Spirit Mediumship in Brazil: The Controversy about Semi-Conscious Mediums

This article focuses on spirit mediumship in Brazil. The term mediumship refers to the communication between humans the spirit world which is the core of Spiritism. In anthropological literature it is often categorised as altered states of consciousness, however, people experiencing it reject these categorizations. This article presents excerpts from interviews with Brazilian spiritists in order to illustrate the different ways people explain mediumship to an outsider, an anthropologist from Europe. The article then discusses their interpretation within the wider academic discourse surrounding this kind of experience. The intention is that Brazilian Spiritism and the wider discourse surrounding mediumship will serve as a case study to present the complexity of this form of religious experience

Spirit Possession in Brazil: The Perception of the (possessed) Body

Spirit possession is the core religious practice in most Afro- American religions. It is usually described as "mounting"; the spirit "rides" the body of the devotee as a horseman rides a horse. The description projects the image that a spirit takes control over the body of the medium and "uses" the human medium; the body of the person is passive and submissive, while the spirit is active and dominant. However, this view does not reflect the highly elaborate discourse about spirit possession in Brazil. The article is based on fieldwork among communities of Afro-Brazilian and Spiritist traditions in São Paulo, Brazil. Based on subjective narratives about bodily experience and the academic debate about body and mind, the article contributes to a wider understanding of the possession experience

Mediumship as Ordinary Experience: An anthropological discussion of ordinary vs non-ordinary – What is the difference?

Using the study of mediumship (spirit possession) as a case study the chapter discusses the methodological differences between labelling an experience as ordinary or non-ordinary. In addition to challenging academic labelling the chapter puts forward the argument to opening the study of religious and spiritual experience in light of Peggy Morgan’s work. The first section looks back at the beginning of the academic study of experience and highlights the contribution of the early Oxford anthropologist R.R. Marrett. Comparing his work with Rudolf Otto’s theological approach it argues against limiting the study to ‘religious experience’. The second section presents the case of seeing mediumship as ordinary experience. Referring to Irving Hallowell’s concept of ‘other than human persons’ and Tim Ingold’s critique of agency it argues that an approach to experience as ordinary can further our understanding

Defense Mechanisms of Hepatocytes Against Burkholderia pseudomallei

The Gram-negative facultative intracellular rod Burkholderia pseudomallei causes melioidosis, an infectious disease with a wide range of clinical presentations. Among the observed visceral abscesses, the liver is commonly affected. However, neither this organotropism of B. pseudomallei nor local hepatic defense mechanisms have been thoroughly investigated so far. Own previous studies using electron microscopy of the murine liver after systemic infection of mice indicated that hepatocytes might be capable of killing B. pseudomallei. Therefore, the aim of this study was to further elucidate the interaction of B. pseudomallei with these cells and to analyze the role of hepatocytes in anti-B. pseudomallei host defense. In vitro studies using the human hepatocyte cell line HepG2 revealed that B. pseudomallei can invade these cells. Subsequently, B. pseudomallei is able to escape from the vacuole, to replicate within the cytosol of HepG2 cells involving its type 3 and type 6 secretion systems, and to induce actin tail formation. Furthermore, stimulation of HepG2 cells showed that IFNγ can restrict growth of B. pseudomallei in the early and late phase of infection whereas the combination of IFNγ, IL-1β, and TNFα is required for the maximal antibacterial activity. This anti-B. pseudomallei defense of HepG2 cells did not seem to be mediated by inducible nitric oxide synthase-derived nitric oxide or NADPH oxidase-derived superoxide. In summary, this is the first study describing B. pseudomallei intracellular life cycle characteristics in hepatocytes and showing that IFNγ-mediated, but nitric oxide- and reactive oxygen species-independent, effector mechanisms are important in anti-B. pseudomallei host defense of hepatocytes

Communication and signal exchange in the Rhizobium bradyrhizobium legume system

A new comprehensive communication concept in the Rhizobium/Bradyrhizobium legume symbiosis was developed. It includes a root zone specific flavonoid exudation, the differential activity of phenylpropane/acetate pathway derivatives on chemotaxis, nod-gene inducing activity and phytoalexin resistance induction on the microsymbiont side (Bradyrhizobium). Nod factor production from the microsymbiont affects the host plant in root hair curling and meristem induction. Phytoalexin production in the host plant is also an early response, however repressed to a low level after a few hours. Another strategy of the microsymbiont to overcome phytoalexin effects is degradation of phytoalexins in Rhizobium leguminosarum bv. vicieae. Competitiveness within the same infection group of the microsymbiont was studied with gus-gene fusion, using the blue coloured nodules to easily discriminate marked strains from unmarked competitors. New exopolysaccharide (EPS) mutants of Bradyrhizobium japonicum were reconstructed homologous with a DNA region to exoB gene of Rhizobium meliloti. Their clearly reduced competitiveness of nodulation, demonstrates that exopolysaccharides of Bradyrhizohium japonicum also have an important function during the early stages of this symbiotic interaction

Alister Hardy: a naturalist of the spiritual realm

Alister Hardy was one of the pioneers of the scientific study of spiritual experiences (SE), however his work and insights have not received the attention they deserve. This paper, based on in-depth analysis of Hardy`s own writings, presents his main methodological and epistemological con-tributions for advancing the investigation of SE. Hardy’s main epistemological guidelines were: the transcendent as the core of spirituality and SE as a major source of R/S beliefs; non-dogmatic approach, acknowledging that Darwinian evolution does not imply materialism and mind is not reducible to matter; call for studies of psychic experiences and considering an expanded natu-ralism, including the “para-physical” that could lead to a perennial philosophy and a natural theology. His methods focused on a phenomenological classification and the development of a natural history of SE based on studies with proper ecological validity on the experimental and the experiential, mixing large surveys of the general population with in-depth qualitative studies of the most prominent cases. In addition, it would be worth investigating developments of SE throughout a person’s life. Bringing back Hardy`s contributions will foster a better understanding of the history of the scientific study of SE and provide key insights for moving it forward

Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces

Background: Early microbial colonization of the gut reduces the incidence of infectious, inflammatory and autoimmune diseases. Recent population studies reveal that childhood hygiene is a significant risk factor for development of inflammatory bowel disease, thereby reinforcing the hygiene hypothesis and the potential importance of microbial colonization during early life. The extent to which early-life environment impacts on microbial diversity of the adult gut and subsequent immune processes has not been comprehensively investigated thus far. We addressed this important question using the pig as a model to evaluate the impact of early-life environment on microbe/host gut interactions during development. Results: Genetically-related piglets were housed in either indoor or outdoor environments or in experimental isolators. Analysis of over 3,000 16S rRNA sequences revealed major differences in mucosa-adherent microbial diversity in the ileum of adult pigs attributable to differences in early-life environment. Pigs housed in a natural outdoor environment showed a dominance of Firmicutes, in particular Lactobacillus, whereas animals housed in a hygienic indoor environment had reduced Lactobacillus and higher numbers of potentially pathogenic phylotypes. Our analysis revealed a strong negative correlation between the abundance of Firmicutes and pathogenic bacterial populations in the gut. These differences were exaggerated in animals housed in experimental isolators. Affymetrix microarray technology and Real-time Polymerase Chain Reaction revealed significant gut-specific gene responses also related to early-life environment. Significantly, indoor-housed pigs displayed increased expression of Type 1 interferon genes, Major Histocompatibility Complex class I and several chemokines. Gene Ontology and pathway analysis further confirmed these results. Conclusion: Early-life environment significantly affects both microbial composition of the adult gut and mucosal innate immune function. We observed that a microbiota dominated by lactobacilli may function to maintain mucosal immune homeostasis and limit pathogen colonization

Structural Correlates of Taste and Smell Loss in Encephalitis Disseminata

BACKGROUND: Olfactory dysfunction in MS patients is reported in the literature. MRI of the olfactory bulb (OB) is discussed as a promising new testing method for measuring olfactory function (OF). Aim of this study was to explore reasons for and optimize the detection of olfactory dysfunction in MS patients with MRI. MATERIALS AND METHODS: OB and olfactory brain volume was assessed within 34 MS patients by manual segmentation. Olfactory function was tested using the Threshold-Discrimination-Identification-Test (TDI), gustatory function was tested using Taste Strips (TST). RESULTS: 41% of the MS patients displayed olfactory dysfunction (8% of the control group), 16% displayed gustatory dysfunction (5% of the control group). There was a correlation between the OB volume and the number and volume of MS lesions in the olfactory brain. Olfactory brain volume correlated with the volume of lesions in the olfactory brain and the EDSS score. The TST score correlated with the number and volume of lesions in the olfactory brain. CONCLUSION: The correlation between a higher number and volume of MS lesions with a decreased OB and olfactory brain volume could help to explain olfactory dysfunction