68 research outputs found
ОПРЕДЕЛЕНИЕ КРАЕВОГО УГЛА СМАЧИВАНИЯ НА ПЛОСКИХ ПОВЕРХНОСТЯХ / М Г
The paper considers an improved technique for determination of a contact wetting angle. Description of the devices that make it possible to determine a contact wetting angle with due account of surface roughness is given in the paper. A specified formula for calculation of a contact wetting angle has been derived.Усовершенствована методика определения краевого угла смачивания. Приводится описание комплекса устройств, позволяющего определять краевой угол смачивания с учетом шероховатости поверхности. Получена уточненная формула для расчета краевого угла смачивания.
On charged impurity structures in liquid helium
The thermoluminescence spectra of impurity-helium condensates (IHC) submerged in superfluid helium have
been observed for the first time. Thermoluminescence of impurity-helium condensates submerged in superfluid
helium is explained by neutralization reactions occurring in impurity nanoclusters. Optical spectra of excited
products of neutralization reactions between nitrogen cations and thermoactivated electrons were rather different
from the spectra observed at higher temperatures, when the luminescence due to nitrogen atom recombination
dominates. New results on current detection during the IHC destruction are presented. Two different mechanisms
of nanocluster charging are proposed to describe the phenomena observed during preparation and warmup
of IHC samples in bulk superfluid helium, and destruction of IHC samples out of liquid helium
Вариант расчета экономической эффективности освоения новой техники, технологии и оборудования
The paper gives a variant of determination of economic efficiency while using new technique, technology and equipment under conditions of market economy. The calculation has been made for technological processes of machining steel, cast iron and aluminium alloy cases of automobile brake cylinders.Представлен вариант определения экономической эффективности при использовании новой техники, технологии и оборудования в условиях рыночной экономики. Расчет проведен для технологических процессов механической обработки корпусов автомобильных тормозных цилиндров, изготовленных из стали, чугуна и алюминиевого сплава
ПОЛУЧЕНИЕ ВЫСОКОПРОЧНЫХ ДЕФОРМИРУЕМЫХ АЛЮМИНИЕВЫХ СПЛАВОВ ТИПА АМг10
Traditional grades of aluminum alloys do not always meet the requirements of modern aerospace engineering. Al–Si foundry alloys possess insufficient mechanical strength characteristics and low plasticity due to their structural features (coarse brittle silicon inclusions and intermetallic phases). Therefore they cannot be exposed to pressure treatment. A technique for producing high-strength aluminum alloys, which consists in obtaining ring blanks by means of direct crystallization of melts with application of non-stationary centrifugal force fields and simultaneous introduction of modifiers, is proposed. The microstructure and plasticity of resulting tube-shaped blanks allow them to be exposed to sheeting for subsequent production of pipe workpieces with mechanical strength commensurate with mechanical strength of structural steel. The technique involves hydrothermal synthesis of nanostructured particles of aluminum oxide, which are overheated above the melt temperature prior to introduction into the molten aluminum alloy. This procedure enhances the processes of intercrystalline hardening with minimal fluctuations of internal stresses within the hardened material. The materials have tensile strength of up to 380 MPa (before modification by nanodispersed aluminum oxide it was 210 MPa). The microstructure has showed changes in the acicular dendrite component, which tends to become more dispersed and equiaxial. Eventually this leads to an increase in the mechanical strength by a factor of 1.25–1.32. Традиционные марки алюминиевых сплавов не всегда могут обеспечить выполнение требований современной ракетно-космической и авиационной техники. Литейные сплавы системы Al–Si из-за структурных особенностей – грубых хрупких включений кремния и интерметаллических фаз, имеют невысокий уровень прочностных свойств и низкую пластичность, не позволяющую проводить их обработку давлением. Предложена технология создания высокопрочных алюминиевых сплавов, заключающаяся в получении кольцевых заготовок методом направленной кристаллизации расплава при наложении нестационарных силовых полей центробежных сил и одновременном введении модификаторов. Полученные заготовки имеют микроструктуру и пластичность, позволяющую подвергать их раскатке, и форму трубных заготовок, механическая прочность которых соизмерима с конструкционной сталью. Технология включает в себя гидротермальный синтез наноструктурированных частиц оксида алюминия, которые перед введением в расплав алюминиевого сплава перегреваются выше температуры расплава, что повышает полноту протекания процессов интеркристаллического упрочнения при минимальных колебаниях по объему упрочненного материала внутренних напряжений. Материалы имеют предел прочности до 380 МПа (до модификации нанодисперсным оксидом алюминия – 210 МПа). В микроструктуре наблюдается изменение игольчатой дендритной составляющей, которая становится более дисперсной и равноосной, что и приводит к повышению механической прочности в 1,25–1,32 раза.
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
Mutations in the genes encoding isocitrate dehydrogenase, IDH1 and IDH2, have been reported in gliomas, myeloid leukemias, chondrosarcomas, and thyroid cancer. We discovered IDH1 and IDH2 mutations in 34 of 326 (10%) intrahepatic cholangiocarcinomas. Tumor with mutations in IDH1 or IDH2 had lower 5-hydroxymethylcytosine (5hmC) and higher 5-methylcytosine (5mC) levels, as well as increased dimethylation of histone H3K79. Mutations in IDH1 or IDH2 were associated with longer overall survival (p = 0.028) and were independently associated with a longer time to tumor recurrence after intrahepatic cholangiocarcinoma resection in multivariate analysis (p = 0.021). IDH1 and IDH2 mutations are significantly associated with increased levels of p53 in intrahepatic cholangiocarcinomas, but no mutations in the p53 gene were found, suggesting that mutations in IDH1 and IDH2 may cause a stress that leads to p53 activation. We identified 2,309 genes that were significantly hypermethylated in 19 cholangiocarcinomas with mutations in IDH1 or IDH2, compared with cholangiocarcinomas without these mutations. Hypermethylated CpG sites were significantly enriched in CpG shores and upstream of transcription start sites, suggesting a global regulation of transcriptional potential. Half of the hypermethylated genes overlapped with DNA hypermethylation in IDH1-mutant gliobastomas, suggesting the existence of a common set of genes whose expression may be affected by mutations in IDH1 or IDH2 in different types of tumors
Cassini Radio Science
Cassini radio science investigations will be conducted both during the cruise (gravitational wave and conjunction experiments) and the Saturnian tour of the mission (atmospheric and ionospheric occultations, ring occultations, determinations of masses and gravity fields). New technologies in the construction of the instrument, which consists of a portion on-board the spacecraft and another portion on the ground, including the use of the Ka-band signal in addition to that of the S- and X-bands, open opportunities for important discoveries in each of the above scientific areas, due to increased accuracy, resolution, sensitivity, and dynamic range.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/43765/1/11214_2004_Article_1436.pd
DETERMINATION OF CONTACT WETTING ANGLE ON FLAT SURFACES
The paper considers an improved technique for determination of a contact wetting angle. Description of the devices that make it possible to determine a contact wetting angle with due account of surface roughness is given in the paper. A specified formula for calculation of a contact wetting angle has been derived
BEHAVIOR OF MINERALS IN AGRO SODDY PODZOLIC SOILS RESULTED FROM DIFFERENT RATES OF ORGANIC FERTILIZERS
The experimental results showed the impact rendered by different rates of organic fertilizers in the kind of poultry excrements on crystallochemical parameters of minerals containing in the fine-dispersed fractions (less than 1, 1-5, 5-10 mkm). The considerable changes induced by increased rates of organic fertilizers take place in the ratio between the basic mineral phases and the crystallochemistry of minerals of the clay fraction as the most functional part of soil. One should indicate that the content of the clay fraction decreases, the layered silicates are destroyed and transformed as affected by higher rates of potassium and ammonium, fixed by mixed-layered formations with smectite pockets. The functionally inert minerals such as quartz, feldspar, plagi-oclase and mica of dioctahedral type are accumulated
Calculation Variant of Economic Efficiency in the Process of Mastering New Technique, Technology and Equipment
The paper gives a variant of determination of economic efficiency while using new technique, technology and equipment under conditions of market economy. The calculation has been made for technological processes of machining steel, cast iron and aluminium alloy cases of automobile brake cylinders
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