The Need for Evidence-Based Interventions to Reduce Food Insecurity Among College Students

Food insecurity is defined as insufficient resources to meet food needs. This is a global problem but is not confined to those countries identified as poor. One group of Americans who are particularly affected, and for whom the effects are particularly severe, is college students

Inside Look: Digitizing a Historic Card Index

Oregon Index Online (https://digital.osl.state.or.us/islandora/object/osl:or_index) is a resource for discovering information about the news, events, and people who shaped Oregon. It builds on the decades of work that went into creating the physical Oregon Index. This article reviews the methods library staff took to digitize and process nearly 800,000 cards to make the Oregon Index available online.   Note: A new version of this article was posted on Nov. 6, 2020, to include the authors' updated State Library of Oregon email addresses

A Comparison of Oral and Intravenous Mouse Models of Listeriosis

Listeria monocytogenes is one of several enteric microbes that is acquired orally, invades the gastric mucosa, and then disseminates to peripheral tissues to cause systemic disease in humans. Intravenous (i.v.) inoculation of mice with L. monocytogenes has been the most widely-used small animal model of listeriosis over the past few decades. The infection is highly reproducible and has been invaluable in deciphering mechanisms of adaptive immunity in vivo, particularly CD8+ T cell responses to intracellular pathogens. However, the i.v. model completely bypasses the gut phase of the infection. Recent advances in generating both humanized mice and murinized bacteria, as well as the development of a foodborne route of transmission has reignited interest in studying oral models of listeriosis. In this review, we analyze previously published reports to highlight both the similarities and differences in tissue colonization and host response to infection using either oral or i.v. inoculation

Regular ideals, ideal intersections, and quotients

Let $B \subseteq A$ be an inclusion of C$^*$-algebras. We study the relationship between the regular ideals of $B$ and regular ideals of $A$. We show that if $B \subseteq A$ is a regular C$^*$-inclusion and there is a faithful invariant conditional expectation from $A$ onto $B$, then there is an isomorphism between the lattice of regular ideals of $A$ and invariant regular ideals of $B$. We study properties of inclusions preserved under quotients by regular ideals. This includes showing that if $D \subseteq A$ is a Cartan inclusion and $J$ is a regular ideal in $A$, then $D/(J\cap D)$ is a Cartan subalgebra of $A/J$. We provide a description of regular ideals in reduced crossed products $A \rtimes_r \Gamma$.Comment: 26 pages. Major revision on earlier version of the pape

“Putting on our people lens”: Lived Experience as Pedagogy

In the professional education of mental health practitioners, including occupational therapists, there has been a lack of meaningful inclusion of people labeled with mental illness into curricula, beyond guest speaker panels and presentations. This study explored the experiences of students, faculty, and ‘Experts by Experience’ within a mental health occupational therapy course that incorporated Experts with lived experience as co-facilitators of weekly fieldwork debriefs. The study utilized focus groups and interviews to understand the experiences of students, mental health faculty, and ‘Experts by Experience’. Key themes that emerged from the qualitative data analysis were organized under three broad categories: 1) Students experienced powerful insights, 2) Experts conveyed the complexity of the work, and 3) Faculty grew from co-creating learning experiences with the Experts. This research makes a significant contribution to occupational therapy education by shifting the Expert’s role beyond traditional speaker panels or storytelling. This broader responsibility elevated experiential knowledge into the realm of practice in clinical reasoning by shifting the context of the knowledge from storytelling to support practice reasoning. While this created significant learning opportunities for the students, it also did appear to cause emotional risk for the ‘Experts by Experience’. It is important that efforts to include ‘Experts by Experience’ in curriculum also include sources of support and financial remuneration

High-Density Targeting of a Viral Multifunctional Nanoplatform to a Pathogenic, Biofilm-Forming Bacterium

SummaryNanomedicine directed at diagnosis and treatment of infections can benefit from innovations that have substantially increased the variety of available multifunctional nanoplatforms. Here, we targeted a spherical, icosahedral viral nanoplatform to a pathogenic, biofilm-forming bacterium, Staphylococcus aureus. Density of binding mediated through specific protein-ligand interactions exceeded the density expected for a planar, hexagonally close-packed array. A multifunctionalized viral protein cage was used to load imaging agents (fluorophore and MRI contrast agent) onto cells. The fluorescence-imaging capability allowed for direct observation of penetration of the nanoplatform into an S. aureus biofilm. These results demonstrate that multifunctional nanoplatforms based on protein cage architectures have significant potential as tools for both diagnosis and targeted treatment of recalcitrant bacterial infections