Salivary glucose estimation: A noninvasive method

Background: There is an alarming rise in number of people with diabetes mellitus over these years. Oral physicians are more liable to come in contact with a significant number of patients with diabetes mellitus. Due to the lack of early diagnosis and treatment, diabetes is a major cause of death worldwide. While the early diagnosis of diabetes is essential to prevent its complication, the most commonly used diagnostic method is by the detection of glucose level in blood, but the sample collection is invasive and painful. Thus, there arises a need for a noninvasive and painless technique to detect glucose levels. The aim of this study is to estimate the glucose levels in saliva and correlate it with serum glucose. Materials and Methods: The study was conducted in the Outpatient Department of Oral Medicine and Radiology. Forty patients' serum and saliva were collected and the levels were estimated using the glucose oxidase-peroxidasemethod. Results: Data obtained was subjected to statistical analysis using t-test. Highly significant P value (P = 0.00) was obtained between the serum blood glucose and salivary glucose level. A distinct difference was observed in the salivary glucose between the control and diabetic group. Conclusion: Diabetes mellitus is a globally widespread disease. As the salivary collection is easy and noninvasive, in this study, an attempt has been made to diagnose diabetes mellitus by estimating the salivary glucose level in comparison with serum blood glucose level

A Review of Oral Candidiasis in Oral Mucosal Lesions

ABSTRACT Oral candidiasis is the most common fungal infection encountered in general dental practice. The ability of the Candida species to colonize surfaces can be considered as a risk factor for oral infection. There are a number of oral lesions that are clearly associated, more often than others, with either candidial infestation or frank invasion. This article reviews about Oral candidiasis in Oral mucosal infections

Role of Nanotechnology in Cancer Therapy

ABSTRACT Oral cancer is a deadly and disfiguring disease that could greatly benefit from new diagnostic approaches enabling early detection. Nanoparticulate technology is of particular use in developing a new generation of more effective cancer therapies capable of overcoming the many biological, biophysical, and biomedical barriers that the body stages against a standard intervention. Nanoparticles show much promise in cancer therapy by selectively gaining access to tumor due to their small size and modifiability. In cancer treatment and detection nanoparticles serve many targeted functions in chemotherapy, radiotherapy, immunotherapy, photodynamic therapy, imaging and Nanoparticulate Targeting. This article is an overview of advances and prospects in the applications of nanocarrier technology in cancer therapy

Radiation Protection in Dental Radiology- The Safe Use of Radiographs in Dental Practice

Radiographs have been widely used in dentistry for various reasons such as diagnosis, treatment planning, during the treatment procedures and assessment of treatment outcome. In our routine dental practice dentists practice intraoral radiography in their clinics. The radiograph when made immediately in the dental chair is a real-time diagnostic aid but the dentist should also confirm whether he/she follows all the guidelines and safety precautions of radiation safety while exposing the patient to X-rays so that the deleterious effects of X-rays can be avoided which will be beneficial to both the patient and especially the dentists who have long term exposure to X-rays. Hence in this article we have emphasized on the safety precautions to be followed by the dentists and also the awareness each of us should possess towards the hazards of radiation