Non-Thermal Electromagnetic Radiation Damage to Lens Epithelium

High frequency microwave electromagnetic radiation from mobile phones and other modern devices has the potential to damage eye tissues, but its effect on the lens epithelium is unknown at present. The objective of this study was to investigate the non-thermal effects of high frequency microwave electromagnetic radiation (1.1GHz, 2.22 mW) on the eye lens epithelium in situ. Bovine lenses were incubated in organ culture at 35°C for 10-15 days. A novel computer-controlled microwave source was used to investigate the effects of microwave radiation on the lenses. 58 lenses were used in this study. The lenses were divided into four groups: (1) Control lenses incubated in organ culture for 10 to15 days. (2) Electromagnetic radiation exposure group treated with 1.1 GHz, 2.22 mW microwave radiation for 90 cycles of 50 minutes irradiation followed by 10 minutes pause and cultured up to 10 days. (3) Electromagnetic radiation exposure group treated as group 2 with 192 cycles of radiation and cultured for 15 days. (4) Lenses exposed to 39.5ºC for 2 hours 3 times with 24 hours interval after each treatment beginning on the second day of the culture and cultured for 11 days. During the culture period, lens optical quality was followed daily by a computer-operated scanning laser beam. At the end of the culture period, control and treated lenses were analyzed morphologically and by assessment of the lens epithelial ATPase activity. Exposure to 1.1 GHz, 2.22 mW microwaves caused a reversible decrease in lens optical quality accompanied by irreversible morphological and biochemical damage to the lens epithelial cell layer. The effect of the electromagnetic radiation on the lens epithelium was remarkably different from those of conductive heat. The results of this investigation showed that electromagnetic fields from microwave radiation have a negative impact on the eye lens. The lens damage by electromagnetic fields was distinctly different from that caused by conductive heat

Beam-Wave Interaction in Periodic and Quasi-Periodic Structures

The main theme of this book is the interaction of electrons with electromagnetic waves in the presence of periodic and quasi-periodic structures in vacuum, in view of applications in the design and operation of particle accelerators. The first part of the book is concerned with the textbook-like presentation of the basic material, in particular reviewing elementary electromagnetic phenomena and electron dynamics. The second part of the book describes the current models for beam-wave interactions with periodic and quasi-periodic structures. This is the basis for introducing, in the last part of the book, a number of particle and radiation sources that rest on these principles, in particular the free-electron laser, wake-field acceleration schemes and a number of other advanced particle accelerator concepts. This second edition brings this fundamental text up-to-date in view of the enormous advances that have been made over the last decade since the first edition was published. All chapters, as well as the bibliography, have been significantly revised and extended, and the number of end-of-chapter exercises has been further increased to enhance this book’s usefulness for teaching specialized graduate courses.

Radial Kick in High-Efficiency Output Structures

We have developed an analytical approach that predicts radial oscillation near the aperture of a pillbox cavity. In addition, it provides natural criteria for the design of a tapered guiding magnetic field in the output section of a relativistic klystron amplifier, as well as that of a travelling wave tube, in a method that is self-consistent with the dynamics of the electrons

Linear analysis of active-medium two-beam accelerator

We present detailed development of the linear theory of wakefield amplification by active medium and its possible application to a two-beam accelerator (TBA) is discussed. A relativistic train of triggering microbunches traveling along a vacuum channel in an active medium confined by a cylindrical waveguide excites Cherenkov wake in the medium. The wake is a superposition of azimuthally symmetric transverse magnetic modes propagating along a confining waveguide, with a phase velocity equal to the velocity of the triggering bunches. The structure may be designed in such a way that the frequency of one of the modes is close to active-medium resonant frequency, resulting in amplification of the former and domination of a single mode far behind the trigger bunches. Another electron bunch placed in proper phase with the amplified wakefield may be accelerated by the latter. Importantly, the energy for acceleration is provided by the active medium and not the drive bunch as in a traditional TBA. Based on a simplified model, we analyze extensively the impact of various parameters on the wakefield amplification process

Optimized operation of dielectric laser accelerators: Single bunch

We introduce a general approach to determine the optimal charge, efficiency and gradient for laser driven accelerators in a self-consistent way. We propose a way to enhance the operational gradient of dielectric laser accelerators by leverage of beam-loading effect. While the latter may be detrimental from the perspective of the effective gradient experienced by the particles, it can be beneficial as the effective field experienced by the accelerating structure, is weaker. As a result, the constraint imposed by the damage threshold fluence is accordingly weakened and our self-consistent approach predicts permissible gradients of ∼10  GV/m, one order of magnitude higher than previously reported experimental results—with unbunched pulse of electrons. Our approach leads to maximum efficiency to occur for higher gradients as compared with a scenario in which the beam-loading effect on the material is ignored. In any case, maximum gradient does not occur for the same conditions that maximum efficiency does—a trade-off set of parameters is suggested

Optimized operation of dielectric laser accelerators: Multibunch

We present a self-consistent analysis to determine the optimal charge, gradient, and efficiency for laser driven accelerators operating with a train of microbunches. Specifically, we account for the beam loading reduction on the material occurring at the dielectric-vacuum interface. In the case of a train of microbunches, such beam loading effect could be detrimental due to energy spread, however this may be compensated by a tapered laser pulse. We ultimately propose an optimization procedure with an analytical solution for group velocity which equals to half the speed of light. This optimization results in a maximum efficiency 20% lower than the single bunch case, and a total accelerated charge of 10^{6} electrons in the train. The approach holds promise for improving operations of dielectric laser accelerators and may have an impact on emerging laser accelerators driven by high-power optical lasers

Thermal scaling laws of the optical Bragg acceleration structure

The temperature distribution and heat flow in the planar optical Bragg acceleration structure, fed by a train of high-power laser pulses, are analyzed. Dynamic analysis of a high-repetition rate train of pulses indicates that the stationary solution is an excellent approximation for the regime of interest. Analytic expressions for the temperature and heat distributions across the acceleration structure are developed. Assuming an accelerating gradient of 1  GV/m and a loss factor similar to that existing in communication optical fibers 1   dB/km (tan⁡δ∼10^{-11}), the temperature increase is less than 1 K and the heat flow is of the order of 1   W/cm^{2}, which is 3 orders of magnitude lower than the known technological limit for heat dissipation. Obviously, using materials with a significantly higher loss tangent may lead to unacceptable temperatures and temperature gradients as well as confinement difficulties and phase mismatch