Can new generations explain neutrino masses?

In this talk we explore the possibility that the smallness of the observed neutrino masses is naturally understood in a modified version of the standard model with N extra generations of fermions and N right-handed neutrinos, in which light neutrino masses are generated at two loops. We find that with N = 1 it is not possible to fit the observed spectrum of masses and mixings while with N = 2 it is. Within this extension, we analyse the parameters which are allowed and the possible phenomenological signals of the model in future experiments. Contribution to the proceedings of Les Rencontres de Moriond EW 2011, Young Scientist Forum

Gut Microbial Antigenic Mimicry in Autoimmunity

The gut microbiota plays a major role in the developmental biology and homeostasis of cells belonging to the adaptive and innate arms of the immune system. Alterations in its composition, which are known to be regulated by both genetic and environmental factors, can either promote or suppress the pathogenic processes underlying the development of various autoimmune diseases, including inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, type 1 diabetes and rheumatoid arthritis, to just name a few. Cross-recognition of gut microbial antigens by autoreactive T cells as well as gut microbe-driven alterations in the activation and homeostasis of effector and regulatory T cells have been implicated in this process. Here, we summarize our current understanding of the positive and negative associations between alterations in the composition of the gut microbiota and the development of various autoimmune disorders, with a special emphasis on antigenic mimicry

Multiple-phase biometric relationships and sexual maturity in the atlantic bluefin tuna, thunnus thynnus (Osteichthyes: Scombridae)

Most fish undergo distinct growth phases during ontogenesis. An extremely important passage from the juvenile to adult phase occurs at the onset of sexual maturity, which shows in body proportion and/or growth rate changes. These can be detected as change-points in biometric relationships. In this paper, the Atlantic bluefin tuna was analyzed to verify whether its somatic proportions show any sign of discontinuity during growth, i.e., whether any change-points may be detected in its somatic proportions. This fish has never been examined in this respect, and single-phase models, which are indeed easier to both compute and apply, are used in stock analyses. The following somatic relationships were analyzed in Atlantic bluefin tuna captured in the Mediterranean Sea between 1998 and 2010: “fork length–weight” regression, the von Bertalanffy growth equation, and “first dorsal spine cross section surface–fork length” regression. All of the examined relationships were found to be best modelled by multiple-phase regression equations, and all of them showed a change-point within the range of 101–110 cm fork length, which corresponds to 3–4 years of age. The present results, based on reproductive state-independent analyses, corroborate the disputed hypothesis that Atlantic bluefin tuna from the eastern stock in fact reproduce for the first time at this age

Self-adaptive decision-making mechanisms to balance the execution of multiple tasks for a multi-robots team

This work addresses the coordination problem of multiple robots with the goal of finding specific hazardous targets in an unknown area and dealing with them cooperatively. The desired behaviour for the robotic system entails multiple requirements, which may also be conflicting. The paper presents the problem as a constrained bi-objective optimization problem in which mobile robots must perform two specific tasks of exploration and at same time cooperation and coordination for disarming the hazardous targets. These objectives are opposed goals, in which one may be favored, but only at the expense of the other. Therefore, a good trade-off must be found. For this purpose, a nature-inspired approach and an analytical mathematical model to solve this problem considering a single equivalent weighted objective function are presented. The results of proposed coordination model, simulated in a two dimensional terrain, are showed in order to assess the behaviour of the proposed solution to tackle this problem. We have analyzed the performance of the approach and the influence of the weights of the objective function under different conditions: static and dynamic. In this latter situation, the robots may fail under the stringent limited budget of energy or for hazardous events. The paper concludes with a critical discussion of the experimental results

High-pressure x-ray diffraction study of bulk and nanocrystalline PbMoO4

We studied the effects of high-pressure on the crystalline structure of bulk and nanocrystalline scheelite-type PbMoO4. We found that in both cases the compressibility of the materials is highly non-isotropic, being the c-axis the most compressible one. We also observed that the volume compressibility of nanocrystals becomes higher that the bulk one at 5 GPa. In addition, at 10.7(8) GPa we observed the onset of an structural phase transition in bulk PbMoO4. The high-pressure phase has a monoclinic structure similar to M-fergusonite. The transition is reversible and not volume change is detected between the low- and high-pressure phases. No additional structural changes or evidence of decomposition are found up to 21.1 GPa. In contrast nanocrystalline PbMoO4 remains in the scheelite structure at least up to 16.1 GPa. Finally, the equation of state for bulk and nanocrystalline PbMoO4 are also determined.Comment: 18 pages, 4 figure