6 research outputs found

    優れたヒストン脱アセチル化酵素阻害剤であるFR901228は,難治性膵癌細胞株においてcell cycle arrestに引き続きapoptosisを誘導する

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    取得学位 : 博士(医学), 学位授与番号 : 医博甲第1635号 , 学位授与年月日 : 平成16年6月30日, 学位授与大学 : 金沢大

    Xanthogranulomatous cholecystitis mimicking gallbladder carcinoma with a false-positive result on fluorodeoxyglucose PET

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    Recently, several reports have demonstrated that fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) is useful in differentiating between benign and malignant lesions in the gallbladder. However, there is a limitation in the ability of FDG-PET to differentiate between inflammatory and malignant lesions. We herein present a case of xanthogranulomatous cholecystitis misdiagnosed as gallbladder carcinoma by ultrasonography and computed tomography. FDG-PET also showed increased activity. In this case, FDG-PET findings resulted in a false-positive for the diagnosis of gallbladder carcinoma

    内視鏡を用いたomental patch method にて胃管を温存し救命しえた胸腔鏡下食道切除後胃管穿孔の1例

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    金沢大学附属病院肝胆膵・移植外科患者は70 歳,男性.腹部食道癌に対して胸腔鏡下食道亜全摘,胸骨後胃管再建,頸部吻合を施行した.第2 病日に右胸腔ドレーンより腸液色の排液を認め,CT,上部消化管透視にて胃管穿孔と診断し,再手術を行った.頸部吻合より肛門側約10 cm に胃管穿孔を認めた.胃管切除は手術侵襲が大きいと判断し,消化管内視鏡の先端を穿孔部へ通し,把持鉗子を腹腔内に進め,大網を把持して胃管内まで吊上げ,クリップにて胃壁に固定した.再手術後,ドレーン排液量は漸減し,穿孔部は再生組織に覆われた.食道癌術後胃管穿孔に対して胃管切除が選択できない場合,穿孔部の大網被覆と穿孔部周囲のドレナージは有効な場合もあると考えられたため,若干の考察を加えて報告する.A 70 -year-old man underwent retrosternal gastric tube reconstruction following subtotal esophagectomyfor advanced abdominal esophageal cancer. On the second post-operative day, drained fluid changed to intestinaljuice. Computed tomography and gastrointestinal fluoroscopy showed perforation of the gastric tube. Wethen performed emergency surgery, and laparotomy was redone. During surgery, gastrointestinal endoscopydemonstrated gastric tube perforation at 10 cm from the anastomosis of stomach to cervical esophagus. Itwas too invasive to perform the resection of gastric tube, so we pulled the greater omentum into the stomachthrough the perforation site and fastened with clips( omental patch method). The drainage then graduallydecreased, and the perforation healed with regenerating epithelium. The omental patch method and drainageproved useful to treat gastric tube perforation following esophagectomy, and should be considered if resectionof the gastric tube is difficult
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