Dust effects on the derived Sersic indexes of disks and bulges in spiral galaxies

We present a theoretical study that quantifies the effect of dust on the derived Sersic indexes of disks and bulges. The changes in the derived parameters from their intrinsic values (as seen in the absence of dust) were obtained by fitting Sersic distributions on simulated images of disks and bulges produced using radiative transfer calculations and the model of Popescu et al. 2011. We found that dust has the effect of lowering the measured Sersic index in most cases, with stronger effects for disks and bulges seen through more optically thick lines of sight.Comment: 3 pages, 2 figures, to appear in the Proceedings of the IAU Symposium No.284, "The Spectral Energy Distribution of Galaxies", 5-9 sept. 2011, editors Richard J. Tuffs and Cristina C. Popesc

Predicting the effects of sand erosion on collector surfaces in CSP plants

This paper presents a methodology to predict the optical performance and physical topography of the glass collector surfaces of any given CSP plant in the presence of sand and dust storms, providing that local climate conditions are known and representative sand and dust particles samples are available. Using existing meteorological data for a defined CSP plant in Egypt, plus sand and dust samples from two desert locations in Libya, we describe how to derive air speed, duration, and sand concentrations to use within the Global CSP Laboratory sand erosion simulation rig at Cranfield University. This then allows us to predict the optical performance of parabolic trough collector glass after an extended period by the use of accelerated ageing. However the behavior of particles in sandstorms is complex and has prompted a theoretical analysis of sand particle dynamics which is also described in this paper

The Cold and Hot Gas Content of Fine-Structure E and S0 Galaxies

We investigate trends of the cold and hot gas content of early-type galaxies with the presence of optical morphological peculiarities, as measured by the fine-structure index (Sigma). HI mapping observations from the literature are used to track the cold-gas content, and archival ROSAT PSPC data are used to quantify the hot-gas content. We find that E and S0 galaxies with a high incidence of optical peculiarities are exclusively X-ray underluminous and, therefore, deficient in hot gas. In contrast, more relaxed galaxies with little or no signs of optical peculiarities span a wide range of X-ray luminosities. That is, the X-ray excess anticorrelates with Sigma. There appears to be no similar trend of cold-gas content with either fine-structure index or X-ray content. The fact that only apparently relaxed E and S0 galaxies are strong X-ray emitters is consistent with the hypothesis that after strong disturbances such as a merger hot-gas halos build up over a time scale of several gigayears. This is consistent with the expected mass loss from stars.Comment: 12 pages, latex, 5 figures. Accepted for publication in A

Enhancing thermoelectric properties of NaCo2O4 ceramics through Na pre-treatment induced nano-decoration

High quality NaCo2O4 thermoelectrics are challenging to process due to the volatile nature of Na, the slow densification kinetics, and degradation of NaCo2O4 above 900–950 °C leading to the formation of Na-poor second phases. Fine grained sol-gel derived powders have been used to enhance the densification kinetics while pre-treatment of the NaCo2O4 powder with NaOH, to provide a Na rich environment, has been shown to mitigate Na loss at elevated temperatures. While insufficient to compensate for Na loss at processing temperatures of 1000 °C and above, at lower temperatures it is able to enhance densification and facilitate the formation of complex crystal structures yielding low thermal conductivity (0.66 Wm−1K−1) coupled with high electrical conductivity (3.8 × 103 Sm−1) and a Seebeck coefficient of 34.9. The resultant room temperature power factor and ZT were 6.19 × 10−6 Wm−1K−2 and 0.0026, respectively

Chemical enrichment of the complex hot ISM of the Antennae galaxies: I. Spatial and spectral analysis of the diffuse X-ray emission

We present an analysis of the properties of the hot interstellar medium (ISM) in the merging pair of galaxies known as The Antennae (NGC 4038/39), performed using the deep, coadded ~411 ks Chandra ACIS-S data set. These deep X-ray observations and Chandra's high angular resolution allow us to investigate the properties of the hot ISM with unprecedented spatial and spectral resolution. Through a spatially resolved spectral analysis, we find a variety of temperatures (from 0.2 to 0.7 keV) and Nh (from Galactic to 2x10^21 cm^-2). Metal abundances for Ne, Mg, Si, and Fe vary dramatically throughout the ISM from sub-solar values (~0.2) up to several times solar.Comment: 33 pages, 18 figures, revised version accepted by Astrophysical Journal Supplement Serie

Quitting patient care and career break intentions among general practitioners in South West England: findings of a census survey of general practitioners

Objective: Given recent concerns regarding general practitioner (GP) workforce capacity, we aimed to describe GPs’ career intentions, especially those which might impact on GP workforce availability over the next 5 years. Design: Census survey, conducted between April and June 2016 using postal and online responses , of all GPs on the National Health Service performers list and eligible to practise in primary care. Two reminders were used as necessary. Setting: South West England (population 3.5  million), a region with low overall socioeconomic deprivation. Participants: Eligible GPs were 2248 out of 3370 (67 % response rate). Main outcome measures: Reported likelihood of permanently leaving or reducing hours spent in direct patient care or of taking a career break within the next 5 years and present morale weighted for non-response. Results: Responders included 217 7 GPs engaged in patient care. Of these, 863 (37% weighted, 95%  CI 35 % to 39 %) reported a high likelihood of quitting direct patient care within the next 5 years. Overall, 1535 (70% weighted, 95%  CI 68 % to 72 %) respondents reported a career intention that would negatively impact GP workforce capacity over the next 5 years, through permanently leaving or reducing hours spent in direct patient care, or through taking a career break. GP age was an important predictor of career intentions; sharp increases in the proportion of GPs intending to quit patient care were evident from 52 years. Only 305 (14% weighted, 95%  CI 13 % to 16 %) reported high morale, while 1195 ( 54 % weighted, 95%  CI 52 % to 56 %) reported low morale. Low morale was particularly common among GP partners. Current morale strongly predicted GPs’ career intentions; those with very low morale were particularly likely to report intentions to quit patient care or to take a career break. Conclusions: A substantial majority of GPs in South West England report low morale. Many are considering career intentions which, if implemented, would adversely impact GP workforce capacity within a short time period. Study registration: NIHR HS&DR - 14/196/02, UKCRN ID 20700

A well-preserved ‘placoderm’ (stem-group Gnathostomata) upper jaw from the Early Devonian of Mongolia clarifies jaw evolution

The origin of jaws and teeth remains contentious in vertebrate evolution. ‘Placoderms’ (Silurian-Devonian armoured jawed fishes) are central to debates on the origins of these anatomical structures. ‘Acanthothoracids’ are generally considered the most primitive ‘placoderms’. However, they are so far known mainly from disarticulated skeletal elements that are typically incomplete. The structure of the jaws—particularly the jaw hinge—is poorly known, leaving open questions about their jaw function and comparison with other placoderms and modern gnathostomes. Here we describe a near-complete ‘acanthothoracid’ upper jaw, allowing us to reconstruct the likely orientation and angle of the bite and compare its morphology with that of other known ‘placoderm’ groups. We clarify that the bite position is located on the upper jaw cartilage rather than on the dermal cheek and thus show that there is a highly conserved bite morphology among most groups of ‘placoderms’, regardless of their overall cranial geometry. Incorporation of the dermal skeleton appears to provide a sound biomechanical basis for jaw origins. It appears that ‘acanthothoracid’ dentitions were fundamentally similar in location to that of arthrodire ‘placoderms’, rather than resembling bony fishes. Irrespective of current phylogenetic uncertainty, the new data here resolve the likely general condition for ‘placoderms’ as a whole, and as such, ancestral morphology of known jawed vertebrates

CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4

CD80 and CD86 are expressed on antigen presenting cells and are required to engage their shared receptor, CD28, for the costimulation of CD4 T cells. It is unclear why two stimulatory ligands with overlapping roles have evolved. CD80 and CD86 also bind the regulatory molecule CTLA-4. We explored the role of CD80 and CD86 in the homeostasis and proliferation of CD4+FoxP3+ regulatory T cells (Treg), which constitutively express high levels of CTLA-4 yet are critically dependent upon CD28 signals. We observed that CD86 was the dominant ligand for Treg proliferation, survival, and maintenance of a regulatory phenotype, with higher expression of CTLA-4, ICOS, and OX40. We also explored whether CD80-CD28 interactions were specifically compromised by CTLA-4 and found that antibody blockade, clinical deficiency of CTLA-4 and CRISPR-Cas9 deletion of CTLA-4 all improved Treg survival following CD80 stimulation. Taken together, our data suggest that CD86 is the dominant costimulatory ligand for Treg homeostasis, despite its lower affinity for CD28, because CD80-CD28 interactions are selectively impaired by the high levels of CTLA-4. These data suggest a cell intrinsic role for CTLA-4 in regulating CD28 costimulation by direct competition for CD80, and indicate that that CD80 and CD86 have discrete roles in CD28 costimulation of CD4 T cells in the presence of high levels of CTLA-4