2,204 research outputs found

    Extracting Word Sequence Correspondences with Support Vector Machines

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    method of word sequence correspondences from non-aligned parallel corpora with Support Vector Machines, which have high ability of the generalization, rarely cause over-fit for training samples and can learn dependencies of features by using a kernel function. Our method uses features for the translation model which use the translation dictionary, the number of words, part-of-speech, constituent words and neighbor words. Experiment results in which Japanese and English parallel corpora are used archived 81.1 % precision rate and 69.0 % recall rate of the extracted word sequence correspondences. This demonstrates that our method could reduce the cost for making translation dictionaries

    Secondary Prevention of Uterine Cervical Cancer

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    Secondary prevention by cervical cytology has clearly improved the mortality rate of uterine cervical cancer (CC) by enabling early detection and treatment of high-grade squamous intraepithelial lesion (HSIL) or cervical intraepithelial neoplasia (CIN), which is a precancerous lesion. In the past two decades, HPV-DNA testing, including HPV typing, has clearly brought about positive effects on secondary prevention of CC. However, in practice, CC remains a fatal disease and is the second leading cause of cancer deaths in women aged 20–39 years. Although elucidation of the mechanisms of HPV carcinogenesis and development of a prophylactic vaccine have made CC a preventable disease, eradication of CC is expected to take several decades. Therefore, primary screening to decrease the mortality rate of CC will remain important for a while. In addition, the clinical application of simple biomarkers to stratify HPV-positive women is important for maintenance of medical economy and avoidance of overtreatment in women in the reproductive age. Therefore, the development of an inexpensive therapy or vaccine that can be used worldwide is necessary to overcome cancer deaths due to CC

    DNA Repair and Chemotherapy

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    Quantum Critical Point of Itinerant Antiferromagnet in the Heavy Fermion Ce(Ru_{1-x}Rh_x)_2Si_2

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    A focus of recent experimental and theoretical studies on heavy fermion systems close to antiferromagnetic (AFM) quantum critical points (QCP) is directed toward revealing the nature of the fixed point, i.e., whether it is an itinerant antiferromagnet [spin density wave (SDW)] type or a locally-critical fixed point. The relevance of the local QCP was proposed to explain the E/T-scaling with an anomalous exponent observed for the AFM QCP of CeCu_{5.9}Au_{0.1}. In this work, we have investigated an AFM QCP of another archetypal heavy fermion system Ce(Ru_{1-x}Rh_x)_2Si_2 with x = 0 and 0.03 (sim x_c) using single-crystalline neutron scattering. Accurate measurements of the dynamical susceptibility Im[chi(Q,E)] at the AFM wave vector Q = 0.35 c^* have shown that Im[chi(Q,E)] is well described by a Lorentzian and its energy width Gamma(Q), i.e., the inverse correlation time depends on temperature as Gamma(Q) = c_1 + c_2 T^{3/2 +- 0.1}, where c_1 and c_2 are x dependent constants, in low temperature ranges.This critical exponent 3/2 proves that the QCP is controlled by the SDW QCP in three space dimensions studied by the renormalization group and self-consistent renormalization theories.Comment: 4 pages, 4 figures, LT24 (Aug. 2005, Orlando

    A Prospective Study of Long-term Outcomes in Female Patients with Nonalcoholic Steatohepatitis Using Age- and Body Mass Index-matched Cohorts

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    In patients with nonalcoholic steatohepatitis (NASH), the prevalence of cirrhosis is higher among women than men, and hepatocellular carcinoma (HCC) develops mainly in the cirrhotic stage among women. However, the long-term outcomes in female patients with NASH have not been fully elucidated, and age, gender and BMI were not simultaneously adjusted in previous studies on the prognosis of NASH. To elucidate the outcomes in female patients with NASH, we prospectively compared NASH patients with advanced fibrosis (advanced NASH) with hepatitis C virus-related advanced fibrosis (advanced CHC) patients and NASH patients with mild fibrosis (mild NASH) using study cohorts that were adjusted for body mass index (BMI) in addition to age. The median follow-up period was 92.5 months. Liver-related complication-free survival was significantly reduced in the advanced NASH group compared to the mild NASH group. No liver-related complications developed in the mild NASH group. The overall survival, liver-related complication- and cardiovascular/cerebrovascular disease-free survival were not significantly different between the advanced NASH and CHC groups. Female patients with NASH and advanced fibrosis may have a less favorable prognosis for liver-related complications than the matched cohorts with NASH and mild fibrosis, but may have a similar prognosis to the matched cohorts with CHC

    Self-generation of hollow current profile and tilt instability in field-reversed configuration

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    Two-dimensional electromagnetic particle simulation is performed to investigate the profile relaxation from a magnetohydrodynamic (MHD) equilibrium to a kinetic one and the physical property of the kinetic equilibrium in the field-reversed configuration. The radial oscillation is excited in order to relax an excess energy in the MHD equilibrium. After this profile oscillation, the system spontaneously relaxes toward a kinetic equilibrium, in which the electron current profile becomes hollow as a result of the combined effects of the gradient-B drift near the field-null line and the E×B drift generated by the ion finite Larmor radius effect near the magnetic separatrix. On the other hand, the ion current profile becomes peaked due to the effect of the ion meandering orbit near the field-null line. The stability of the obtained kinetic equilibrium against the tilt mode is also studied by means of three-dimensional full electromagnetic particle simulation. It is found that the growth rate of the tilt instability in the case of the hollow current profile and high separatrix beta value is smaller than that in the case of the peaked current profile
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