Attitudes towards big data practices and the institutional framework of privacy and data protection - A population survey (KIT Scientific Reports ; 7753)

A survey of the German population addressed attitudes towards scenarios of big data practices, i.e. price discrimination in retail, credit scoring, differentiations in health insurance and in employment, with features of using internet data, automated decision-making, and selling of data. The study analysed behavioural adaptations, protection measures, relations to demographics, personal value orientations, knowledge about computers, and attitudes about privacy and data protection

Beyond IQ: A latent state-trait analysis of general intelligence, dynamic decision making, and implicit learning

The present study investigated cognitive performance measures beyond IQ. In particular, we investigated the psychometric properties of dynamic decision making variables and implicit learning variables and their relation with general intelligence and professional success. N = 173 employees from different companies and occupational groups completed two standard intelligence tests, two dynamic decision making tasks, and two implicit learning tasks at two measurement occasions each. We used structural equation models to test latent state-trait measurement models and the relation between constructs. The results suggest that dynamic decision making and implicit learning are substantially related with general intelligence. Furthermore, general intelligence is the best predictor for income, social status, and educational attainment. Dynamic decision making can predict supervisor ratings even beyond general intelligence

Fluid Intelligence Is (Much) More than Working Memory Capacity: An Experimental Analysis

Empirical evidence suggests a great positive association between measures of fluid intelligence and working memory capacity, which implied to some researchers that fluid intelligence is little more than working memory. Because this conclusion is mostly based on correlation analysis, a causal relationship between fluid intelligence and working memory has not yet been established. The aim of the present study was therefore to provide an experimental analysis of this relationship. In a first study, 60 participants worked on items of the Advanced Progressive Matrices (APM) while simultaneously engaging in one of four secondary tasks to load specific components of the working memory system. There was a diminishing effect of loading the central executive on the APM performance, which could explain 15% of the variance in the APM score. In a second study, we used the same experimental manipulations but replaced the dependent variable with complex working memory span tasks from three different domains. There was also a diminishing effect of the experimental manipulation on span task performance, which could now explain 40% of the variance. These findings suggest a causal effect of working memory functioning on fluid intelligence test performance, but they also imply that factors other than working memory functioning must contribute to fluid intelligence

SpaceMaze: Incentivizing Correct Mobile Crowdsourced Sensing Behavior with a Sensified Minigame

Modern mobile phones are equipped with many sensors, which can increasingly be used to sense various environmental phenomena. In particular, mobile sensing has enabled crowdsourced data collection at an unprecedented scale. However, as laypersons are involved in this, concerns regarding the data quality arise. This work explores the gamification of smartphone-based measurement processes in practice by embedding a sensing task into a mobile minigame. The underlying idea is — rather than to educate the user on how to correctly perform a measurement task — to opportunistically execute the measurement in the background once the smartphone is in a suitable context. To this end, this paper presents the design and evaluation of SpaceMaze, a smartphone game with the goal of minimizing user error by introducing appropriate game mechanics to influence the phone context, using the example of mobile noise level monitoring. A large user study that compares SpaceMaze to two non-gamified apps for noise level monitoring (N=360 in total) shows that SpaceMaze can successfully reduce user errors when compared to simple non-gamified ambient noise level monitoring applications and that the minigame is generally perceived as being enjoyable. Solutions for remaining problems, such as noise generated by the players, are discussed

Analysis of shared heritability in common disorders of the brain

ience, this issue p. eaap8757 Structured Abstract INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological comorbidity, inciting debate about their etiologic overlap. However, detailed study of phenotypes with different ages of onset, severity, and presentation poses a considerable challenge. Recently developed heritability methods allow us to accurately measure correlation of genome-wide common variant risk between two phenotypes from pools of different individuals and assess how connected they, or at least their genetic risks, are on the genomic level. We used genome-wide association data for 265,218 patients and 784,643 control participants, as well as 17 phenotypes from a total of 1,191,588 individuals, to quantify the degree of overlap for genetic risk factors of 25 common brain disorders. RATIONALE Over the past century, the classification of brain disorders has evolved to reflect the medical and scientific communities' assessments of the presumed root causes of clinical phenomena such as behavioral change, loss of motor function, or alterations of consciousness. Directly observable phenomena (such as the presence of emboli, protein tangles, or unusual electrical activity patterns) generally define and separate neurological disorders from psychiatric disorders. Understanding the genetic underpinnings and categorical distinctions for brain disorders and related phenotypes may inform the search for their biological mechanisms. RESULTS Common variant risk for psychiatric disorders was shown to correlate significantly, especially among attention deficit hyperactivity disorder (ADHD), bipolar disorder, major depressive disorder (MDD), and schizophrenia. By contrast, neurological disorders appear more distinct from one another and from the psychiatric disorders, except for migraine, which was significantly correlated to ADHD, MDD, and Tourette syndrome. We demonstrate that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine. We also identify significant genetic sharing between disorders and early life cognitive measures (e.g., years of education and college attainment) in the general population, demonstrating positive correlation with several psychiatric disorders (e.g., anorexia nervosa and bipolar disorder) and negative correlation with several neurological phenotypes (e.g., Alzheimer's disease and ischemic stroke), even though the latter are considered to result from specific processes that occur later in life. Extensive simulations were also performed to inform how statistical power, diagnostic misclassification, and phenotypic heterogeneity influence genetic correlations. CONCLUSION The high degree of genetic correlation among many of the psychiatric disorders adds further evidence that their current clinical boundaries do not reflect distinct underlying pathogenic processes, at least on the genetic level. This suggests a deeply interconnected nature for psychiatric disorders, in contrast to neurological disorders, and underscores the need to refine psychiatric diagnostics. Genetically informed analyses may provide important "scaffolding" to support such restructuring of psychiatric nosology, which likely requires incorporating many levels of information. By contrast, we find limited evidence for widespread common genetic risk sharing among neurological disorders or across neurological and psychiatric disorders. We show that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures. Further study is needed to evaluate whether overlapping genetic contributions to psychiatric pathology may influence treatment choices. Ultimately, such developments may pave the way toward reduced heterogeneity and improved diagnosis and treatment of psychiatric disorders

Genome-wide identification and phenotypic characterization of seizure-associated copy number variations in 741,075 individuals

Copy number variants (CNV) are established risk factors for neurodevelopmental disorders with seizures or epilepsy. With the hypothesis that seizure disorders share genetic risk factors, we pooled CNV data from 10,590 individuals with seizure disorders, 16,109 individuals with clinically validated epilepsy, and 492,324 population controls and identified 25 genome-wide significant loci, 22 of which are novel for seizure disorders, such as deletions at 1p36.33, 1q44, 2p21-p16.3, 3q29, 8p23.3-p23.2, 9p24.3, 10q26.3, 15q11.2, 15q12-q13.1, 16p12.2, 17q21.31, duplications at 2q13, 9q34.3, 16p13.3, 17q12, 19p13.3, 20q13.33, and reciprocal CNVs at 16p11.2, and 22q11.21. Using genetic data from additional 248,751 individuals with 23 neuropsychiatric phenotypes, we explored the pleiotropy of these 25 loci. Finally, in a subset of individuals with epilepsy and detailed clinical data available, we performed phenome-wide association analyses between individual CNVs and clinical annotations categorized through the Human Phenotype Ontology (HPO). For six CNVs, we identified 19 significant associations with specific HPO terms and generated, for all CNVs, phenotype signatures across 17 clinical categories relevant for epileptologists. This is the most comprehensive investigation of CNVs in epilepsy and related seizure disorders, with potential implications for clinical practice

Befunde aus EEG-Untersuchungen zum Mentalen Training

Mentales Training (MT) im Sinne der planmäßig wiederholten Vorstellung eines Bewegungsablaufes ist ein zentraler Gegenstand sportpsychologischer Forschung. Im Hochleistungssport und in der Rehabilitation wird es zur Optimierung von Bewegungen eingesetzt. Einen Erklärungsansatz der Trainingswirkung bietet die Simulationstheorie mit dem zentralen Postulat, dass Bewegungsausführung und -vorstellung gleiche neuronale Strukturen aktivieren (funktionale Äquivalenz). Diese Annahme wurde mittels verschiedener neurophysiologischer Methoden geprüft, die teils zu widersprüchlichen Befunden führten. Die Elektroenzephalographie (EEG) kann unserer Ansicht nach dabei helfen, Lücken im theoretischen Erkenntnisprozess zu schließen. In diesem Artikel geben wir einen Überblick über die aktuelle Befundlage zum Mentalen Training mittels EEG. Es sollen drei wesentliche Vorteile der Methode aufgezeigt werden: (a) das EEG liefert Maße der neurophysiologischen Aktivität mit hoher zeitlicher Auflösung, (b) technische Weiterentwicklungen (drahtlose Hardware, tragbare Ausrüstung) erlauben die notwendige Bewegungsfreiheit für eine Anwendung im Sportkontext und (c) in der Rehabilitation kann die Vorstellung von Bewegungen als mentale Strategie dienen, um eine Neuroprothese auf Basis von Hirnsignalen zu steuern. </jats:p

Localization of temporal preparation effects via trisected reaction time

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