Cytological Diagnosis of Primary Cutaneous Nocardiosis in a Known Case of Lepromatous Leprosy, Syphilis and HIV

Nocardiosis is an acute, subacute or chronic bacterial infection caused by a group of aerobic, gram positive and weakly acid fast species of genus Nocardia. Primary Cutaneous Nocardiosis (PCN) is relatively uncommon disease and is usually seen in immunocompetent persons. We report a case of primary cutaneous nocardiosis in a known case of lepromatous leprosy, syphilis and HIV patient who presented with painful swelling over right thigh

Phaeohyphomycosis Masquerading As Epidermal Cyst – A Diagnostic Dilemma in Immunocompetent Hosts and Review of Literature

Phaeohyphomycosis is caused by a rare dematiaceous, pigmented, mycelia forming fungi. It is an opportunistic fungal infection in immunocompromised hosts. It can present with varied clinical manifestations, as subcutaneous infection to widespread fulminant disseminated disease. Here we present three cases of subcutaneous phaeohyphomycosis in immunocompetent hosts at unusual site – popliteal fossa, great toe and sole of the foot. Awareness of unusual clinical presentation of Phaeohyphomycosis can lead to early diagnosis which may help in prevention of wide spread dissemination of disease and fatal outcome

Seromucinous Cystadenoma of Ovary – A Rare Case Report

Ovarian epithelial tumours are common diseases of female genital tract, they account for the majority of female ovarian neoplasms. The recent World Health Organization (WHO) 2014 classification of tumours of female reproductive Organs introduced a new category of ovarian neoplasm designated as “seromucinous tumours” as they exhibit both serous and mucinous features. These are uncommon ovarian tumours; here we report a rare case of seromucinous cystadenoma in a 27 year old female patient

New Methylene Blue Stain for Malaria Detection on Thin Smears

Background: Malaria is the most important parasitic infection of man. Microscopy remains gold standard in malaria diagnosis. Management of malaria requires rapid detection of parasite in human blood. Hence there is a need to develop another diagnostic method with less limitation, which will address this issue. Aim and Objectives: To find a low cost reliable and accurate method for malaria detection on peripheral smear. Material and Methods: A prospective study of 40 cases was done. Two thin smears were prepared for each case; one was stained with Leishman stain and other with new methylene blue stain and examined under oil immersion. The smears were examined individually by two pathologists and results were prepared. Different parasitic morphologic forms were looked for. Parasitemia percentage was calculated. We also compared number of fields required to diagnose with both stains in positive cases. Results: In this study we found that 25 (83.3%) cases were detected in less than 50 fields using New Methylene blue stain against 18 (60.0%) cases with Leishman stain. We also found 100% sensitivity and specificity for New Methylene blue stain, whereas Leishman stain showed 90% sensitivity and specificity of 85%. Conclusion: The detection of malaria parasite was considerably easy with New Methylene Blue stain and required less time in comparison with Leishman stain

Swelling of the Upper Lip...Not always a Mucous Retention Cyst!!

Schwannoma, also known as neurilemmoma, is a solitary benign tumour arising from the Schwann cells. Oral schwannomas are rare and upper lip is an uncommon site. The diagnosis of schwannoma is typically made on histopathology and surgical resection is the treatment of choice. We report a case of swelling of the upper lip in a 26 year old male which was clinically diagnosed as mucous retention cyst and on histopathological examination, a diagnosis of schwannoma was offered

Microfilaria Masquerding as Soft Tissue Neoplasm in Left Arm

Filariasis is endemic in India with large number of cases being reported every year. In endemic areas, filariasis may be entirely asymptomatic even with high microfilaraemia. We report an unusual case of filariasis in a 20 year old woman, who presented with a swelling in the medial aspect of the left upper arm since 6 months which was clinically suspected as a neoplastic lesion. On histopathological examination diagnosis of microfilaria was offered