pilot were completed in Scotland (2000–2007) before the roll out of a national programme. All residents (50–69 years) in the three pilot Health Boards were invited for screening. They received a FOBT test by post to complete at home and return for analysis. Positive tests were followed up with colonoscopy. Controls, selected from non-pilot Health Boards, were matched by age, gender, and deprivation and assigned the invitation date of matched invitee. Follow-up was from invitation date to 31 December 2009 or date of death if earlier. RESULTS: There were 379 655 people in each group (median age 55.6 years, 51.6% male). Participation was 60.6%. There were 961 (0.25%) CRC deaths in invitees, 1056 (0.28%) in controls, rate ratio (RR) 0.90 (95% confidence interval (CI) 0.83–0.99) overall and 0.73 (95% CI 0.65–0.82) for participants. Non-participants had increased CRC mortality compared with controls, RR 1.21 (95% CI 1.06–1.38). CONCLUSION: There was a 10% relative reduction in CRC mortality in a routine screening programme, rising to 27% in participants

    Peri‐operative cardiac arrest in children as reported to the 7th National Audit Project of the Royal College of Anaesthetists

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    The 7th National Audit Project of the Royal College of Anaesthetists studied peri‐operative cardiac arrest. An activity survey estimated UK paediatric anaesthesia annual caseload as 390,000 cases, 14% of the UK total. Paediatric peri‐operative cardiac arrests accounted for 104 (12%) reports giving an incidence of 3 in 10,000 anaesthetics (95%CI 2.2–3.3 per 10,000). The incidence of peri‐operative cardiac arrest was highest in neonates (27, 26%), infants (36, 35%) and children with congenital heart disease (44, 42%) and most reports were from tertiary centres (88, 85%). Frequent precipitants of cardiac arrest in non‐cardiac surgery included: severe hypoxaemia (20, 22%); bradycardia (10, 11%); and major haemorrhage (9, 8%). Cardiac tamponade and isolated severe hypotension featured prominently as causes of cardiac arrest in children undergoing cardiac surgery or cardiological procedures. Themes identified at review included: inappropriate choices and doses of anaesthetic drugs for intravenous induction; bradycardias associated with high concentrations of volatile anaesthetic agent or airway manipulation; use of atropine in the place of adrenaline; and inadequate monitoring. Overall quality of care was judged by the panel to be good in 64 (62%) cases, which compares favourably with adults (371, 52%). The study provides insight into paediatric anaesthetic practice, complications and peri‐operative cardiac arrest

    The 7th National Audit Project (NAP7) baseline survey of individual anaesthetists: preparedness for and experiences of peri-operative cardiac arrest

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    The Royal College of Anaesthetists' 7th National Audit Project baseline survey assessed knowledge, attitudes, practices and experiences of peri-operative cardiac arrests among UK anaesthetists and Anaesthesia Associates. We received 10,746 responses, representing a 71% response rate. In-date training in adult and paediatric advanced life support was reported by 9646 (90%) and 7125 (66%) anaesthetists, respectively. There were 8994 (84%) respondents who were confident in leading a peri-operative cardiac arrest, with males more confident than females, but only 5985 (56%) were confident in leading a debrief and 7340 (68%) communicating with next of kin. In the previous two years, 4806 (46%) respondents had managed at least one peri-operative cardiac arrest, of which 321 (7%) and 189 (4%) of these events involved a child or an obstetric patient, respectively. Respondents estimated the most common causes of peri-operative cardiac arrest to be hypovolaemia, hypoxaemia and cardiac ischaemia, with haemorrhage coming fifth. However, the most common reported causes for the most recently attended peri-operative cardiac arrest were haemorrhage; (927, 20%); anaphylaxis (474, 10%); and cardiac ischaemia (397, 9%). Operating lists or shifts were paused or stopped after 1330 (39%) cardiac arrests and 1693 (38%) respondents attended a debrief, with ‘hot’ debriefs most common. Informal wellbeing support was relatively common (2458, 56%) and formal support was uncommon (472, 11%). An impact on future care delivery was reported by 196 (4%) anaesthetists, most commonly a negative psychological impact. Management of a peri-operative cardiac arrest during their career was reported by 8654 (85%) respondents. The overall impact on professional life was more often judged positive (2630, 30%) than negative (1961, 23%), but impact on personal life was more often negative
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