Resonance Searches with an Updated Top Tagger

The performance of top taggers, for example in resonance searches, can be significantly enhanced through an increased set of variables, with a special focus on final-state radiation. We study the production and the decay of a heavy gauge boson in the upcoming LHC run. For constant signal efficiency, the multivariate analysis achieves an increased background rejection by up to a factor 30 compared to our previous tagger. Based on this study and the documentation in the Appendix we release a new HEPTopTagger2 for the upcoming LHC run. It now includes an optimal choice of the size of the fat jet, N-subjettiness, and different modes of Qjets.Comment: 26 page

Arthritis Is Developed in Borrelia-Primed And -Infected Mice Deficient of Interleukin-17

Interleukin-17 (IL-17) has been shown to participate in the development of Lyme arthritis in experimental mice. For example, neutralization of IL-17 with antibodies inhibits induction of arthritis in Borrelia-primed and -infected C57BL/6 wild-type mice. We hypothesized that mice lacking IL-17 would fail to develop Borrelia-induced arthritis. IL-17-deficient and wild-type C57BL/6 mice were primed with heat-inactivated Borrelia and then infected with viable spirochetes 3 weeks later. No swelling or major histopathological changes of the hind paws were detected in IL-17-deficient or wild-type mice that were primed with Borrelia or infected with viable spirochetes. By contrast, IL-17-deficient and wild-type mice that were primed and subsequently infected with heterologous Borrelia developed severe swelling and histopathological changes of the hind paws. In addition, Borrelia-primed and -infected IL-17-deficient mice exhibited elevated gamma-interferon (IFN-γ) levels in sera and increased frequencies of IFN-γ-expressing lymphocytes in popliteal lymph nodes compared to Borrelia-primed and -infected wild-type mice. These results demonstrate that IL-17 is not required for development of severe pathology in response to infection with Borrelia burgdorferi, but may contribute to disease through an interaction with IFN-γ

A scanning probe-based pick-and-place procedure for assembly of integrated quantum optical hybrid devices

Integrated quantum optical hybrid devices consist of fundamental constituents such as single emitters and tailored photonic nanostructures. A reliable fabrication method requires the controlled deposition of active nanoparticles on arbitrary nanostructures with highest precision. Here, we describe an easily adaptable technique that employs picking and placing of nanoparticles with an atomic force microscope combined with a confocal setup. In this way, both the topography and the optical response can be monitored simultaneously before and after the assembly. The technique can be applied to arbitrary particles. Here, we focus on nanodiamonds containing single nitrogen vacancy centers, which are particularly interesting for quantum optical experiments on the single photon and single emitter level.Comment: The following article has been submitted to Review of Scientific Instruments. After it is published, it will be found at http://rsi.aip.org

Panel: IS 2010 – Major Changes in The Information Systems Curriculum

IS 2010- Curriculum Guidelines for Undergraduate Degree Programs in Information Systems has been compiled under the auspices of the Association for Computing Machinery and the Association for Information Systems. As stated in its executive summary, “This curriculum revision represents an effort to re-evaluate the core principles of the discipline through a very careful specification of the degree learning outcomes.” Indeed, the curriculum has outlined a substantial redirection of the information systems degree. It focuses much more heavily on improving organizational processes and viewing information systems in an enterprise interpretation. Technical knowledge and skills are still present but receive far less emphasis. Other topics, such as enterprise architecture, are introduced for which no current text is available. Implementing the 2010 core course curriculum could well change the learning objectives of a school’s information systems degree. The panelists will briefly describe the 2010 curriculum and compare it to the 2002 curriculum. Core classes will be evaluated using Bloom’s taxonomy for levels of knowledge. The 2010 curriculum will be evaluated for how it supports the IS major, specializations within the major, and an IS minor. The second half of the panel will be devoted to questions and answers between the panelists and the audience

A software for online monitoring of orientation-compensated forces during CI insertion

The electrode array insertion is a critical point during CI surgery and should be performed as gently as possible to preserve residual hearing. In order to measure occurring forces, an insertion tool with an integrated force sensor and an inertial measurement unit (IM U) is being developed. The weight of the electrode holder and the sensor add an unknown offset to the measured forces, depending on the tool orientation. To address this problem, a software which calculates the orientation-induced error and computes a corrected force was developed. The software was written in C++ using the library Qt 5.12.9. For maximization of the computing frequency, the data acquisition of both sensors and the monitoring was parallelized. An algorithm was developed to calculate the error caused by the electrode holder and sensor. For this purpose both weights were determined in a calibration procedure and merged with the provided IM U data. The evaluation was done in two test series (each n=5) with different initial tool orientations. To this end a stepwise 360° rotation around the horizontal axis was performed, while recording the corrected forces. The developed software allows a computing frequency up to 100 Hz with a latency of 10 ms for the online monitoring of the processed data. The evaluation of the corrected force shows a residual error of 0.347 mN ± 0.325 mN for the first and 0.176 mN ± 1.971 mN for the second test series. With the created algorithm, the impact of the extra weight on the sensor can be almost fully equalized. The highly responsive software offers a new possibility to process insertion forces and provide feedback to surgeons. Determining the influence of the tool orientation on the corrected forces is the subject of future researches

Web 2.0 Technologies in the Classroom

Today\u27s students make frequent use of Web 2.0 tools in their lives. Facebook and MySpace are used for social networking, Flickr and YouTube are used for sharing pictures and videos, and IM and text messaging are used for staying in touch with family and friends. Yet we live in a time when student interest in IT careers has significantly declined. University students often don\u27t see the connection between the software they use on a day-to-day basis, and a meaningful career in IT. This panel will present four approaches to applying Web 2.0 technologies in the classroom. Following a brief technology overview, Google Docs and Wikis will be presented as a means to facilitate student and faculty collaboration in the learning process. Panelists will also discuss the application of the virtual world Second Life, radical decentralization technologies (e.g. BitTorrent, del.icio.us, and Flickr), and social networking sites Facebook and LinkedIn

Enhancement of the Zero Phonon Line emission from a Single NV-Center in a Nanodiamond via Coupling to a Photonic Crystal Cavity

Using a nanomanipulation technique a nanodiamond with a single nitrogen vacancy center is placed directly on the surface of a gallium phosphide photonic crystal cavity. A Purcell-enhancement of the fluorescence emission at the zero phonon line (ZPL) by a factor of 12.1 is observed. The ZPL coupling is a first crucial step towards future diamond-based integrated quantum optical devices