Do Surgeons Anticipate Women’s Hopes and Fears Associated with Prolapse Repair? A Qualitative Analysis in the PROSPERE Trial

Women’s preoperative perceptions of pelvic-floor disorders may differ from those of their physicians. Our objective was to specify women’s hopes and fears before cystocele repair, and to compare them to those that surgeons anticipate. We performed a secondary qualitative analysis of data from the PROSPERE trial. Among the 265 women included, 98% reported at least one hope and 86% one fear before surgery. Sixteen surgeons also completed the free expectations-questionnaire as a typical patient would. Women’s hopes covered seven themes, and women’s fears eleven. Women’s hopes were concerning prolapse repair (60%), improvement of urinary function (39%), capacity for physical activities (28%), sexual function (27%), well-being (25%), and end of pain or heaviness (19%). Women’s fears were concerning prolapse relapse (38%), perioperative concerns (28%), urinary disorders (26%), pain (19%), sexual problems (10%), and physical impairment (6%). Surgeons anticipated typical hopes and fears which were very similar to those the majority of women reported. However, only 60% of the women reported prolapse repair as an expectation. Women’s expectations appear reasonable and consistent with the scientific literature on the improvement and the risk of relapse or complication related to cystocele repair. Our analysis encourages surgeons to consider individual woman’s expectations before pelvic-floor repair

Place de l'IRM pelvienne dynamique dans la prise en charge chirurgicale du prolapsus génital

STRASBOURG-Medecine (674822101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Rétention chronique d'urine non obstructive et hyperactivité vésicale idiopathique réfractaires aux traitements médicamenteux (résultats de la neuromodulation sacrée et expérience de la toxine botulique en 3ème ligne thérapeutique)

STRASBOURG-Medecine (674822101) / SudocSudocFranceF

Le sphincter artificiel urinaire chez l'homme et la femme (indications, resultats et complications.)

STRASBOURG-Medecine (674822101) / SudocPARIS-BIUM (751062103) / SudocSudocFranceF

Chromium catalyzed ethylene oligomerization – new ligands and mechanistic insights (affiche)

communication par afficheCatalyzed selective ethylene oligomerization for the production of short-chain linear α-olefins (LAOs) is a subject of paramount interest both from a industrial and academic viewpoint due to the importance of LAOs as feedstock in a great variety of processes ranging from copolymerization to the fabrication of detergents and plasticizer alcohols, only to name a few. Catalyst precursors comprising a chromium metal center and chelating bisphosphine ligands figure amongst the most efficient systems for the selective tri- and tetramerization of ethylene. P^N^P type ligands were synthesized in a Mannich-type reaction, and coordinated to chromium (III), affording novel octahedral complexes, which proved to be active in the oligomerization of ethylene upon activation with methylaluminoxane. It is demonstrated, that the coordination mode to the metal center, the basicity and the steric bulk of the ligand determine the selectivity of the catalyst towards the formation of a particular oligomer chain length. The experimental findings are rationalized by DFT calculations on the metalacyclic mechanism of the oligomerization reaction. It will be shown that in the case of the P^N^P ligand, growth of the metalacycle beyond a seven-membered ring is hindered depending on the steric bulk of the ligand and thus responsible for the selectivity towards 1-hexene, or inversely, the formation of 1-octene becomes possible