FD ファシリテーター ヨウセイ ケンシュウ ノ コウカ ニ カンスル イチコウサツ : トクシマ ダイガク ニオケル FD ファシリテーター ノ ヤクワリ ト イギ

徳島大学では2002年度より教育革新FDプログラムが立ち上った。現在までに多様な全学FDプログラムが開発・実施されてきている。その中でも部局FDの組織化を目指した研修プログラム として部局FDを実質的に担当する教員を養成するためのFDファシリテーター養成研修を実施している。2008年度からは部局FD組織が実質的に機能し始め、全学的なFD実施組織と部局FDの連携が活発に実施されるようになりつつある。部局FDを推進する担い手となるFDファシリテーターの役割や存在意義は部局FD組織にとって、ますます重要なものになりつつあると考えられる。 FDファシリテーターはFD組織の発達にも関わるコアメンバーであり、実質的なFDの実践を続けていくためには、FDの専門性に加え、組織に関わる正統的成員(1)としての高い当事者意識が必要である。本研究の目的は、徳島大学におけるFDファシリテーターの役割とその意義に注目し、FDファシリテーター養成研修でのアンケート調査をもとに、効果検証を試みるものである。特に、2009年度の研修については、FDファシリテーターにとって重要な知識やスキルの獲得と、FDファシリテーターとしての当事者意識に関わる意欲や自信の変化に注目したところ、スキルアップと当事者意識の変容に関する効果が見られた。Since 2002，educational innovation has started through FD programs at the University of Tokushima. Until now various university-wide FD programs have been developed and conducted. The FD facilitator training program has been carried out to develop teachers who are responsible for FD in their respective departments. The Aim is to build up FD organizations in each department. Depaetment FD organizations have been incorporaled substantlally since 2008. We see elaborated collaboration between the university-wide FD organization and the departmenta FD organizations. The roles of the FD facilitator of each department as the core member to promote their departmental FD are becoming more important. To keep practicing substantial FD，they need to be conscious of their identity as the FD facilitator. They need to be actively involved in facilitating FD programs for their departments while maintaining a sense of ownership as an authentic member of the department.The aim of this paper is to discuss the importance of the FD facilitator program based on the results of the questionnaire survey conducted at the beginning and the end of FD facilitator training. To evaluate this program，we pay close attention to whether the participants are able to acquire FD skills and knowledge which are considered necessary. Futhermore focus on whether they demonstrated any attitudinal change in their motivation and confidence as FD facilitators

Activation-Induced Cytidine Deaminase Deficiency Causes Organ-Specific Autoimmune Disease

Activation-induced cytidine deaminase (AID) expressed by germinal center B cells is a central regulator of somatic hypermutation (SHM) and class switch recombination (CSR). Humans with AID mutations develop not only the autosomal recessive form of hyper-IgM syndrome (HIGM2) associated with B cell hyperplasia, but also autoimmune disorders by unknown mechanisms. We report here that AID−/− mice spontaneously develop tertiary lymphoid organs (TLOs) in non-lymphoid tissues including the stomach at around 6 months of age. At a later stage, AID−/− mice develop a severe gastritis characterized by loss of gastric glands and epithelial hyperplasia. The disease development was not attenuated even under germ-free (GF) conditions. Gastric autoantigen -specific serum IgM was elevated in AID−/− mice, and the serum levels correlated with the gastritis pathological score. Adoptive transfer experiments suggest that autoimmune CD4+ T cells mediate gastritis development as terminal effector cells. These results suggest that abnormal B-cell expansion due to AID deficiency can drive B-cell autoimmunity, and in turn promote TLO formation, which ultimately leads to the propagation of organ-specific autoimmune effector CD4+ T cells. Thus, AID plays an important role in the containment of autoimmune diseases by negative regulation of autoreactive B cells