Delayed-choice quantum eraser for the undergraduate laboratory

In a delayed-choice quantum eraser, interference fringes are obtained by erasing which-way information after the interfering particle has already been irreversibly detected. Following an introductory review of delayed-choice experiments and quantum erasure, we describe the experimental realization of an optical delayed-choice quantum eraser, suitable for advanced undergraduates, based on polarization-entangled pairs of single photons. In our experiment, the delay of the erasure is implemented using two different setups. The first setup employs an arrangement of mirrors to increase the optical path length of the photons carrying which-way information. In the second setup, we use fiber-optic cables to elongate the path of these photons after their passage through the polarization analyzer but prior to their arrival at the detector. We compare our results to data obtained in the absence of a delay and find excellent agreement. This shows that the timing of the erasure is irrelevant, as also predicted by quantum mechanics. The experiment can serve as a valuable pedagogical tool for conveying the fundamentals of quantum mechanics.Comment: 13 pages, 5 figures, identical to published versio

Observation of the quantum paradox of separation of a single photon from one of its properties

We report an experimental realization of the quantum paradox of the separation of a single photon from one of its properties (the so-called "quantum Cheshire cat"). We use a modified Sagnac interferometer with displaced paths to produce appropriately pre- and postselected states of heralded single photons. Weak measurements of photon presence and circular polarization are performed in each arm of the interferometer by introducing weak absorbers and small polarization rotations and analyzing changes in the postselected signal. The absorber is found to have an appreciable effect only in one arm of the interferometer, while the polarization rotation significantly affects the signal only when performed in the other arm. We carry out both sequential and simultaneous weak measurements and find good agreement between measured and predicted weak values. In the language of Aharonov et al. and in the sense of the ensemble averages described by weak values, the experiment establishes the separation of a particle from one its properties during the passage through the interferometer.Comment: 9 pages, 4 figures, identical to published versio

Laparoscopic Morcellation of Didelphic Uterus With Cervical and Renal Aplasia

Laparoscopic morcellation of the obstructed hemiuterus may be the preferred treatment of this congenital anomaly following failure of a surgical cervical fistula

Observation of the quantum paradox of separation of a single photon from one of its properties

We report an experimental realization of the quantum paradox of the separation of a single photon from one of its properties (the so-called quantum Cheshire cat ). We use a modified Sagnac interferometer with displaced paths to produce appropriately pre- and postselected states of heralded single photons. Weak measurements of photon presence and circular polarization are performed in each arm of the interferometer by introducing weak absorbers and small polarization rotations and analyzing changes in the postselected signal. The absorber is found to have an appreciable effect only in one arm of the interferometer, while the polarization rotation significantly affects the signal only when performed in the other arm. We carry out both sequential and simultaneous weak measurements and find good agreement between measured and predicted weak values. In the language of Aharonov et al. and in the sense of the ensemble averages described by weak values, the experiment establishes the separation of a particle from one its properties during the passage through the interferometer

Delayed-choice quantum eraser for the undergraduate laboratory

In a delayed-choice quantum eraser, interference fringes are obtained by erasing which-way information after the interfering particle has already been irreversibly detected. Following an introductory review of delayed-choice experiments and quantum erasure, we describe the experimental realization of an optical delayed-choice quantum eraser, suitable for advanced undergraduates, based on polarization-entangled pairs of single photons. In our experiment, the delay of the erasure is implemented using two different setups. The first setup employs an arrangement of mirrors to increase the optical path length of the photons carrying which-way information. In the second setup, we use fiber-optic cables to elongate the path of these photons after their passage through the polarization analyzer but prior to their arrival at the detector. We compare our results to data obtained in the absence of a delay and find excellent agreement. This shows that the timing of the erasure is irrelevant, as also predicted by quantum mechanics. The experiment can serve as a valuable pedagogical tool for conveying the fundamentals of quantum mechanics

Delocalization of ultracold atoms in a disordered potential due to light scattering

We numerically study the expansion dynamics of ultracold atoms in a one-dimensional disordered potential in the presence of a weak position measurement of the atoms. We specifically consider this position measurement to be realized by a combination of an external laser and a periodic array of optical microcavities along a waveguide. The position information is acquired through the scattering of a near-resonant laser photon into a specific eigenmode of one of the cavities. The time evolution of the atomic density in the presence of this light scattering mechanism is described within a Lindblad master equation approach, which is numerically implemented using the Monte Carlo wave function technique. We find that an arbitrarily weak rate of photon emission leads to a breakdown of Anderson localization of the atoms.Comment: 7 pages, 8 figure

Application of RNA-Seq transcriptome analysis: CD151 is an Invasion/Migration target in all stages of epithelial ovarian cancer

<p>Abstract</p> <p>Background</p> <p>RNA-Seq allows a theoretically unbiased analysis of both genome-wide transcription levels and mutation status of a tumor. Using this technique we sought to identify novel candidate therapeutic targets expressed in epithelial ovarian cancer (EOC).</p> <p>Methods</p> <p>Specifically, we sought candidate invasion/migration targets based on expression levels across all tumors, novelty of expression in EOC, and known function. RNA-Seq analysis revealed the high expression of CD151, a transmembrane protein, across all stages of EOC. Expression was confirmed at both the mRNA and protein levels using RT-PCR and immunohistochemical staining, respectively.</p> <p>Results</p> <p>In both EOC tumors and normal ovarian surface epithelial cells we demonstrated CD151 to be localized to the membrane and cell-cell junctions in patient-derived and established EOC cell lines. We next evaluated its role in EOC dissemination using two ovarian cancer-derived cell lines with differential levels of CD151 expression. Targeted antibody-mediated and siRNA inhibition or loss of CD151 in SKOV3 and OVCAR5 cell lines effectively inhibited their migration and invasion.</p> <p>Conclusion</p> <p>Taken together, these findings provide the first proof-of-principle demonstration for a next generation sequencing approach to identifying candidate therapeutic targets and reveal CD151 to play a role in EOC dissemination.</p