28,430 research outputs found

    How Students Are Making It: Perspectives on Getting Through College From Recent Graduates of the Boston Public Schools

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    Analyzes public high school graduates' college experiences by level of academic success, including the role of self-management skills, academic advising, and contextual issues related to family, employment, and financial pressures. Makes recommendations

    From EMT to HSC to AML: ZEB2 is a cell fate switch.

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    In this issue of Blood, complimentary studies by J. Li et al1 and H. Li et al2 identify the transcription factor ZEB2 as a critical regulator of multilineage differentiation in both normal and malignant hematopoiesis. In particular, these studies show that ZEB2 is an inhibitor of normal granulocyte production, and in acute myeloid leukemia (AML), antagonizing ZEB2 function releases the granulocytic differentiation block, creating an antileukemic therapeutic effect

    Tumor stiffness extends its grip on the metastatic microenvironment

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    The increased stiffness of a tumor triggers a multitude of responses that aid cancer cell dissemination. Stiffness-induced expression of CCN1 mediates autocrine signaling in the endothelium to upregulate N-Cadherin levels. This permits more stable interactions with cancer cells and increases their ability to spread into the circulation

    Applicant Attraction Strategies: An Organizational Perspective

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    Developing labor shortages are expected to increase the importance of applicant attraction into the next century. Unfonunately, previous research has provided little in the way of unified theory or operational guidelines for organizations confronted with attraction difficulties. In part, this is because much research has been framed from the applicant\u27s, rather than the organization\u27s, perspective. In addition, attraction-related theories and research are scattered across a variety of literatures, and often identified primarily with topics other than attraction per se (e.g., wage, motivation, or discrimination theories). The present paper draws on multiple literatures to develop a model of applicant attraction from the organization\u27s perspective. In it, we (1) outline three general strategies for enhancing applicant attraction, (2) propose broad categories of contingency factors expected to affect the choice (and potential effectiveness) of alternative strategies, (3) suggest probable interrelationships among the strategies, (4) link applicant attraction strategies to other human resource practices, (5) outline various dimensions of attraction outcomes (e.g. qualitative and quantitative, attitudinal and behavioral, temporal), and (6) discuss implications for future attraction research

    Who's Making It: The Academic Achievement of Recent Boston Public School Graduates in the Early College Years

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    Examines the persistence, progress, and performance of Boston public school graduates in the first two years of college; contributing factors, including academic preparation, colleges' selectivity, and full-time or part-time attendance; and implications

    Fingerprint databases for theorems

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    We discuss the advantages of searchable, collaborative, language-independent databases of mathematical results, indexed by "fingerprints" of small and canonical data. Our motivating example is Neil Sloane's massively influential On-Line Encyclopedia of Integer Sequences. We hope to encourage the greater mathematical community to search for the appropriate fingerprints within each discipline, and to compile fingerprint databases of results wherever possible. The benefits of these databases are broad - advancing the state of knowledge, enhancing experimental mathematics, enabling researchers to discover unexpected connections between areas, and even improving the refereeing process for journal publication.Comment: to appear in Notices of the AM
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