8 research outputs found

    The role of signal transducer and activator of transcription-3 (STAT-3) in ischaemic and pharmacological postconditioning

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    Includes abstract. Includes bibliographical references (leaves 131-147)

    Role of nuclear factors kappa-B in TNFα-induced cytoprotection

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    Includes bibliographical references (leaves 67-81)

    Interplay between SAFE and RISK pathways in sphingosine-1-phosphate-induced cardioprotection

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    We studied the role of two powerful molecular signalling mechanisms involved in the cardioprotective effect of sphingosine-1-phosphate (S1P), a major component of high density lipoprotein (HDL) against myocardial ischaemic-reperfusion injury, namely the RISK pathway (Akt/Erk), including its downstream target FOXO-1 and, the SAFE pathway (TNF/STAT-3)

    Pressuromodulation at the cell membrane as the basis for small molecule hormone and peptide regulation of cellular and nuclear function

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    Progression of Geographic Atrophy in Age-related Macular Degeneration

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    Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials

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