Intervention program to promote self-management for prevention of lymphedema after gynecological cancer surgery ― Evaluation of the effectiveness at 12 months after the intervention –

In Japan cancer has been the most common cause of deaths since 1981, and effort has been made to provide countermeasure for cancers. The key to countermeasures is for the general population including cancer patients to know about and overcome cancer. Because the development of cancer is related to lifestyle, it is necessary to work at preventing cancer with attention to the conduct of daily life. The five-year relative survival rate registered in the community from 2006 to 2008 was 62.1%, and this illustrates that there are many cancer survivors leading daily lives after contracting cancer. Uterine cancer was the fifth most common in cancer in 2013. However, it is an important object of the treatment to prevent postoperative complications in gynecologic cancer patients, such as development of lymphedema, because it is reported that the survival rate of uterine cancer is high. The incidence of lymphedema is reported to be between 27.2% and 42% in Japan. Once lymphedema develops, it is difficult to cure, making prevention of the onset an important issue.As a result of the multiple logistic regression analysis performed here using patients where the right femoral circumference increased 2 cm or more as an objective variable, there were differences between the groups analyzed (intervention and control). Compared to the intervention group, 4.46 times more patients in the control group had increases in the right femoral circumference by 2 cm or more. We conducted a randomized controlled trial of an intervention program to promote self-management to prevent lymphedema development after gynecological cancer surgery, and examined the effectiveness at 12 months after the surgery. From the results it can be inferred that observing the lymphedema symptoms including measuring and recording of femoral circumferences and body weight by patients themselves influenced the promotion of self-management. Six months after the surgery, there were significantly more patients who developed lymphedema in the control group, but there were no differences between the groups at 12 months after the surgery. Lymphedema development after gynecological cancer surgery appears about 2.6 months after surgery and chronic lymphedema often appears around 9.7 months after surgery. It can be inferred that this difference is due to the temporary improvement of lymphatic reflux after the improvement of edema. The difference in femoral circumferences is sometimes used as one diagnostic tool for the determination of lymphedema. In this study, we compared the right femoral circumferences before discharge and 12 months after the surgery. Mild lymphedema is defined as larger than 10 mm but smaller than 20 mm in any dimension. In severe cases, a dimension may be larger than 20 mm]. In this study, we performed a multiple logistic regression analysis by defining the patients with lymphedema as patients whose right femoral circumference is increased more than 2 cm. The analysis showed the following as factors influencing the increase in the right femoral circumference by more than 2 cm: group (intervention and control), aerobic exercise, and self-efficacy. Compared to the intervention group, 4.46 times more patients in the control group had increases in the right femoral circumference of more than 2 cm, and this suggests that the intervention program to promote self-management to prevent lymphedema after gynecological cancer surgery is effective at 12 months after the surgery

The Effect of Brushing by a Human on Behavioral and Physiological Stress Indicators of Cows (Advanced Studies on Sustainable Animal Production: Interrelationships among Human, Animal and Environment, 8th International Symposium of Integrated Field Science)

Poster Sessio

Enhancement of norepinephrine-induced transient contraction in aortic smooth muscle of diabetic mice.

Changes in norepinephrine-induced transient contractions in Ca2+-deficient solution were investigated in the aortic smooth muscles of diabetic ALS (alloxan-induced diabetes susceptible) mice. The transient contractions in diabetic mice were significantly larger than those in normal mice. The longer incubation of the muscle preparations in Ca2+-deficient solution made the transient contractions smaller, probably due to the leakage and decrease in norepinephrine-releasable stored Ca2+. The rate of this reduction in contraction was slower in diabetic mice. These results suggest that the leakage of intracellular stored Ca2+ caused by extracellular Ca2+ deficiency is attenuated in diabetic mice, contributing to enhanced norepinephrine-induced transient contractions.</p

Localizing Japanese toads in a mountainous terrain using drone-based radiotelemetry

山に棲む小動物の位置を空から推定する --生物に装着した電波発信機をドローンで捜索--. 京都大学プレスリリース. 2023-06-09.Monitoring the movement of small animals is a fundamental aspect of ecological studies as well as spatially explicit conservation and management. However, this remains a challenging task especially in mountainous terrains. Although drone-based radiotelemetry (DRT) is employed to localize animals, its application in mountainous terrains is limited by the collision risks associated with undulating terrains as well as the obstruction of signals by dense vegetation and steep slopes. We addressed these challenges by generating fine-scale three-dimensional maps and moving vertically mounted directional antennas in a double grid pattern, scanning both in longitudinal and latitudinal grids. This new DRT system was helpful in localizing four adult Japanese toads (Bufo japonicus) living in hiding places typical of mountainous terrains. All toads were located within 1–60 days of being released. Transmitter signals were detected within two consecutive flights (three flights in one case). Instances of transmitter detection were significantly biased when the drone was facing either direction of the double-grid path, indicating that the double-grid pattern had reduced detection failure. The absolute localization error (n = 48) of 22.4 ± 21.0 m (44.8 ± 42% of the transmitter-to-receiver distance) was lower than that reported in a previous study conducted in a similar mountainous terrain

Causal Model of Work Engagement among Registered Nurses and Licensed Practical Nurses Working in Long-Term Care Contexts in Japan

The objective of this study was to determine a causal process underlying work engagement, in which individual resources (i.e., resilience) and job resources influence work performance, mediated by work engagement in different types of nurses working in long-term care contexts. We investigated a work engagement causal model in which individual and job resources were set as antecedent factors, work engagement as a mediating factor, and work performance as the outcome, to clarify differences between registered nurses (RNs) and licensed practical nurses (LPNs) working in long-term care contexts. We conducted a questionnaire-based survey with 1,786 Japanese nurses working in long-term care contexts in the Tohoku region. Using 1,269 respondents, we examined the causal model using structural equation modeling (SEM) and multiple population analysis to compare between RNs and LPNs. The results revealed a process whereby individual and job resources influenced work performance, mediated by work engagement, in RNs. In other words, greater individual and job resources enhance pride in work and positive emotion (i.e., work engagement), and greater positive emotion improves work performance. This process was not equivalent in LPNs. In LPNs, the most significant factor affecting work performance was the direct effect of job resources; moreover, the mediating effect of work engagement was not supported. The results demonstrated that in order to improve performance among LPNs working in long-term care contexts, it is important to provide job resource support, as well as to facilitate positive emotion through pride in one’s work

The validity of Salivary-amylase as Stress Marker of Cattle (Advanced Studies on Sustainable Animal Production: Interrelationships among Human, Animal and Environment, 8th International Symposium of Integrated Field Science)

Poster Sessio

The use of thermally expandable microcapsules for increasing the toughness and heal structural adhesives

In this research, the effect of thermally expandable microcapsules (TEMs) on mode I fracture toughness of structural adhesives were investigated. The single-edge-notch bending (SENB) test was used. Firstly, a standard toughness test was performed on adhesives with microcapsules. Secondly, since TEMs start their expansion at approximately 60ºC, the next specimens were fatigue tested expecting a local heating in the notch leading to the desired expansion before being statically loaded for fracture toughness determination. Thirdly, a manual local heating at 90ºC was applied in the notch before the fracture static test. The experimental results were successfully cross-checked through a numerical analysis using the virtual crack closure technique (VCCT) based on linear elastic fracture mechanics (LEFM). The major conclusion is that fracture toughness of the modified adhesives increased as the mass fraction of the TEMs increased

The use of thermally expandable microcapsules for increasing the toughness and heal structural adhesives

In this research, the effect of thermally expandable microcapsules (TEMs) on mode I fracture toughness of structural adhesives were investigated. The single-edge-notch bending (SENB) test was used. Firstly, a standard toughness test was performed on adhesives with microcapsules. Secondly, since TEMs start their expansion at approximately 60ºC, the next specimens were fatigue tested expecting a local heating in the notch leading to the desired expansion before being statically loaded for fracture toughness determination. Thirdly, a manual local heating at 90ºC was applied in the notch before the fracture static test. The experimental results were successfully cross-checked through a numerical analysis using the virtual crack closure technique (VCCT) based on linear elastic fracture mechanics (LEFM). The major conclusion is that fracture toughness of the modified adhesives increased as the mass fraction of the TEMs increased