Succesful Treatment With Acar Compression Sutures On Late Postpartum Hemorrhage Due To The Placenta Accreata; Case Report

Plasenta yapışma anomalileri, plasentanın uterin duvar içine doğru anormal şekilde invaze olmasıdır. Plasenta akreata, inkreata ve perkreata olmak üzere 3 grupta incelenir. Burada plasenta akreata nedeniyle postpartum 17. günde başlayan ciddi postpartum kanamanın tedavisinde kullanılan yeni sütür tekniği (Acar usulü kompresyon sütürü) ile tedavi edilen bir olgu sunulmuştur. Hasta 17 gün önce dış merkezde vajinal doğum yapmış ve postpartum 17. günde gelişen abondan vajinal kanama nedeniyle kliniğimize sevk edilmiştir. Ultrason ve litotomi pozliyonunda yapılan jinekolojik muayenesinde kavitede uterus korpus ön duvarda yaklaşık olarak 3x4 cm boyutlarında uterusa dens olarak yapışmış doku palpe edilmiştir. Abondan vajinal kanaması olan hastaya laparotomi ve histerotomi yapılmış, çıkarılan plasental doku sonrası plasental yataktan gözlenen ciddi kanama Acar Usulü Kompresyon Sütürü konularak kontrol edilmiştirPlacental adhesion disorders are the abnormal invasions of the placenta into the uterin wall.These disorders are examined in three groups;increata ,accreata and percreata.These conditions may lead to serious complications.In this case a patient presented with severe postpartum hemorrhage on the 17th day due to p.accreta was treated with a new suture technique (Acar style compression suture ).The patient had vaginal delivery in another center 17 days ago and referred to our center because of severe vaginal hemorrhage on 17th day of postpartum.In vaginal examination performed in the lithotomy position the servix was found approximately 2 cm open ,the cavity was examined under sterile conditions and approximately 3x4 cm adhesive tissue was palpeted in the anterior wall.Emergency laparotomy decision was made and histeretomy was performed. After the placental tissue was taken out, serious hemorrhage observed in the placental bad was controlled by placing the Acar style compression sutur

Assessment of oxidant-antioxidant status alterations with tumor biomarkers and reproductive system hormones in uterine MYOMAS.

Objectives: Uterine myomas (UM) are responsible for significant morbidity and have adverse effects on quality of life in women. Reactive oxygen species (ROS) and antioxidant enzymes (AOE), as well as sex steroids play important roles in the reproductive physiology processes. Thus, we aimed to investigate the role of oxidant-antioxidant status in UM by measuring the AOE activities and lipid peroxidation (LPO) levels. This is the first study assessing these parameters together in UM based on also menopausal status and evaluating possible correlations between AOE activities, LPO markers, tumor biomarkers, female reproductive system hormone levels, comprehensively. Study design: The study group consisted of patients who have undergone surgical resection with confirmed pathology of uterine myoma (UM, n = 25) and divided into subgroups; premenopausal (UMpre) and postmenopausal (UMpost). Erythrocyte copper-zinc superoxide dismutase (Cu,Zn-SOD), catalase (CAT), glutathione peroxidase (GPx1) activities were measured along with plasma malondialdehyde (MDA) and urinary 8-epi-prostaglandin F2α (8-epi-PGF2α) levels in patients with UM. The obtained data were compared to the data of healthy individuals (C, n = 25) and its subgroups; premenopausal (Cpre) and postmenopausal (Cpost). Results: All AOE activities were higher (∼40% for Cu,Zn-SOD, p = 0.003; ∼55% for CAT, p = 0.001; ∼15% for GPx1, p = 0.169) and the LPO levels were lower (∼60% for MDA, p = 0.011 and ∼45% for 8-epi-PGF2α, p = 0.055) in patients with UM vs control. Approximately similar alterations were observed in UMpre vs Cpre and in UMpost vs Cpost. A significant negative correlation between erythrocyte Cu,Zn-SOD activity and plasma MDA levels (r = -0.431, p = 0.005) was reported. Conclusion: Decreased LPO levels might be the consequence of compensator high antioxidant enzyme activities against mild oxidative stress in the circulation of patients with UM. The marked negative correlation between erythrocyte Cu,Zn-SOD activity and plasma MDA levels also supported this finding

Assessment of oxidant-antioxidant status alterations with tumor biomarkers and reproductive system hormones in uterine MYOMAS

Objectives: Uterine myomas (UM) are responsible for significant morbidity and have adverse effects on quality of life in women. Reactive oxygen species (ROS) and antioxidant enzymes (AOE), as well as sex steroids play important roles in the reproductive physiology processes. Thus, we aimed to investigate the role of oxidant-antioxidant status in UM by measuring the AOE activities and lipid peroxidation (LPO) levels. This is the first study assessing these parameters together in UM based on also menopausal status and evaluating possible correlations between AOE activities, LPO markers, tumor biomarkers, female reproductive system hormone levels, comprehensively. Study Design: The study group consisted of patients who have undergone surgical resection with confirmed pathology of uterine myoma (UM, n = 25) and divided into subgroups; premenopausal (UM pre ) and postmenopausal (UM post ). Erythrocyte copper-zinc superoxide dismutase (Cu,Zn-SOD), catalase (CAT), glutathione peroxidase (GPx1) activities were measured along with plasma malondialdehyde (MDA) and urinary 8-epi-prostaglandin F2α (8-epi-PGF2α) levels in patients with UM. The obtained data were compared to the data of healthy individuals (C, n = 25) and its subgroups; premenopausal (C pre ) and postmenopausal (C post ). Results: All AOE activities were higher (∼40% for Cu,Zn-SOD, p = 0.003; ∼55% for CAT, p = 0.001; ∼15% for GPx1, p = 0.169) and the LPO levels were lower (∼60% for MDA, p = 0.011 and ∼45% for 8-epi-PGF2α, p = 0.055) in patients with UM vs control. Approximately similar alterations were observed in UM pre vs C pre and in UM post vs C post. A significant negative correlation between erythrocyte Cu,Zn-SOD activity and plasma MDA levels (r = -0.431, p = 0.005) was reported. Conclusion: Decreased LPO levels might be the consequence of compensator high antioxidant enzyme activities against mild oxidative stress in the circulation of patients with UM. The marked negative correlation between erythrocyte Cu,Zn-SOD activity and plasma MDA levels also supported this finding. © 201