Order from Noise: Kai Ginkel über die sozialen Bedingungen der Möglichkeit von Klang

Kai Ginkel: Noise – Klang zwischen Musik und Lärm: Zu einer Praxeologie des Auditiven. Bielefeld: transcript Verlag 2017. 978-3-8376-3928-

Frames of Fraud: A Qualitative Analysis of the Structure and Process of Victimization on the Internet

Abstract In this paper, the structures and processes of Internet fraud are analyzed. By applyin

Automated Mobility and Inclusion as Educational Topics for Children and Juveniles and as Tasks and Responsibilities of Mobility Planning: Work-Report on the Project AM4Kids

Automated mobility (AM) involves the increased use of digital information and communication technologies in all areas of traffic and mobility, particularly in the vehicle and mobility sector, in the infrastructure, transportation and the management of mobility-related processes (pre-, on- and post-trip). To ensure that the potentials of AM, like higher efficiency and improving accessibility, meet the demands and mobility patterns of different types of people, especially vulnerable ones like kids and people with disabilities, it is essential to make children and young adults aware of this complex and diverse topic already today. Therefore, planning and development activities in the mobility sector should involve this future generation and consider their ideas and concerns. Planning and development activities should be considered from a holistic and inclusive perspective, considering a wide variety of traffic participant groups. In this context, the Austrian project AM4Kids 1 creates a direct interface between children and young adults and mobility planning. The scientists and planners take the role of facilitators of knowledge and accompany an inter and transdisciplinary, multi-level exchange between disciplines, such as transport planning, social science, mobility research, and actors from the inclusion sector. In the project, age-appropriate and gender-sensitive workshops, input lectures, and educational materials were developed and implemented by the interdisciplinary consortium of sociologists, transportation planners, landscape architects, civil engineers, software developers, and legal experts for the needs of people with disabilities. This paper presents the methods applied in the corresponding project phases. Furthermore, a reflection on the achieved results and experiences from the activities in project phases 1 and 2 is provided

Application of the Persona Concept to Convey Socially Sustainable and Responsible Transport System Planning to Children and Juveniles Considering Autonomous Vehicles: Work Report on the Project AM4Kids – Future Workshop

The automation in the transportation and mobility sector, particularly the use of autonomous systems in public transportation, presents novel challenges for various user groups despite offering numerous positive aspects. Autonomous vehicles, particularly in the domains of micro-public transportation and car sharing, have the potential to serve as a flexible mobility solution for individuals without a driver's license or those who are physically or mentally incapable of operating a vehicle. To ensure equitable access to this potential of independent and flexible mobility for all individuals, the design of autonomous transportation modes must be inclusive. The Austrian“AM4Kids” project (August 2020 to October 2023) imparts knowledge on mobility and transport system planning to children and juveniles in the context of the progressive automation of transportation and mobility modes, focusing on the principles of inclusive mobility offerings. Children and juveniles have attended several workshops on mobility and inclusion for over three years. In the final stage of the workshop series, the children and juveniles develop their visions and ideas for automated mobility, discussing the opportunities, risks, and consequences for themselves and other groups. One way to better understand and visualise the wide range of everyday lives of people with disabilities, their mobility patterns, and mobility options is to use the persona concept. This method aims at packaging real users’ motivations, needs, wishes and ambitions in a model to better integrate future research and technology development of automated mobility with the wants and needs of users. Personas do not represent the whole range of user diversity. However, they enable planners and developers to deal realistically with the situations and mobility needs of the relevant groups of people and allow specific analyses to implement user-oriented transport solutions. This paper outlines the methodology applied and the results achieved to make them accessible to a broad professional audience. The project demonstrates that knowledgeably selected personas provide added value in developing technologies. They can also be employed in the further education and sensitisation of children and juveniles

Extending the scope of pooled analyses of individual patient biomarker data from heterogeneous laboratory platforms and cohorts using merging algorithms

Background: A common challenge in medicine, exemplified in the analysis of biomarker data, is that large studies are needed for sufficient statistical power. Often, this may only be achievable by aggregating multiple cohorts. However, different studies may use disparate platforms for laboratory analysis, which can hinder merging. Methods: Using circulating placental growth factor (PIGF), a potential biomarker for hypertensive disorders of pregnancy (HDP) such as preeclampsia, as an example, we investigated how such issues can be overcome by inter-platform standardization and merging algorithms. We studied 16,462 pregnancies from 22 study cohorts. PIGF measurements (gestational age >= 20 weeks) analyzed on one of four platforms: R & Systems, Alere (R) Triage, Roche (R) Elecsys or Abbott (R) Architect, were available for 13,429 women. Two merging algorithms, using Z-Score and Multiple of Median transformations, were applied. Results: Best reference curves (BRC), based on merged, transformed PIGF measurements in uncomplicated pregnancy across six gestational age groups, were estimated. Identification of HDP by these PIGF-BRCS was compared to that of platform-specific curves. Conclusions: We demonstrate the feasibility of merging PIGF concentrations from different analytical platforms. Overall BRC identification of HDP performed at least as well as platform-specific curves. Our method can be extended to any set of biomarkers obtained from different laboratory platforms in any field. Merged biomarker data from multiple studies will improve statistical power and enlarge our understanding of the pathophysiology and management of medical syndromes. (C) 2015 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved.Peer reviewe

Perinatal and 2-year neurodevelopmental outcome in late preterm fetal compromise: the TRUFFLE 2 randomised trial protocol

Introduction: Following the detection of fetal growth restriction, there is no consensus about the criteria that should trigger delivery in the late preterm period. The consequences of inappropriate early or late delivery are potentially important yet practice varies widely around the world, with abnormal findings from fetal heart rate monitoring invariably leading to delivery. Indices derived from fetal cerebral Doppler examination may guide such decisions although there are few studies in this area. We propose a randomised, controlled trial to establish the optimum method of timing delivery between 32 weeks and 36 weeks 6 days of gestation. We hypothesise that delivery on evidence of cerebral blood flow redistribution reduces a composite of perinatal poor outcome, death and short-term hypoxia-related morbidity, with no worsening of neurodevelopmental outcome at 2 years. Methods and analysis: Women with non-anomalous singleton pregnancies 32+0 to 36+6 weeks of gestation in whom the estimated fetal weight or abdominal circumference is <10th percentile or has decreased by 50 percentiles since 18-32 weeks will be included for observational data collection. Participants will be randomised if cerebral blood flow redistribution is identified, based on umbilical to middle cerebral artery pulsatility index ratio values. Computerised cardiotocography (cCTG) must show normal fetal heart rate short term variation (≥4.5 msec) and absence of decelerations at randomisation. Randomisation will be 1:1 to immediate delivery or delayed delivery (based on cCTG abnormalities or other worsening fetal condition). The primary outcome is poor condition at birth and/or fetal or neonatal death and/or major neonatal morbidity, the secondary non-inferiority outcome is 2-year infant general health and neurodevelopmental outcome based on the Parent Report of Children's Abilities-Revised questionnaire. Ethics and dissemination: The Study Coordination Centre has obtained approval from London-Riverside Research Ethics Committee (REC) and Health Regulatory Authority (HRA). Publication will be in line with NIHR Open Access policy. Trial registration number: Main sponsor: Imperial College London, Reference: 19QC5491. Funders: NIHR HTA, Reference: 127 976. Study coordination centre: Imperial College Healthcare NHS Trust, Du Cane Road, London, W12 0HS with Centre for Trials Research, College of Biomedical & Life Sciences, Cardiff University. IRAS Project ID: 266 400. REC reference: 20/LO/0031. ISRCTN registry: 76 016 200