Computer-Aided Designed/Computer-Aided Manufactured and Conventional Techniques in Maxillofacial Reconstruction with Free Fibula Flaps

We treated 26 patients via vascularized osteocutaneous fibula flaps for maxillofacial osseous reconstruction between September 2012 and October 2015. The CAD/CAM technique was attempted for all patients needing bony maxillofacial reconstructions. The time interval from deciding to use the CAD/CAM technique and receiving the hardware depended on the capacity of the CAD/CAM providing companies. It usually takes between 3 and 4 weeks. Hence, the CAD/CAM technique was not used for patients with rapid tumor growth or pathologic fractures of the mandible. In these urgent cases, surgery could not be delayed and the conventional technique was used. In the abovementioned time period, 11 patients underwent osseous reconstruction using CAD/CAM and 15 patients using the conventional technique. Data were collected and evaluated according to demographics, medical history, number of bone segments, and complications. Time measurements of virtual planning sessions, flap harvesting, flap ischemia, tourniquet inflation, total reconstruction, and overall operating times were additionally recorded

Determination of Serum Adenosine Deaminase and Xanthine Oxidase Levels in Patients with Crimean–Congo Hemorrhagic Fever

OBJECTIVE: Crimean-Congo hemorrhagic fever is an acute viral hemorrhagic fever with a high mortality rate. Despite increasing knowledge about hemorrhagic fever viruses, little is known about the pathogenesis of Crimean-Congo hemorrhagic fever. In this study, we measured serum adenosine deaminase and xanthine oxidase levels in Crimean-Congo hemorrhagic fever patients. METHODS: Serum adenosine deaminase levels were measured with a sensitive colorimetric method described by Giusti and xanthine oxidase levels by the method of Worthington in 30 consecutive hospitalized patients (mean age 42.6 ± 21.0). Laboratory tests confirmed their diagnoses of Crimean-Congo hemorrhagic fever. Thirty-five subjects (mean age 42.9 ± 19.1) served as the control group. RESULTS: There was a significant difference in adenosine deaminase and xanthine oxidase levels between cases and controls (p<0.05). However, neither adenosine deaminase nor xanthine oxidase levels varied with the severity of disease in the cases assessed (p>0.05). CONCLUSION: Adenosine deaminase and xanthine oxidase levels were increased in patients with Crimean-Congo hemorrhagic fever. Elevated serum xanthine oxidase activity in patients with Crimean-Congo hemorrhagic fever may be associated with reactive oxygen species generated by the xanthine/xanthine oxidase system during inflammatory responses. In addition, elevated lipid peroxidation may contribute to cell damage and hemorrhage. The association of cell damage and hemorrhage with xanthine oxidase activity should be further investigated in large-scale studies

Two new 3-benzylphthalides from Scorzonera veratrifolia Fenzl

A phytochemical investigation of Scorzonera veratrifolia Fenzl (Asteraceae) yielded two new 3-benzylphthalides, scorzoveratrin (1) and scorzoveratrozit (2), together with five known compounds, chlorogenic acid (3), chlorogenic acid methyl ester (4), cryptochlorogenic acid (5), 4,5-dicaffeoylquinic acid (6) and 3,5-dicaffeoylquinic acid (7). All secondary metabolites were assigned using physicochemical and spectroscopic data. The known compounds 3-7 were isolated for the first time from this species

Phenolic compounds from Scorzonera latifolia (Fisch & Mey.) DC

A new 3-benzylphthalide, scorzoveratrin 4'-O-beta-glucoside (1), together with the known 3-benzylphthalides, scorzoveratrin (2) and scorzoveratrozit (3), the caffeoyl derivatives, chlorogenic acid methyl ester (4), 4,5-dicaffeoylquinic acid (5), 4,5-dicaffeoylquinic acid methyl ester (6), 3,5-dicaffeoylquinic acid (7) and caffeic acid (8) were isolated from the subaerial parts of Scorzonera latifolia (Fisch. & Mey.) DC. All secondary metabolites were assigned using physicochemical and spectroscopic data. The known compounds 2-8 were isolated for the first time from this species

Plants used in traditional treatment against diarrhea in Turkey

WOS: 000466961800006Turkey is one of the richest countries in the world in terms of flora with its extraordinary plant diversity. Its flora consists of about 10,000 vascular plants and approximately one third of them (34.4 %) are endemic to the country. In recent years, the use of ethnobotanical information obtained from medicinal plant research has gained attention all around the world. For this reason, numerous ethnobotanical studies have recently been published and much has been written about medicinal plants in our country. This study deals with 133 taxa used in traditional treatments against diarrhea in Turkey and it aims to give information about scientific and local names of these taxa, families, used parts and usage in diarrhea