29 research outputs found
Synthesis of a potential steroid intermediate by anionic oxy-cope rearrangement
The synthesis of the tricyclic ketol 6̲ which is a potential intermediate for non-aromatic steroids has been achieved via an anionic oxy-Cope rearrangement
A new synthesis of angularly substituted bicyclic systems via an anionic oxy-cope rearrangement
A general synthesis of trans bicyclic carbinols with an angular methyl substituent using the anionic oxy-Cope rearrangement is reported. The carbinols 13a̲ ,13b̲ ,14a̲ ,14b̲ and 15̲ furnish the bicyclic carbinols 16a̲, 16b̲, 17a̲, 17b̲ and 18̲ when treated with potassium hydride in 1,2-dimethoxyethane