Development of an Inter-professional Root Cause Analysis Workshop within a Required Medication Safety Course

Purpose: To present the development/delivery of an Interprofessional Root Cause Analysis (RCA) Workshop by colleges of pharmacy and nursing at a health sciences university. Background: Hospitals and regulatory agencies emphasize the significance of patient safety and recommend that medication/patient safety principles be introduced in health care professions’ education. A college of pharmacy’s required Medication Safety course introduces essential content on principles including culture of medication safety, error reporting systems, medication error causes and technology’s influence on errors. One key course element is completing a team-based RCA. This assignment was completed solely by Pharm.D. students (fall 2009-2014). Given increased emphasis on IPE, pharmacy faculty partnered with nursing to deliver the program to both disciplines in fall 2015. Description of program: This 2-hour, interprofessional workshop was incorporated into the Medication Safety course for ~ 75 pharmacy students and a required Medical Surgical Clinical Management II course for ~ 125 nursing students. Preliminary findings: Overall performance during this RCA Workshop was high. Each team accurately identified the medication error present in their assigned case. Survey results illustrated that 98% of students agreed/strongly agreed that the workshop contributed to their learning by creating an experience emphasizing the importance of interprofessional teamwork in preventing medication errors. Relevance to interprofessional education or practice: Given the significant roles and responsibilities of pharmacists and nurses in the medication use process, this RCA Workshop was created to mimic a “real world” medication safety healthcare team. Participation enhanced student comprehension and application of medication safety principles and awareness of the roles and contributions of the different health professionals. Recommendations for future investigation and/or incorporation into education and/or practice settings: The faculty will conduct this program again to assess outcomes linked to core competencies for Interprofessional Collaborative Practice (i.e. values/ethics, communication). The long-term goal is to include additional health professions students. Session Learning Objectives: The audience will be able to describe how a novel, collaborative Inter-professional RCA Workshop was used to facilitate inter-professional learning. Describe how a RCA workshop may be able to assist students in meeting IPEC Core Competencies

Incidence and Severity of Drug Interactions Before and After Switching Antiretroviral Therapy to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Treatment-Experienced Patients.

Background: Switching antiretroviral therapy (ART) in people with HIV (PWH) can influence their risk for drug-drug interactions (DDIs). The purpose of this study was to assess changes in the incidence and severity of DDIs among PWH who switched their ART to bictegravir/emtricitabine/tenofovir alafenamide (BIC/FTC/TAF). Methods: This was a multicenter retrospective cohort study of PWH on ART and at least 1 concomitant medication (CM) who switched to BIC/FTC/TAF between 3/2018 and 6/2019. Using the University of Liverpool\u27s HIV Drug Interaction Database, 2 DDI analyses were performed for each patient. The first assessed patients\u27 preswitch ART regimens with their CM list. The second assessed the same CM list with BIC/FTC/TAF. Each ART-CM combination was given a score of 0 (no or potential weak interaction), 1 (potential interaction), or 2 (contraindicated interaction). A paired Results: Among 411 patients, 236 (57%) had at least 1 DDI present at baseline. On average, baseline DDI scores (SD) were 1.4 (1.8) and decreased by 1 point (95% CI, -1.1 to -0.8) after patients switched to BIC/FTC/TAF ( Conclusions: Treatment-experienced PWH eligible to switch their ART may experience significant declines in number and severity of DDIs if switched to BIC/FTC/TAF

Outcomes of Third-Year Pharmacy Students Using Technology for Instruction in an Infectious Diseases Elective Course

BACKGROUND The use of technology both inside and outside the classroom is integral to the facilitation of pharmacy students’ learning.1 Technology is allowing education to restructure classroom time for something other than simple transmission of factual information and to adopt an evidence-based approach to instructional innovation and reform.1 Pharmacy colleges and schools should incorporate technologies that students frequently use and that positively impact learning.2 Limited assessment of the impact of technology on student performance is available including teaching and learning from peers.1,2 An infectious diseases elective course developed at the Jefferson School of Pharmacy incorporated the use of contemporary technology to facilitate student learning and peer-generated instruction

Are patients living with HIV infection at risk for not receiving statin medications for cardiovascular disease risk reduction?

Objective To determine the prevalence of appropriate statin prescribing for ASCVD risk reduction in PLWHhttps://jdc.jefferson.edu/pharmacyposters/1011/thumbnail.jp

The incidence and severity of drug interactions before and after antiretroviral therapy simplification in treatment experienced patients with HIV Infection

Purpose The primary objective of this study was to assess changes in the incidence and severity of drug interactions before and after ART simplification in treatment experienced patients. Describe ART medication class changes and analyze predictors for achieving drug interaction score reductions.https://jdc.jefferson.edu/pharmacyposters/1012/thumbnail.jp

The Incidence and Severity of Drug Interactions Before and After Switching Antiretroviral Therapy to Bictegravir/Emtricitabine/Tenofovir alafenamide in Treatment Experienced Patients

Objective The primary outcome was to measure the proportion of patients experiencing DIs before and after the ART switch. The secondary outcome was to measure changes in DI scores before and after the ART switch.https://jdc.jefferson.edu/pharmacyposters/1021/thumbnail.jp

A Real World Assessment of the Efficacy and Safety of Switching from TDF to TAF in Treatment Experienced Patients with HIV Infection

Objective The primary objective of this study was to determine if patients maintain viral suppression after switching from TDF to TAF The secondary objective was to assess changes in renal function and serum cholesterol levelshttps://jdc.jefferson.edu/pharmacyposters/1019/thumbnail.jp

Exploring the Prevalence and Characteristics Associated with Weight Gain and Metabolic Changes in PLWH who are Virologically Suppressed on Antiretroviral Therapy and Switch to Integrase Inhibitor Containing Regimens

Objectives To determine the prevalence, extent and characteristics of weight gain among virologically suppressed PLWH whose ART has been switched to an INSTI-containing regimen To examine the presence of metabolic changes in PLWH who have been switched to INSTI-containing ARThttps://jdc.jefferson.edu/pharmacyposters/1017/thumbnail.jp