5 research outputs found
Burns Secondary to Infrared Therapy in a six year old HBSS Patient
A six-year-old male HbSS patient was referred to the physiotherapy unit of the university teaching hospital,
Ado-Ekiti. The boy had earlier presented at his regular clinic during a prolonged vaso
both lower limbs. He was treated with intramuscular (gluteal) injections alongside other management. He later
developed a left foot-drop. After a few
became scalded and sore. The other foot on which no physiotherapy was applied was normal. Case reports of
similar incidents in the literature were reviewed. Possible explanations
preventive measures suggested
Exposure to radio-frequency electromagnetic waves alters acetylcholinesterase gene expression, exploratory and motor coordinationlinked behaviour in male rats
Humans in modern society are exposed to an ever-increasing number of electromagnetic fields (EMFs) and some
studies have demonstrated that these waves can alter brain function but the mechanism still remains unclear.
Hence, this study sought to investigate the effect of 2.5 Ghz band radio-frequency electromagnetic waves (RFEMF)
exposure on cerebral cortex acetylcholinesterase (AChE) activity and their mRNA expression level as well
as locomotor function and anxiety-linked behaviour in male rats. Animals were divided into four groups namely;
group 1 was control (without exposure), group 2–4 were exposed to 2.5 Ghz radiofrequency waves from an
installed WI-FI device for a period of 4, 6 and 8 weeks respectively. The results revealed that WiFi exposure
caused a significant increase in anxiety level and affect locomotor function. Furthermore, there was a significant
decrease in AChE activity with a concomitant increase in AChE mRNA expression level in WiFi exposed rats
when compared with control. In conclusions, these data showed that long term exposure to WiFi may lead to
adverse effects such as neurodegenerative diseases as observed by a significant alteration on AChE gene expression
and some neurobehavioral parameters associated with brain damage
Exposure to radio-frequency electromagnetic waves alters acetylcholinesterase gene expression, exploratory and motor coordinationlinked behaviour in male rats
Humans in modern society are exposed to an ever-increasing number of electromagneticfields (EMFs) and some
studies have demonstrated that these waves can alter brain function but the mechanism still remains unclear.
Hence, this study sought to investigate the effect of 2.5 Ghz band radio-frequency electromagnetic waves (RFEMF) exposure on cerebral cortex acetylcholinesterase (AChE) activity and their mRNA expression level as well
as locomotor function and anxiety-linked behaviour in male rats. Animals were divided into four groups namely;
group 1 was control (without exposure), group 2–4 were exposed to 2.5 Ghz radiofrequency waves from an
installed WI-FI device for a period of 4, 6 and 8 weeks respectively. The results revealed that WiFi exposure
caused a significant increase in anxiety level and affect locomotor function. Furthermore, there was a significant
decrease in AChE activity with a concomitant increase in AChE mRNA expression level in WiFi exposed rats
when compared with control. In conclusions, these data showed that long term exposure to WiFi may lead to
adverse effects such as neurodegenerative diseases as observed by a significant alteration on AChE gene expression and some neurobehavioral parameters associated with brain damage
Immunosuppressive Acidic Protein- Haematological correlates in HIV infected subjects
Background:
Immunosuppressive Acidic protein (IAP) is a marker of the extent of
immune defects occurring in most cancers. Its correlation with CD4 cell count used as an
indicator of immune function and disease progression in Human Immuno-deficiency Virus
(HIV) infection is not well documented.
Aims and Objectives:
To determine if IAP levels
correlates with immunosupression and haematopathology occurring in HIV/AIDS infection.
Materials and Methods:
This cross sectional study was conducted at the Federal Teaching
Hospital, Ido-Ekiti. One hundred and five participants consisting of 85 HIV infected test
subjects and 20 control subjects were enrolled into the study. CD4 counts was obtained
using SL Cyflow machine, IAP levels determined using ELISA kit for human IAP and Full
blood count for all participants was obtained using Sysmex KX-21N Haematology Analyzer.
Regression and correlation analysis was done on data using SPSS 28.
Results:
IAP showed
a negative correlation with CD4 count (r=
-0.6), (r=
-0.9) and (r=
-0.2) in the ART, NART
and control groups. The pattern of the results was similar with other parameters except in
Neutrophils (r= 0.2) (r= 0.3) and (0.1), Eosinophil (r= 0.6) (r=
-0.4) and (r=
-0.2) and
Lymphocyte (r =
-0.3) (r=
-0.02) and (r= 0.05) in the ART, NART and control groups
respectively.
Conclusion:
The outcome of this study show that a strong negative relationship
exist between IAP and other immunohaematological parameters used for monitoring Immune
status in HIV infection; however the information gotten is not sufficient to indicate IAP as a
predictor of immune status in HIV infection. Further studies are therefore required to better
elucidate the mechanism of increased IAP levels at different clinical stages of HIV infection
Case Report: Burns Secondary to Infrared Therapy in a Six-year Old HBSS patient
A six-year-old male HbSS patient was referred to the physiotherapy unit of the university teaching hospital, Ado-Ekiti. The boy had earlier presented at his regular clinic during a prolonged vaso-occlusive crisis involving both lower limbs. He was treated with intramuscular (gluteal) injections alongside other management. He later developed a left foot-drop. After a few sessions of heat(infrared) therapy, the plantar surfaces of all the left toes became scalded and sore. The other foot on which no physiotherapy was applied was normal. Case reports of similar incidents in the literature were reviewed. Possible explanations of the phenomenon were advanced and preventive measures suggested. Keywords: Physiotherapy; infrared; Thermal energy; Burn