309 research outputs found

    Hot Isostatic Press (Hip) Vitrification of Radwaste Concretes

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    Properly formulated and properly ``canned`` radwaste concretes can be readily hot-isostatically-pressed (HIPed) into materials that exhibit performance equivalent to typical radwaste-type glasses. The HIPing conditions (temperature/pressure) required to turn a concrete waste form into a ``vitrified`` waste form are quite mild and therefore consistent with both safety and high productivity. This paper describes the process and its products with reference to its potential application to Idaho Chemical Processing Plant (ICPP) reprocessing wastes

    Insights into a dinoflagellate genome through expressed sequence tag analysis

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    BACKGROUND: Dinoflagellates are important marine primary producers and grazers and cause toxic "red tides". These taxa are characterized by many unique features such as immense genomes, the absence of nucleosomes, and photosynthetic organelles (plastids) that have been gained and lost multiple times. We generated EST sequences from non-normalized and normalized cDNA libraries from a culture of the toxic species Alexandrium tamarense to elucidate dinoflagellate evolution. Previous analyses of these data have clarified plastid origin and here we study the gene content, annotate the ESTs, and analyze the genes that are putatively involved in DNA packaging. RESULTS: Approximately 20% of the 6,723 unique (11,171 total 3'-reads) ESTs data could be annotated using Blast searches against GenBank. Several putative dinoflagellate-specific mRNAs were identified, including one novel plastid protein. Dinoflagellate genes, similar to other eukaryotes, have a high GC-content that is reflected in the amino acid codon usage. Highly represented transcripts include histone-like (HLP) and luciferin binding proteins and several genes occur in families that encode nearly identical proteins. We also identified rare transcripts encoding a predicted protein highly similar to histone H2A.X. We speculate this histone may be retained for its role in DNA double-strand break repair. CONCLUSION: This is the most extensive collection to date of ESTs from a toxic dinoflagellate. These data will be instrumental to future research to understand the unique and complex cell biology of these organisms and for potentially identifying the genes involved in toxin production

    Completing College: National and State Reports

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    The national six-year college completion rate reached 62.2 percent, a 1.2 percentage point increase from last year. The completion rate increased regardless of starting institution types. Two-thirds of states increased at least 1 percentage point in completion rates over last year.This is the tenth report in the Completing College report series, featuring the completion rate trends nationally and for states, updated with the fall 2015 entering cohort's outcomes tracked through June 2021.The new longitudinal data dashboard offers national and multi-state comparisons through interactive visualizations and analysis tools. Underlying data are available online for downloading. The national eight-year completion rates are not included in the current report and will be published at a later time

    University American Sign Language Learners: Longitudinal Self- and Faculty Evaluation Ratings

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    Students who are Deaf or hard of hearing (D/HH) represent a small yet diverse population of students with individual needs who often receive educational services provided by sign language interpreters and teachers of the Deaf/hard of hearing (D/HH). Many interpreters and teachers appear unprepared to model fluent American Sign Language (ASL) skills when working with D/HH students who use sign language for communication and instruction. We investigated the ASL skills of 19 interpreting and Deaf education candidates within one university preparation program at two points in time: the end of ASL I class (Time 1) and a year later at the end of ASL IV (Time 2). We used video recordings of candidates’ signed renditions of a picture book, a rubric of 12 sign language indicators with five levels of proficiency across each indicator, and ratings conducted independently by the candidates and the five authors. Four of these authors were university professors in two different Deaf education/interpreting preparation programs and the fifth was a teacher at a residential school for the Deaf. Three have typical hearing and use ASL as a secondary language; two are Deaf and use ASL as their primary language. We compared candidates’ self-ratings to those of the five authors. We found that candidates tended to over-estimate their skills at T1; self-ratings and author ratings increased from T1 to T2, and candidates had higher agreement with most authors at T2 compared to T1. In addition, we found differences among ratings between the university faculty and the high school teacher. We discuss these differences in our findings and address implications for evaluating and improving university candidates’ ASL skills

    Group descent algorithms for nonconvex penalized linear and logistic regression models with grouped predictors

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    Penalized regression is an attractive framework for variable selection problems. Often, variables possess a grouping structure, and the relevant selection problem is that of selecting groups, not individual variables. The group lasso has been proposed as a way of extending the ideas of the lasso to the problem of group selection. Nonconvex penalties such as SCAD and MCP have been proposed and shown to have several advantages over the lasso; these penalties may also be extended to the group selection problem, giving rise to group SCAD and group MCP methods. Here, we describe algorithms for fitting these models stably and efficiently. In addition, we present simulation results and real data examples comparing and contrasting the statistical properties of these methods

    Heritability and impact of environmental effects during pregnancy on antral follicle count in cattle

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    peer-reviewedPrevious studies have documented that ovarian antral follicle count (AFC) is positively correlated with number of healthy follicles and oocytes in ovaries (ovarian reserve), as well as ovarian function and fertility in cattle. However, environmental factors (e.g., nutrition, steroids) during pregnancy in cattle and sheep can reduce AFC in offspring. The role that genetic and environmental factors play in influencing the variability in AFC and, correspondingly, the size of the ovarian reserve, ovarian function, and fertility, are, however, poorly understood. The present study tests the hypothesis that variability in AFC in offspring is influenced not only by genetic merit but also by the dam age and lactation status (lactating cows vs. nonlactating heifers) and milk production during pregnancy. Antral follicle count was assessed by ultrasonography in 445 Irish Holstein-Friesian dairy cows and 522 US Holstein-Friesian dairy heifers. Heritability estimates for AFC (± standard error) were 0.31 ± 0.14 and 0.25 ± 0.13 in dairy cows and heifers, respectively. Association analysis between both genotypic sire data and phenotypic dam data with AFC in their daughters was performed using regression and generalized linear models. Antral follicle count was negatively associated with genetic merit for milk fat concentration. Also, AFC was greater in offspring of dams that were lactating (n = 255) compared with nonlactating dams (n = 89) during pregnancy and was positively associated with dam milk fat concentration and milk fat-to-protein ratio. In conclusion, AFC in dairy cattle is a moderately heritable genetic trait affected by age or lactation status and milk quality but not by level of dam’s milk production during pregnancy

    Centrality dependence of charged-particle pseudorapidity distributions from d+Au collisions at sqrt(s_{NN})=200 GeV

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    Charged-particle pseudorapidity densities are presented for the d+Au reaction at sqrt{s_{NN}}=200 GeV with -4.2 <= eta <= 4.2$. The results, from the BRAHMS experiment at RHIC, are shown for minimum-bias events and 0-30%, 30-60%, and 60-80% centrality classes. Models incorporating both soft physics and hard, perturbative QCD-based scattering physics agree well with the experimental results. The data do not support predictions based on strong-coupling, semi-classical QCD. In the deuteron-fragmentation region the central 200 GeV data show behavior similar to full-overlap d+Au results at sqrt{s_{NN}}=19.4 GeV.Comment: 4 pages, 3figures; expanded discussion of uncertainties; added 60-80% centrality range; added additional discussion on centrality selection bia

    Scanning the phases of QCD with BRAHMS

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    BRAHMS has the ability to study relativistic heavy ion collisions from the final freeze-out of hadrons all the way back to the initial wave-function of the gold nuclei. This is accomplished by studying hadrons with a very wide range of momenta and angles. In doing so we can scan various phases of QCD, from a hadron gas, to a quark gluon plasma and perhaps to a color glass condensate.Comment: 8 pages, 6 figures, proceedings of plenary talk at Quark Matter 2004 conferenc
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